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Attempts to understand the mechanisms of mitochondrial diseases: The reverse genetics of mouse models for mitochondrial disease

Biochimica et biophysica acta. General subjects, 2021-03, Vol.1865 (3), p.129835, Article 129835

2021

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Accumulation of mitochondrial DNA with a point mutation in tRNALeu(UUR) gene induces brain dysfunction in mice

Pharmacological research, 2024-10, Vol.208, p.107374, Article 107374

2024

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Pearson syndrome: a multisystem mitochondrial disease with bone marrow failure

Orphanet journal of rare diseases, 2022-10, Vol.17 (1), p.1-379, Article 379

2022

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ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis

Science (American Association for the Advancement of Science), 2008-05, Vol.320 (5876), p.661-664

2008

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A high mutation load of m.14597A>G in MT-ND6 causes Leigh syndrome

Scientific reports, 2021-05, Vol.11 (1), p.11123-11123, Article 11123

2021

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Aberrant RNA processing contributes to the pathogenesis of mitochondrial diseases in trans-mitochondrial mouse model carrying mitochondrial tRNALeu(UUR) with a pathogenic A2748G mutation

Nucleic acids research, 2022-09, Vol.50 (16), p.9382-9396

2022

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Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects

Scientific reports, 2015-05, Vol.5 (1), p.10434-10434, Article 10434

2015

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Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells

Oncology reports, 2022-02, Vol.47 (2), p.1, Article 32

2022

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Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice

PloS one, 2017-11, Vol.12 (11), p.e0187894-e0187894

2017

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Acquired Expression of Mutant Mitofusin 2 Causes Progressive Neurodegeneration and Abnormal Behavior

The Journal of neuroscience, 2019-02, Vol.39 (9), p.1588-1604

2019

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Role of the Low-Density Lipoprotein-Cholesterol/High-Density Lipoprotein-Cholesterol Ratio in Predicting Serial Changes in the Lipid Component of Coronary Plaque

Circulation Journal, 2017/09/25, Vol.81(10), pp.1439-1446

2017

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Development of a Novel Algorithm to Detect Atrial Fibrillation Using an Automated Blood Pressure Monitor With an Irregular Heartbeat Detector

Circulation Journal, 2019/11/25, Vol.83(12), pp.2428-2433

2019

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Changes in Cell-Mediated Immunity (IFN-γ and Granzyme B) Following Influenza Vaccination

Viruses, 2021-06, Vol.13 (6), p.1137

2021

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Potential of the TRPM7 channel as a novel therapeutic target for pulmonary arterial hypertension

Journal of smooth muscle research, 2022, Vol.58, p.50-62, Article 0534

2022

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Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitive prostate cancer model

European journal of pharmacology, 2018-06, Vol.828, p.126-134

2018

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RLR-mediated antiviral innate immunity requires oxidative phosphorylation activity

Scientific reports, 2017-07, Vol.7 (1), p.5379-12, Article 5379

2017

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Information provision and retrieval by registered salespersons from consumers during over-the-counter drug sales - a questionnaire survey

BMC health services research, 2021-12, Vol.21 (1), p.1333-1333, Article 1333

2021

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Mitochondrial DNA mutations regulate metastasis of human breast cancer cells

PloS one, 2011-08, Vol.6 (8), p.e23401-e23401

2011

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Correlation between Antimicrobial Resistance and the Hospital-Wide Diverse Use of Broad-Spectrum Antibiotics by the Antimicrobial Stewardship Program in Japan

Pharmaceutics, 2023-02, Vol.15 (2), p.518

2023

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Concentration of mitochondrial DNA mutations by cytoplasmic transfer from platelets to cultured mouse cells

PloS one, 2019-03, Vol.14 (3), p.e0213283-e0213283

2019

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A novel mutation in TAZ causes mitochondrial respiratory chain disorder without cardiomyopathy

Journal of human genetics, 2017-05, Vol.62 (5), p.539-547

2017

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A novel function of mtDNA: its involvement in metastasis

Annals of the New York Academy of Sciences, 2010-07, Vol.1201 (1), p.40-43

2010

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Correction of thrombocytopenia caused by linezolid with scheduled sequential tedizolid use in patients with vertebral osteomyelitis by antibiotic resistant Gram-positive organisms

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2022-07, Vol.28 (7), p.1023-1028

2022

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Comparison of the Hemagglutination Inhibition Titers against Influenza Vaccine Strains in Japan from the 2017/2018 to 2021/2022 Seasons Using a Single Set of Serum Samples

Viruses, 2022-06, Vol.14 (7), p.1455

2022

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Chronic Administration of the Metastin/Kisspeptin Analog KISS1-305 or the Investigational Agent TAK-448 Suppresses Hypothalamic Pituitary Gonadal Function and Depletes Plasma Testosterone in Adult Male Rats

Endocrinology (Philadelphia), 2012-11, Vol.153 (11), p.5297-5308

2012

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Attempts to understand the mechanisms of mitochondrial diseases: The reverse genetics of mouse models for mitochondrial disease

Accumulation of mitochondrial DNA with a point mutation in tRNALeu(UUR) gene induces brain dysfunction in mice

Pearson syndrome: a multisystem mitochondrial disease with bone marrow failure

ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis

A high mutation load of m.14597A>G in MT-ND6 causes Leigh syndrome

Aberrant RNA processing contributes to the pathogenesis of mitochondrial diseases in trans-mitochondrial mouse model carrying mitochondrial tRNALeu(UUR) with a pathogenic A2748G mutation

Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects

Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells

Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice

Acquired Expression of Mutant Mitofusin 2 Causes Progressive Neurodegeneration and Abnormal Behavior

Role of the Low-Density Lipoprotein-Cholesterol/High-Density Lipoprotein-Cholesterol Ratio in Predicting Serial Changes in the Lipid Component of Coronary Plaque

Development of a Novel Algorithm to Detect Atrial Fibrillation Using an Automated Blood Pressure Monitor With an Irregular Heartbeat Detector

Changes in Cell-Mediated Immunity (IFN-γ and Granzyme B) Following Influenza Vaccination

Potential of the TRPM7 channel as a novel therapeutic target for pulmonary arterial hypertension

Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitive prostate cancer model

RLR-mediated antiviral innate immunity requires oxidative phosphorylation activity

Information provision and retrieval by registered salespersons from consumers during over-the-counter drug sales - a questionnaire survey

Mitochondrial DNA mutations regulate metastasis of human breast cancer cells

Correlation between Antimicrobial Resistance and the Hospital-Wide Diverse Use of Broad-Spectrum Antibiotics by the Antimicrobial Stewardship Program in Japan

Concentration of mitochondrial DNA mutations by cytoplasmic transfer from platelets to cultured mouse cells

A novel mutation in TAZ causes mitochondrial respiratory chain disorder without cardiomyopathy

A novel function of mtDNA: its involvement in metastasis

Correction of thrombocytopenia caused by linezolid with scheduled sequential tedizolid use in patients with vertebral osteomyelitis by antibiotic resistant Gram-positive organisms

Comparison of the Hemagglutination Inhibition Titers against Influenza Vaccine Strains in Japan from the 2017/2018 to 2021/2022 Seasons Using a Single Set of Serum Samples

Chronic Administration of the Metastin/Kisspeptin Analog KISS1-305 or the Investigational Agent TAK-448 Suppresses Hypothalamic Pituitary Gonadal Function and Depletes Plasma Testosterone in Adult Male Rats

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