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Fibroblast Biomarkers of Sporadic Parkinson’s Disease and LRRK2 Kinase Inhibition

Molecular neurobiology, 2016-10, Vol.53 (8), p.5161-5177

2016

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Gene therapy by proteasome activator, PA28γ, improves motor coordination and proteasome function in Huntington’s disease YAC128 mice

Neuroscience, 2016-06, Vol.324, p.20-28

2016

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Integrated molecular landscape of Parkinson's disease

NPJ Parkinson's Disease, 2017-04, Vol.3 (1), p.14-7, Article 14

2017

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In vivo modeling of neuronal function, axonal impairment and connectivity in neurodegenerative and neuropsychiatric disorders using induced pluripotent stem cells

Molecular and cellular neuroscience, 2016-06, Vol.73, p.3-12

2016

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Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging

The European journal of neuroscience, 2002-03, Vol.15 (6), p.991-998

2002

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IPS cell-derived retinal cell tranplantation

Journal of the neurological sciences, 2017-10, Vol.381, p.48-49

Isacson, O.

2017

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Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson’s disease

Neurobiology of disease, 2008-01, Vol.29 (1), p.103-116

2008

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Compensatory changes in the ubiquitin–proteasome system, brain-derived neurotrophic factor and mitochondrial complex II/III in YAC72 and R6/2 transgenic mice partially model Huntington's disease patients

Human molecular genetics, 2008-10, Vol.17 (20), p.3144-3153

2008

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Enhanced binding of metabotropic glutamate receptor type 5 (mGluR5) PET tracers in the brain of parkinsonian primates

NeuroImage (Orlando, Fla.), 2008-08, Vol.42 (1), p.248-251

2008

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Alzheimer's disease and Down's syndrome: roles of APP, trophic factors and ACh

Trends in neurosciences (Regular ed.), 2002-02, Vol.25 (2), p.79-84

2002

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Implanted reuptake-deficient or wild-type dopaminergic neurons improve ON l-dopa dyskinesias without OFF-dyskinesias in a rat model of Parkinson's disease

Brain (London, England : 1878), 2008-12, Vol.131 (12), p.3361-3379

2008

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Cognitive Changes and Modified Processing of Amyloid Precursor Protein in the Cortical and Hippocampal System after Cholinergic Synapse Loss and Muscarinic Receptor Activation

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (21), p.12108-12113

1999

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A high-efficiency synthetic promoter that drives transgene expression selectively in noradrenergic neurons

Human gene therapy, 2001-09, Vol.12 (14), p.1731-1740

2001

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1.2.2 USING STEM CELLS AND IPS CELLS TO DISCOVER NEW TREATMENTS FOR PARKINSON'S DISEASE

Parkinsonism & related disorders, 2012-01, Vol.18, p.S2-S2

2012

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Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

Cell, 2009-03, Vol.136 (5), p.964-977

2009

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Transplantation of embryonic porcine mesencephalic tissue in patients with PD

Neurology, 2000-03, Vol.54 (5), p.1042

2000

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On neuronal health

Trends in neurosciences (Regular ed.), 1993-08, Vol.16 (8), p.306-308

Isacson, O.

1993

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The lateral ganglionic eminence is the origin of cells committed to striatal phenotypes: neural transplantation and developmental evidence

Brain research, 1994-12, Vol.668 (1), p.211-219

1994

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Intrastriatal transforming growth factor alpha delivery to a model of Parkinson's disease induces proliferation and migration of endogenous adult neural progenitor cells without differentiation into dopaminergic neurons

The Journal of neuroscience, 2004-10, Vol.24 (41), p.8924-8931

2004

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Impact of genomics on drug discovery and clinical medicine

QJM : An International Journal of Medicine, 2000-07, Vol.93 (7), p.391-423

2000

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Gene therapy in the CNS

Gene therapy, 2000, Vol.7 (2), p.93-109

2000

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Specific axon guidance factors persist in the adult brain as demonstrated by pig neuroblasts transplanted to the rat

Neuroscience, 1996-12, Vol.75 (3), p.827-837

1996

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The production and use of cells as therapeutic agents in neurodegenerative diseases

Lancet neurology, 2003-07, Vol.2 (7), p.417-424

Isacson, Ole

2003

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Neural xenotransplantation: Reconstruction of neuronal circuitry across species barriers

Neuroscience, 1994-10, Vol.62 (4), p.989-1001

1994

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Immunophilin Ligands and GDNF Enhance Neurite Branching or Elongation from Developing Dopamine Neurons in Culture

Experimental neurology, 2000-07, Vol.164 (1), p.60-70

2000

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Fibroblast Biomarkers of Sporadic Parkinson’s Disease and LRRK2 Kinase Inhibition

Gene therapy by proteasome activator, PA28γ, improves motor coordination and proteasome function in Huntington’s disease YAC128 mice

Integrated molecular landscape of Parkinson's disease

In vivo modeling of neuronal function, axonal impairment and connectivity in neurodegenerative and neuropsychiatric disorders using induced pluripotent stem cells

Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging

IPS cell-derived retinal cell tranplantation

Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson’s disease

Compensatory changes in the ubiquitin–proteasome system, brain-derived neurotrophic factor and mitochondrial complex II/III in YAC72 and R6/2 transgenic mice partially model Huntington's disease patients

Enhanced binding of metabotropic glutamate receptor type 5 (mGluR5) PET tracers in the brain of parkinsonian primates

Alzheimer's disease and Down's syndrome: roles of APP, trophic factors and ACh

Implanted reuptake-deficient or wild-type dopaminergic neurons improve ON l-dopa dyskinesias without OFF-dyskinesias in a rat model of Parkinson's disease

Cognitive Changes and Modified Processing of Amyloid Precursor Protein in the Cortical and Hippocampal System after Cholinergic Synapse Loss and Muscarinic Receptor Activation

A high-efficiency synthetic promoter that drives transgene expression selectively in noradrenergic neurons

1.2.2 USING STEM CELLS AND IPS CELLS TO DISCOVER NEW TREATMENTS FOR PARKINSON'S DISEASE

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

Transplantation of embryonic porcine mesencephalic tissue in patients with PD

On neuronal health

The lateral ganglionic eminence is the origin of cells committed to striatal phenotypes: neural transplantation and developmental evidence

Intrastriatal transforming growth factor alpha delivery to a model of Parkinson's disease induces proliferation and migration of endogenous adult neural progenitor cells without differentiation into dopaminergic neurons

Impact of genomics on drug discovery and clinical medicine

Gene therapy in the CNS

Specific axon guidance factors persist in the adult brain as demonstrated by pig neuroblasts transplanted to the rat

The production and use of cells as therapeutic agents in neurodegenerative diseases

Neural xenotransplantation: Reconstruction of neuronal circuitry across species barriers

Immunophilin Ligands and GDNF Enhance Neurite Branching or Elongation from Developing Dopamine Neurons in Culture

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