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A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy

Nature communications, 2021-01, Vol.12 (1), p.430-430, Article 430

2021

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Non–clinical efficacy, safety and stable clinical cell processing of induced pluripotent stem cell‐derived anti–glypican‐3 chimeric antigen receptor‐expressing natural killer/innate lymphoid cells

Cancer science, 2020-05, Vol.111 (5), p.1478-1490

2020

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Toward the development of true “off‐the‐shelf” synthetic T‐cell immunotherapy

Cancer science, 2019-01, Vol.110 (1), p.16-22

2019

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Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells

Nature biomedical engineering, 2021-05, Vol.5 (5), p.429-440

2021

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Lineage tracing of T cell differentiation from T-iPSC by 2D feeder-free culture and 3D organoid culture

Frontiers in immunology, 2023, Vol.14, p.1303713-1303713

2023

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Effective and stable gene transduction in rhesus macaque iPSCs capable of T-lineage differentiation utilizing the piggyBac system

Regenerative therapy, 2024-12, Vol.27, p.104-111

2024

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Cellular Adjuvant Properties, Direct Cytotoxicity of Re-differentiated Vα24 Invariant NKT-like Cells from Human Induced Pluripotent Stem Cells

Stem cell reports, 2016-02, Vol.6 (2), p.213-227

2016

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The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells

Communications biology, 2021-06, Vol.4 (1), p.694-694

2021

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Generation of macrophages with altered viral sensitivity from genome-edited rhesus macaque iPSCs to model human disease

Molecular therapy. Methods & clinical development, 2021-06, Vol.21, p.262-273

2021

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Generation of HIV-Resistant Macrophages from IPSCs by Using Transcriptional Gene Silencing and Promoter-Targeted RNA

Molecular therapy. Nucleic acids, 2018-09, Vol.12, p.793-804

2018

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The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-derived iPS cells

Communications biology, 2021-06, Vol.4 (1), Article 694

2021

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Reprogramming away from the exhausted T cell state

Seminars in immunology, 2016-02, Vol.28 (1), p.35-44

2016

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Enhancing T Cell Receptor Stability in Rejuvenated iPSC-Derived T Cells Improves Their Use in Cancer Immunotherapy

Cell stem cell, 2018-12, Vol.23 (6), p.850-858.e4

2018

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iPSC-Derived HLA-A2 CAR Tregs Showed Suppression of GvHD in a Xenograft Model

Blood, 2022-11, Vol.140 (Supplement 1), p.2365-2366

2022

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Human iPSC-derived CD4+ Treg-like cells engineered with chimeric antigen receptors control GvHD in a xenograft model

Cell stem cell, 2024-06, Vol.31 (6), p.795-802.e6

2024

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Generation of Rejuvenated Antigen-Specific T Cells by Reprogramming to Pluripotency and Redifferentiation

Cell stem cell, 2013-01, Vol.12 (1), p.114-126

2013

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Guided Polarization of iPSC-Derived CD4SP Helper T Cells By CRISPR/Cas9-Based Genome-Editing

Blood, 2019-11, Vol.134 (Supplement_1), p.1937-1937

2019

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T-cell–restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung

Blood, 2015-01, Vol.125 (2), p.370-382

2015

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Abstract 1432: Enhanced effector responses of regenerated CAR-T cells derived from genome edited iPSCs

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.1432-1432

2019

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Abstract 2550: Generation of CAR-iPS-T cells expressing CD8β

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2550-2550

2018

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Over Molding Process Development for a Stacked Wafer-level Chip Scale Package with Through Silicon Vias (TSVs)

TRANSACTIONS OF THE JAPAN INSTITUTE OF ELECTRONICS PACKAGING, 2012, Vol.5 (1), p.122-131

2012

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Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells

Nature biomedical engineering, 2023-01, Vol.7 (1), p.24

2023

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T cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of lung macrophages in the lung

Experimental hematology, 2015-09, Vol.43 (9), p.S69-S69

2015

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Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response

Stem cell reports, 2018-06, Vol.10 (6), p.1935-1946

2018

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Abstract 5185: First in human trial of off-the shelf iPS derived anti-GPC3 NK cells for recurrent ovarian clear cell carcinoma with peritoneal dissemination

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.5185-5185

2022

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A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy

Non–clinical efficacy, safety and stable clinical cell processing of induced pluripotent stem cell‐derived anti–glypican‐3 chimeric antigen receptor‐expressing natural killer/innate lymphoid cells

Toward the development of true “off‐the‐shelf” synthetic T‐cell immunotherapy

Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells

Lineage tracing of T cell differentiation from T-iPSC by 2D feeder-free culture and 3D organoid culture

Effective and stable gene transduction in rhesus macaque iPSCs capable of T-lineage differentiation utilizing the piggyBac system

Cellular Adjuvant Properties, Direct Cytotoxicity of Re-differentiated Vα24 Invariant NKT-like Cells from Human Induced Pluripotent Stem Cells

The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells

Generation of macrophages with altered viral sensitivity from genome-edited rhesus macaque iPSCs to model human disease

Generation of HIV-Resistant Macrophages from IPSCs by Using Transcriptional Gene Silencing and Promoter-Targeted RNA

The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-derived iPS cells

Reprogramming away from the exhausted T cell state

Enhancing T Cell Receptor Stability in Rejuvenated iPSC-Derived T Cells Improves Their Use in Cancer Immunotherapy

iPSC-Derived HLA-A2 CAR Tregs Showed Suppression of GvHD in a Xenograft Model

Human iPSC-derived CD4+ Treg-like cells engineered with chimeric antigen receptors control GvHD in a xenograft model

Generation of Rejuvenated Antigen-Specific T Cells by Reprogramming to Pluripotency and Redifferentiation

Guided Polarization of iPSC-Derived CD4SP Helper T Cells By CRISPR/Cas9-Based Genome-Editing

T-cell–restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung

Abstract 1432: Enhanced effector responses of regenerated CAR-T cells derived from genome edited iPSCs

Abstract 2550: Generation of CAR-iPS-T cells expressing CD8β

Over Molding Process Development for a Stacked Wafer-level Chip Scale Package with Through Silicon Vias (TSVs)

Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells

T cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of lung macrophages in the lung

Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response

Abstract 5185: First in human trial of off-the shelf iPS derived anti-GPC3 NK cells for recurrent ovarian clear cell carcinoma with peritoneal dissemination

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