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RTX proteins: a highly diverse family secreted by a common mechanism

FEMS microbiology reviews, 2010-11, Vol.34 (6), p.1076-1112

2010

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Physical modalities inducing immunogenic tumor cell death for cancer immunotherapy

Oncoimmunology, 2014-12, Vol.3 (12), p.e968434-e968434

2014

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High hydrostatic pressure in cancer immunotherapy and biomedicine

Biotechnology advances, 2018-05, Vol.36 (3), p.577-582

2018

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Invasion of Dendritic Cells, Macrophages and Neutrophils by the Bordetella Adenylate Cyclase Toxin: A Subversive Move to Fool Host Immunity

Toxins, 2017-09, Vol.9 (10), p.293

2017

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Severe, but not mild heat-shock treatment induces immunogenic cell death in cancer cells

Oncoimmunology, 2017-05, Vol.6 (5), p.e1311433-e1311433

2017

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Myeloid - derived suppressor cells in Type 1 diabetes are an expanded population exhibiting diverse T-cell suppressor mechanisms

PloS one, 2020-11, Vol.15 (11), p.e0242092-e0242092

2020

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Generation of dendritic cell-based vaccine using high hydrostatic pressure for non-small cell lung cancer immunotherapy

PloS one, 2017-02, Vol.12 (2), p.e0171539-e0171539

2017

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SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity

Frontiers in immunology, 2022-10, Vol.13, p.989895-989895

2022

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Radiotherapy in Combination With Cytokine Treatment

Frontiers in oncology, 2019-05, Vol.9, p.367-367

2019

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Bacteria and their toxins tamed for immunotherapy

Current pharmaceutical biotechnology, 2012-06, Vol.13 (8), p.1446-1473

2012

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713 Nanrilkefusp alfa, a high-affinity IL-15Rβγ agonist, promotes an innate and adaptive anti-tumour inflammatory environment as single agent or combined with anti-PD-1 in patients with advanced cancers

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A808-A808

2023

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815 Combination with IL-15Rβγ superagonist, Nanrilkefusp alfa, enhances CAR T and BOXR T cell anti-tumor activity

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A914-A914

2023

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Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores

PLoS pathogens, 2012-04, Vol.8 (4), p.e1002580-e1002580

2012

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Bordetella adenylate cyclase toxin differentially modulates toll-like receptor-stimulated activation, migration and T cell stimulatory capacity of dendritic cells

PloS one, 2014-08, Vol.9 (8), p.e104064-e104064

2014

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1087 SOT201 is a novel cis-acting immunocytokine targeting IL-15Rβγ to reinvigorate PD-1+tumor infiltrating lymphocytes and potentiate anti-tumor efficacy

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1196-A1196

2023

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563 Pharmacodynamics and pharmacokinetics of SO-C101 in cynomolgus monkeys

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A339-A339

2020

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High hydrostatic pressure affects antigenic pool in tumor cells: Implication for dendritic cell-based cancer immunotherapy

Immunology letters, 2017-07, Vol.187, p.27-34

2017

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Abstract 6686: SO-C101 displays strong anti-tumor effect in TC-1 and TRAMP-C2 tumor mice and in combination with PD-1 blockade prevents tumor development in a NK and CD8+ T cells dependent manner

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6686-6686

2020

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Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis

Infection and immunity, 2017-06, Vol.85 (6)

2017

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Interim safety and efficacy results from AURELIO-03: A phase 1 dose escalation study of the IL-2/IL-15 receptor βγ superagonist SOT101 as a single agent and in combination with pembrolizumab in patients with advanced solid tumors

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.2502-2502

2022

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Detection of tumor antigens and tumor-antigen specific T cells in NSCLC patients: Correlation of the quality of T cell responses with NSCLC subtype

Immunology letters, 2020-03, Vol.219, p.46-53

2020

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Abstract A47: Immunogenic cancer cell death induced by high hydrostatic pressure and hyperthermia: Calreticulin exposure pathway

Cancer research (Chicago, Ill.), 2017-03, Vol.77 (6_Supplement), p.A47-A47

2017

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Abstract B82: Distinct immune status in patients with adenocarcinoma and squamous cell carcinoma: Implication for immunotherapy of non-small cell lung cancer

Cancer immunology research, 2020-04, Vol.8 (4_Supplement), p.B82-B82

2020

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Abstract 3775: Use of RLI-15 a clinical grade fusion protein with IL-15 superagonistic activity for the activation of anti-tumor immune response

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.3775-3775

2018

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Pore‐formation by adenylate cyclase toxoid activates dendritic cells to prime CD8+ and CD4+ T cells

Immunology and cell biology, 2016-04, Vol.94 (4), p.322-333

2016

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RTX proteins: a highly diverse family secreted by a common mechanism

Physical modalities inducing immunogenic tumor cell death for cancer immunotherapy

High hydrostatic pressure in cancer immunotherapy and biomedicine

Invasion of Dendritic Cells, Macrophages and Neutrophils by the Bordetella Adenylate Cyclase Toxin: A Subversive Move to Fool Host Immunity

Severe, but not mild heat-shock treatment induces immunogenic cell death in cancer cells

Myeloid - derived suppressor cells in Type 1 diabetes are an expanded population exhibiting diverse T-cell suppressor mechanisms

Generation of dendritic cell-based vaccine using high hydrostatic pressure for non-small cell lung cancer immunotherapy

SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity

Radiotherapy in Combination With Cytokine Treatment

Bacteria and their toxins tamed for immunotherapy

713 Nanrilkefusp alfa, a high-affinity IL-15Rβγ agonist, promotes an innate and adaptive anti-tumour inflammatory environment as single agent or combined with anti-PD-1 in patients with advanced cancers

815 Combination with IL-15Rβγ superagonist, Nanrilkefusp alfa, enhances CAR T and BOXR T cell anti-tumor activity

Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores

Bordetella adenylate cyclase toxin differentially modulates toll-like receptor-stimulated activation, migration and T cell stimulatory capacity of dendritic cells

1087 SOT201 is a novel cis-acting immunocytokine targeting IL-15Rβγ to reinvigorate PD-1+tumor infiltrating lymphocytes and potentiate anti-tumor efficacy

563 Pharmacodynamics and pharmacokinetics of SO-C101 in cynomolgus monkeys

High hydrostatic pressure affects antigenic pool in tumor cells: Implication for dendritic cell-based cancer immunotherapy

Abstract 6686: SO-C101 displays strong anti-tumor effect in TC-1 and TRAMP-C2 tumor mice and in combination with PD-1 blockade prevents tumor development in a NK and CD8+ T cells dependent manner

Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis

Interim safety and efficacy results from AURELIO-03: A phase 1 dose escalation study of the IL-2/IL-15 receptor βγ superagonist SOT101 as a single agent and in combination with pembrolizumab in patients with advanced solid tumors

Detection of tumor antigens and tumor-antigen specific T cells in NSCLC patients: Correlation of the quality of T cell responses with NSCLC subtype

Abstract A47: Immunogenic cancer cell death induced by high hydrostatic pressure and hyperthermia: Calreticulin exposure pathway

Abstract B82: Distinct immune status in patients with adenocarcinoma and squamous cell carcinoma: Implication for immunotherapy of non-small cell lung cancer

Abstract 3775: Use of RLI-15 a clinical grade fusion protein with IL-15 superagonistic activity for the activation of anti-tumor immune response

Pore‐formation by adenylate cyclase toxoid activates dendritic cells to prime CD8+ and CD4+ T cells

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