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inflammatory cytokine, interleukin-1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute viral encephalomyelitis

Journal of neurochemistry, 2008-05, Vol.105 (4), p.1276-1286

2008

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Discovery of potent broad spectrum antivirals derived from marine actinobacteria

PloS one, 2013-12, Vol.8 (12), p.e82318

2013

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Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis

Nature communications, 2020-08, Vol.11 (1), p.3871-3871, Article 3871

2020

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Aseptic Meningitis and Viral Myelitis

Neurologic clinics, 2008-08, Vol.26 (3), p.635-655

Irani, David N., MD

2008

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Dysregulation of the IL-23/IL-17 axis and myeloid factors in secondary progressive MS

Neurology, 2014-10, Vol.83 (17), p.1500-1507

2014

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Type-I interferons suppress microglial production of the lymphoid chemokine, CXCL13

Glia, 2014-09, Vol.62 (9), p.1452-1462

2014

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Progressive multifocal leukoencephalopathy selectively affecting Broca's and Wernicke's areas in an immunocompetent patient: A case report

Radiology case reports, 2023-03, Vol.18 (3), p.1334-1336

2023

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Astrocyte matricellular proteins that control excitatory synaptogenesis are regulated by inflammatory cytokines and correlate with paralysis severity during experimental autoimmune encephalomyelitis

Frontiers in neuroscience, 2015-10, Vol.9, p.344-344

2015

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Optimization of Novel Indole-2-carboxamide Inhibitors of Neurotropic Alphavirus Replication

Journal of medicinal chemistry, 2013-11, Vol.56 (22), p.9222-9241

2013

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An emerging role for eotaxins in neurodegenerative disease

Clinical immunology (Orlando, Fla.), 2018-04, Vol.189, p.29-33

2018

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Is the concept of central nervous system immune privilege irrelevant in the setting of acute infection?

Frontiers in oncology, 2015-04, Vol.5, p.99-99

2015

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Neuroprotective Interventions Targeting Detrimental Host Immune Responses Protect Mice From Fatal Alphavirus Encephalitis

Journal of neuropathology and experimental neurology, 2007-06, Vol.66 (6), p.533-544

2007

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Viral-Induced Spinal Motor Neuron Death Is Non-Cell-Autonomous and Involves Glutamate Excitotoxicity

The Journal of neuroscience, 2004-08, Vol.24 (34), p.7566-7575

2004

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Immune responses to non-tumor antigens in the central nervous system

Frontiers in oncology, 2014-01, Vol.4, p.328-328

2014

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Complexity of the microglial activation pathways that drive innate host responses during lethal alphavirus encephalitis in mice

ASN neuro, 2012-05, Vol.4 (4), p.207-221

2012

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Cerebrospinal fluid protein carbonylation identifies oxidative damage in autoimmune demyelination

Annals of clinical and translational neurology, 2017-02, Vol.4 (2), p.145-150

Irani, David N.

2017

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Type-1 angiotensin receptor signaling in central nervous system myeloid cells is pathogenic during fatal alphavirus encephalitis in mice

Journal of neuroinflammation, 2016-08, Vol.13 (1), p.196-196, Article 196

2016

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Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems

The Journal of biological chemistry, 2016-02, Vol.291 (6), p.3030-3042

2016

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Inflammatory bowel disease patient concerns and experiences on transition to home-based infusions during the COVID-19 pandemic

Research in social and administrative pharmacy, 2022-12, Vol.18 (12), p.4138-4143

2022

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Regulated Production of CXCL13 within the Central Nervous System

Journal of clinical & cellular immunology, 2016-10, Vol.7 (5)

Irani, David N

2016

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Human Embryonic Germ Cell Derivatives Facilitate Motor Recovery of Rats with Diffuse Motor Neuron Injury

The Journal of neuroscience, 2003-06, Vol.23 (12), p.5131-5140

2003

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Targeting CXCL13 During Neuroinflammation

Advances in neuroimmune biology, 2015-01, Vol.6 (1), p.1-8

2015

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The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system

Brain, behavior, and immunity, 2011-07, Vol.25 (5), p.922-931

2011

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The conundrum of interferon-β non-responsiveness in relapsing–remitting multiple sclerosis

Cytokine (Philadelphia, Pa.), 2015-08, Vol.74 (2), p.228-236

2015

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BCL-2 and BAX Protect Adult Mice from Lethal Sindbis Virus Infection but Do Not Protect Spinal Cord Motor Neurons or Prevent Paralysis

Journal of Virology, 2002-10, Vol.76 (20), p.10393-10400

2002

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inflammatory cytokine, interleukin-1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute viral encephalomyelitis

Discovery of potent broad spectrum antivirals derived from marine actinobacteria

Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis

Aseptic Meningitis and Viral Myelitis

Dysregulation of the IL-23/IL-17 axis and myeloid factors in secondary progressive MS

Type-I interferons suppress microglial production of the lymphoid chemokine, CXCL13

Progressive multifocal leukoencephalopathy selectively affecting Broca's and Wernicke's areas in an immunocompetent patient: A case report

Astrocyte matricellular proteins that control excitatory synaptogenesis are regulated by inflammatory cytokines and correlate with paralysis severity during experimental autoimmune encephalomyelitis

Optimization of Novel Indole-2-carboxamide Inhibitors of Neurotropic Alphavirus Replication

An emerging role for eotaxins in neurodegenerative disease

Is the concept of central nervous system immune privilege irrelevant in the setting of acute infection?

Neuroprotective Interventions Targeting Detrimental Host Immune Responses Protect Mice From Fatal Alphavirus Encephalitis

Viral-Induced Spinal Motor Neuron Death Is Non-Cell-Autonomous and Involves Glutamate Excitotoxicity

Immune responses to non-tumor antigens in the central nervous system

Complexity of the microglial activation pathways that drive innate host responses during lethal alphavirus encephalitis in mice

Cerebrospinal fluid protein carbonylation identifies oxidative damage in autoimmune demyelination

Type-1 angiotensin receptor signaling in central nervous system myeloid cells is pathogenic during fatal alphavirus encephalitis in mice

Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems

Inflammatory bowel disease patient concerns and experiences on transition to home-based infusions during the COVID-19 pandemic

Regulated Production of CXCL13 within the Central Nervous System

Human Embryonic Germ Cell Derivatives Facilitate Motor Recovery of Rats with Diffuse Motor Neuron Injury

Targeting CXCL13 During Neuroinflammation

The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system

The conundrum of interferon-β non-responsiveness in relapsing–remitting multiple sclerosis

BCL-2 and BAX Protect Adult Mice from Lethal Sindbis Virus Infection but Do Not Protect Spinal Cord Motor Neurons or Prevent Paralysis

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