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Asymmetric Total Syntheses of Rhynchophylline and Isorhynchophylline

Journal of organic chemistry, 2019-09, Vol.84 (17), p.11359-11365

2019

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Large‐scale plasma proteomic profiling identifies a high‐performance biomarker panel for Alzheimer's disease screening and staging

Alzheimer's & dementia, 2022-01, Vol.18 (1), p.88-102

2022

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Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer’s disease

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (27), p.9959-9964

2014

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Diarylheptanoids from Rhizomes of Alpinia officinarum Inhibit Aggregation of α‑Synuclein

Journal of agricultural and food chemistry, 2017-08, Vol.65 (31), p.6608-6614

2017

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Using blood transcriptome analysis for Alzheimer's disease diagnosis and patient stratification

Alzheimer's & dementia, 2024-04, Vol.20 (4), p.2469-2484

2024

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Rhynchophylline Administration Ameliorates Amyloid‑β Pathology and Inflammation in an Alzheimer’s Disease Transgenic Mouse Model

ACS chemical neuroscience, 2021-11, Vol.12 (22), p.4249-4256

2021

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Identification of new EphA4 inhibitors by virtual screening of FDA-approved drugs

Scientific reports, 2018-05, Vol.8 (1), p.7377-7, Article 7377

2018

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Association of SPI1 Haplotypes with Altered SPI1 Gene Expression and Alzheimer's Disease Risk

Journal of Alzheimer's disease, 2022-01, Vol.86 (4), p.1861

2022

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A Pentacyclic Triterpene from Ligustrum lucidum Targets γ‑Secretase

ACS chemical neuroscience, 2020-09, Vol.11 (18), p.2827-2835

2020

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Anemoside A3 ameliorates experimental autoimmune encephalomyelitis by modulating T helper 17 cell response

PloS one, 2017-07, Vol.12 (7), p.e0182069-e0182069

2017

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Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors

Bioorganic & medicinal chemistry, 2013-02, Vol.21 (3), p.676-683

2013

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Design and Synthesis of Dimeric Securinine Analogues with Neuritogenic Activities

ACS chemical neuroscience, 2016-10, Vol.7 (10), p.1442-1451

2016

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Aberrant Motor Axon Projection, Acetylcholine Receptor Clustering, and Neurotransmission in Cyclin-Dependent Kinase 5 Null Mice

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (42), p.15224-15229

2005

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Ephexin1 Is Required for Structural Maturation and Neurotransmission at the Neuromuscular Junction

Neuron (Cambridge, Mass.), 2010-01, Vol.65 (2), p.204-216

2010

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Olean-12-eno[2,3-c] [1,2,5]oxadiazol-28-oic acid (OEOA) induces G1 cell cycle arrest and differentiation in human leukemia cell lines

PloS one, 2013-05, Vol.8 (5), p.e63580-e63580

2013

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Anemoside A3 Enhances Cognition through the Regulation of Synaptic Function and Neuroprotection

Neuropsychopharmacology (New York, N.Y.), 2015-07, Vol.40 (8), p.1877-1887

2015

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Dammarane saponins from Gynostemma pentaphyllum

Phytochemistry (Oxford), 2010-07, Vol.71 (10), p.1149-1157

2010

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Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population

Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2020, Vol.12 (1), p.e12074-n/a

2020

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Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction

Nature neuroscience, 2001-04, Vol.4 (4), p.374-381

2001

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Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types

Planta medica, 2012-01, Vol.78 (2), p.115

2012

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Highly trans-Selective Arylation of Achmatowicz Rearrangement Products by Reductive γ-Deoxygenation and Heck-Matsuda Reaction: Asymmetric Total Synthesis of (−)-Musellarins A-C and Their Analogues

Chemistry : a European journal, 2015-07, Vol.21 (31), p.11152-11157

2015

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A tacrine-tetrahydroquinoline heterodimer potently inhibits acetylcholinesterase activity and enhances neurotransmission in mice

European journal of medicinal chemistry, 2021-12, Vol.226, p.113827-113827, Article 113827

2021

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New secoiridoid glucosides from Ligustrum lucidum induce ERK and CREB phosphorylation in cultured cortical neurons

Planta medica, 2010-07, Vol.76 (10), p.998

2010

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Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease

The Journal of neuroscience, 2010-05, Vol.30 (20), p.6873-6881

2010

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Coronin 6 regulates acetylcholine receptor clustering through modulating receptor anchorage to actin cytoskeleton

The Journal of neuroscience, 2014-02, Vol.34 (7), p.2413-2421

2014

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Asymmetric Total Syntheses of Rhynchophylline and Isorhynchophylline

Large‐scale plasma proteomic profiling identifies a high‐performance biomarker panel for Alzheimer's disease screening and staging

Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer’s disease

Diarylheptanoids from Rhizomes of Alpinia officinarum Inhibit Aggregation of α‑Synuclein

Using blood transcriptome analysis for Alzheimer's disease diagnosis and patient stratification

Rhynchophylline Administration Ameliorates Amyloid‑β Pathology and Inflammation in an Alzheimer’s Disease Transgenic Mouse Model

Identification of new EphA4 inhibitors by virtual screening of FDA-approved drugs

Association of SPI1 Haplotypes with Altered SPI1 Gene Expression and Alzheimer's Disease Risk

A Pentacyclic Triterpene from Ligustrum lucidum Targets γ‑Secretase

Anemoside A3 ameliorates experimental autoimmune encephalomyelitis by modulating T helper 17 cell response

Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors

Design and Synthesis of Dimeric Securinine Analogues with Neuritogenic Activities

Aberrant Motor Axon Projection, Acetylcholine Receptor Clustering, and Neurotransmission in Cyclin-Dependent Kinase 5 Null Mice

Ephexin1 Is Required for Structural Maturation and Neurotransmission at the Neuromuscular Junction

Olean-12-eno[2,3-c] [1,2,5]oxadiazol-28-oic acid (OEOA) induces G1 cell cycle arrest and differentiation in human leukemia cell lines

Anemoside A3 Enhances Cognition through the Regulation of Synaptic Function and Neuroprotection

Dammarane saponins from Gynostemma pentaphyllum

Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population

Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction

Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types

Highly trans-Selective Arylation of Achmatowicz Rearrangement Products by Reductive γ-Deoxygenation and Heck-Matsuda Reaction: Asymmetric Total Synthesis of (−)-Musellarins A-C and Their Analogues

A tacrine-tetrahydroquinoline heterodimer potently inhibits acetylcholinesterase activity and enhances neurotransmission in mice

New secoiridoid glucosides from Ligustrum lucidum induce ERK and CREB phosphorylation in cultured cortical neurons

Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease

Coronin 6 regulates acetylcholine receptor clustering through modulating receptor anchorage to actin cytoskeleton

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