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Antiprotozoal Activity Profiling of Approved Drugs: A Starting Point toward Drug Repositioning

PloS one, 2015-08, Vol.10 (8), p.e0135556-e0135556

2015

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Drug discovery and development for neglected diseases: the DNDi model

Drug design, development and therapy, 2011-03, Vol.5 (default), p.175-181

2011

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Repurposing of the Open Access Malaria Box for Kinetoplastid Diseases Identifies Novel Active Scaffolds against Trypanosomatids

Journal of biomolecular screening, 2015-06, Vol.20 (5), p.634-645

2015

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Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign

PLoS neglected tropical diseases, 2012-11, Vol.6 (11), p.e1896

2012

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Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity

PLoS neglected tropical diseases, 2015-09, Vol.9 (9), p.e0004094-e0004094

2015

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Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis

International journal for parasitology -- drugs and drug resistance, 2019-12, Vol.11, p.129-138

2019

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Madurastatins with Imidazolidinone Rings: Natural Products or Side-Reaction Products from Extraction Solvents?

International journal of molecular sciences, 2023-12, Vol.25 (1), p.301

2023

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Phenotypic screening approaches for Chagas disease drug discovery

Expert opinion on drug discovery, 2018-02, Vol.13 (2), p.141-153

2018

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Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma

PLoS neglected tropical diseases, 2018-04, Vol.12 (4), p.e0006437-e0006437

2018

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Simple field assays to check quality of current artemisinin-based antimalarial combination formulations

PloS one, 2009-09, Vol.4 (9), p.e7270-e7270

2009

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Screening strategies to identify new chemical diversity for drug development to treat kinetoplastid infections

Parasitology, 2014-01, Vol.141 (1), p.140-146

2014

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Assessing anti-T. cruzi candidates in vitro for sterile cidality

International journal for parasitology -- drugs and drug resistance, 2016-12, Vol.6 (3), p.165-170

2016

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A Sample-Centric and Knowledge-Driven Computational Framework for Natural Products Drug Discovery

ACS central science, 2024-03, Vol.10 (3), p.494-510

2024

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Novel 3-Nitro-1 H -1,2,4-triazole-Based Amides and Sulfonamides as Potential Antitrypanosomal Agents

Journal of medicinal chemistry, 2012-06, Vol.55 (11), p.5554-5565

2012

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Limonoid Orthoacetates and Antiprotozoal Compounds from the Roots of Pseudocedrela kotschyi

Journal of natural products (Washington, D.C.), 2007-01, Vol.70 (1), p.9-13

2007

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Novel 3-Nitro-1H-1,2,4-triazole-Based Amides and Sulfonamides as Potential Antitrypanosomal Agents

Journal of medicinal chemistry, 2012-06, Vol.55 (11), p.5554-5565

2012

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Novel 3‑Nitrotriazole-Based Amides and Carbinols as Bifunctional Antichagasic Agents

Journal of medicinal chemistry, 2015-02, Vol.58 (3), p.1307-1319

2015

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Discovery of potent nitrotriazole-based antitrypanosomal agents: In vitro and in vivo evaluation

Bioorganic & medicinal chemistry, 2015-10, Vol.23 (19), p.6467-6476

2015

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Novel 3-nitro-1H-1,2,4-triazole-based piperazines and 2-amino-1,3-benzothiazoles as antichagasic agents

Bioorganic & medicinal chemistry, 2013-11, Vol.21 (21), p.6600-6607

2013

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Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals

Bioorganic & medicinal chemistry, 2016-04, Vol.24 (7), p.1573-1581

2016

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Drugs for Neglected Diseases initiative model of drug development for neglected diseases: current status and future challenges

Future medicinal chemistry, 2011-09, Vol.3 (11), p.1361-1371

2011

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Catechol Pyrazolinones as Trypanocidals: Fragment-Based Design, Synthesis, and Pharmacological Evaluation of Nanomolar Inhibitors of Trypanosomal Phosphodiesterase B1

Journal of medicinal chemistry, 2012-10, Vol.55 (20), p.8745-8756

2012

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Flavonoid profiling among wild type and related GM wheat varieties

Plant molecular biology, 2007-11, Vol.65 (5), p.645-654

2007

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Antileishmanial activities associated with plants used in the Malian traditional medicine

Journal of ethnopharmacology, 2007-03, Vol.110 (1), p.99-104

2007

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Evaluation of Parameters Impacting Drug Susceptibility in Intracellular Trypanosoma cruzi Assay Protocols

SLAS discovery, 2017-02, Vol.22 (2), p.125-134

2017

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Antiprotozoal Activity Profiling of Approved Drugs: A Starting Point toward Drug Repositioning

Drug discovery and development for neglected diseases: the DNDi model

Repurposing of the Open Access Malaria Box for Kinetoplastid Diseases Identifies Novel Active Scaffolds against Trypanosomatids

Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign

Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity

Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis

Madurastatins with Imidazolidinone Rings: Natural Products or Side-Reaction Products from Extraction Solvents?

Phenotypic screening approaches for Chagas disease drug discovery

Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma

Simple field assays to check quality of current artemisinin-based antimalarial combination formulations

Screening strategies to identify new chemical diversity for drug development to treat kinetoplastid infections

Assessing anti-T. cruzi candidates in vitro for sterile cidality

A Sample-Centric and Knowledge-Driven Computational Framework for Natural Products Drug Discovery

Novel 3-Nitro-1 H -1,2,4-triazole-Based Amides and Sulfonamides as Potential Antitrypanosomal Agents

Limonoid Orthoacetates and Antiprotozoal Compounds from the Roots of Pseudocedrela kotschyi

Novel 3-Nitro-1H-1,2,4-triazole-Based Amides and Sulfonamides as Potential Antitrypanosomal Agents

Novel 3‑Nitrotriazole-Based Amides and Carbinols as Bifunctional Antichagasic Agents

Discovery of potent nitrotriazole-based antitrypanosomal agents: In vitro and in vivo evaluation

Novel 3-nitro-1H-1,2,4-triazole-based piperazines and 2-amino-1,3-benzothiazoles as antichagasic agents

Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals

Drugs for Neglected Diseases initiative model of drug development for neglected diseases: current status and future challenges

Catechol Pyrazolinones as Trypanocidals: Fragment-Based Design, Synthesis, and Pharmacological Evaluation of Nanomolar Inhibitors of Trypanosomal Phosphodiesterase B1

Flavonoid profiling among wild type and related GM wheat varieties

Antileishmanial activities associated with plants used in the Malian traditional medicine

Evaluation of Parameters Impacting Drug Susceptibility in Intracellular Trypanosoma cruzi Assay Protocols

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