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Tissue distribution and biotransformation of zopolrestat, an aldose reductase inhibitor, in rats

Drug metabolism and disposition, 1998-11, Vol.26 (11), p.1149

1998

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Pharmacological properties of a novel ACAT inhibitor (CP-113,818) in cholesterol-fed rats, hamsters, rabbits, and monkeys

Journal of lipid research, 1994-10, Vol.35 (10), p.1829-1838

1994

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Theoretical considerations on two equations for estimating the extent of absorption after oral administration of drugs

Pharmaceutical research, 1996-04, Vol.13 (4), p.566-569

1996

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Bioavailability, multiple-dose pharmacokinetics, and biotransformation of the aldose reductase inhibitor zopolrestat in dogs

Drug metabolism and disposition, 1998-11, Vol.26 (11), p.1160

1998

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S-[2-(N7-guanyl)ethyl]glutathione, the major DNA adduct formed from 1,2-dibromoethane

Biochemistry (Easton), 1986-04, Vol.25 (8), p.2192-2198

1986

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Covalent binding of 1,2-dihaloalkanes to DNA and stability of the major DNA adduct, S-[2-(N7-guanyl)ethyl]glutathione

Cancer research (Chicago, Ill.), 1986-06, Vol.46 (6), p.2839-2844

1986

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Selectivity of rat and human glutathione S-transferases in activation of ethylene dibromide by glutathione conjugation and DNA binding and induction of unscheduled DNA synthesis in human hepatocytes

Cancer research (Chicago, Ill.), 1990-05, Vol.50 (9), p.2747-2752

1990

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Comparison of synthetic saponin cholesterol absorption inhibitors in rabbits: evidence for a non-stoichiometric, intestinal mechanism of action

Journal of lipid research, 1999-03, Vol.40 (3), p.464-474

1999

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Potent, Selective, and Systemically-Available Inhibitors of Acyl-Coenzyme A:Cholesterol Acyl Transferase (ACAT)

Journal of medicinal chemistry, 1994-04, Vol.37 (9), p.1252-1255

1994

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Pharmacokinetics of the Acyl Coenzyme A: Cholesterol Acyl Transferase Inhibitor CP-105,191 in Dogs-The Effect of Food and Sesame Oil on Systemic Exposure following Oral Dosing

Journal of pharmaceutical sciences, 1995-02, Vol.84 (2), p.131-133

1995

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Pharmacokinetics of the Aldose Reductase Inhibitor, Zopolrestat, in Humans

Journal of clinical pharmacology, 1994-07, Vol.34 (7), p.760-766

1994

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Glutathione-mediated binding of dibromoalkanes to DNA: specificity of rat glutathione-S-transferases and dibromoalkane structure

Carcinogenesis (New York), 1984-06, Vol.5 (6), p.805-808

1984

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Pharmacokinetics of zopolrestat, a carboxylic acid aldose reductase inhibitor, in normal and diabetic rats

Pharmaceutical research, 1991-12, Vol.8 (12), p.1511-1515

1991

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Activation of Dihaloalkanes by Glutathione Conjugation and Formation of DNA Adducts

Environmental health perspectives, 1987-12, Vol.76, p.15-18

1987

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Pharmacokinetics of Tiqueside (β‐Tigogenin Cellobioside) in Dogs, Rats, Rabbits, and Monkeys

Journal of pharmaceutical sciences, 1995-01, Vol.84 (1), p.12-14

1995

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Changes in metabolism of ram sperm associated with epididymal transit or induced by exogenous carnitine

Biology of reproduction, 1982-10, Vol.27 (3), p.735-743

1982

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Comparative tissue distribution and excretion of [1- 14C]acrylamide in beagle dogs and miniature pigs

Food and chemical toxicology, 1987-11, Vol.25 (11), p.871-875

1987

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Endogenous metabolism by sperm in response to altered cellular ATP requirements

Journal of cellular physiology, 1985-05, Vol.123 (2), p.180-190

1985

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Induction of Fluconazole Metabolism by Rifampin: In Vivo Study in Humans

Journal of clinical pharmacology, 1991-04, Vol.31 (4), p.358-361

1991

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Hydantoin bioisosteres. In vivo active spiro hydroxy acetic acid aldose reductase inhibitors

Journal of medicinal chemistry, 1992-06, Vol.35 (12), p.2169-2177

1992

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Alterations in motility and metabolism associated with sperm interaction with accessory sex gland fluids

Archives of biochemistry and biophysics, 1985-08, Vol.241 (1), p.1-9

1985

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Pharmacokinetics and pharmacodynamics of azithromycin in gerbils with haemophilus influenzae middle ear infection

Clinical pharmacology and therapeutics, 2005-02, Vol.77 (2), p.P89-P89

2005

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Metabolism and covalent binding of vic-dihaloalkanes, vinyl halides and acrylonitrile

IARC scientific publications, 1986 (70), p.255

1986

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A calorimetric method to assess endogenous metabolism and its application to the study of bovine sperm

Journal of biochemical and biophysical methods, 1983-01, Vol.7 (3), p.199-210

1983

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Pharmacokinetics and lung tissue concentrations of tulathromycin, a new triamilide antibiotic, in cattle

Veterinary therapeutics, 2004, Vol.5 (1), p.60

2004

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Tissue distribution and biotransformation of zopolrestat, an aldose reductase inhibitor, in rats

Pharmacological properties of a novel ACAT inhibitor (CP-113,818) in cholesterol-fed rats, hamsters, rabbits, and monkeys

Theoretical considerations on two equations for estimating the extent of absorption after oral administration of drugs

Bioavailability, multiple-dose pharmacokinetics, and biotransformation of the aldose reductase inhibitor zopolrestat in dogs

S-[2-(N7-guanyl)ethyl]glutathione, the major DNA adduct formed from 1,2-dibromoethane

Covalent binding of 1,2-dihaloalkanes to DNA and stability of the major DNA adduct, S-[2-(N7-guanyl)ethyl]glutathione

Selectivity of rat and human glutathione S-transferases in activation of ethylene dibromide by glutathione conjugation and DNA binding and induction of unscheduled DNA synthesis in human hepatocytes

Comparison of synthetic saponin cholesterol absorption inhibitors in rabbits: evidence for a non-stoichiometric, intestinal mechanism of action

Potent, Selective, and Systemically-Available Inhibitors of Acyl-Coenzyme A:Cholesterol Acyl Transferase (ACAT)

Pharmacokinetics of the Acyl Coenzyme A: Cholesterol Acyl Transferase Inhibitor CP-105,191 in Dogs-The Effect of Food and Sesame Oil on Systemic Exposure following Oral Dosing

Pharmacokinetics of the Aldose Reductase Inhibitor, Zopolrestat, in Humans

Glutathione-mediated binding of dibromoalkanes to DNA: specificity of rat glutathione-S-transferases and dibromoalkane structure

Pharmacokinetics of zopolrestat, a carboxylic acid aldose reductase inhibitor, in normal and diabetic rats

Activation of Dihaloalkanes by Glutathione Conjugation and Formation of DNA Adducts

Pharmacokinetics of Tiqueside (β‐Tigogenin Cellobioside) in Dogs, Rats, Rabbits, and Monkeys

Changes in metabolism of ram sperm associated with epididymal transit or induced by exogenous carnitine

Comparative tissue distribution and excretion of [1- 14C]acrylamide in beagle dogs and miniature pigs

Endogenous metabolism by sperm in response to altered cellular ATP requirements

Induction of Fluconazole Metabolism by Rifampin: In Vivo Study in Humans

Hydantoin bioisosteres. In vivo active spiro hydroxy acetic acid aldose reductase inhibitors

Alterations in motility and metabolism associated with sperm interaction with accessory sex gland fluids

Pharmacokinetics and pharmacodynamics of azithromycin in gerbils with haemophilus influenzae middle ear infection

Metabolism and covalent binding of vic-dihaloalkanes, vinyl halides and acrylonitrile

A calorimetric method to assess endogenous metabolism and its application to the study of bovine sperm

Pharmacokinetics and lung tissue concentrations of tulathromycin, a new triamilide antibiotic, in cattle

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