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Cyclic AMP is both a pro-apoptotic and anti-apoptotic second messenger

Acta Physiologica, 2012-02, Vol.204 (2), p.277-287

2012

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GPCR expression in tissues and cells: Are the optimal receptors being used as drug targets?

British journal of pharmacology, 2012-03, Vol.165 (6), p.1613-1616

2012

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G-protein-coupled receptor-signaling components in membrane raft and caveolae microdomains

Handbook of experimental pharmacology, 2008 (186), p.167

2008

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Genetic variations and polymorphisms of G protein-coupled receptors: functional and therapeutic implications

Annual review of pharmacology and toxicology, 2001-01, Vol.41 (1), p.593-624

2001

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Cyclic AMP/PKA-promoted apoptosis: insights from studies of S49 lymphoma cells

Hormone and metabolic research, 2014-11, Vol.46 (12), p.854-862

2014

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The Pro-apoptotic Protein Bim Is a Convergence Point for cAMP/Protein Kinase A- and Glucocorticoid-promoted Apoptosis of Lymphoid Cells

The Journal of biological chemistry, 2004-05, Vol.279 (20), p.20858-20865

2004

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Protein kinase C isozymes and the regulation of diverse cell responses

American journal of physiology. Lung cellular and molecular physiology, 2000-09, Vol.279 (3), p.429-L438

2000

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Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling

Cellular and molecular neurobiology, 2003-06, Vol.23 (3), p.305-314

2003

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Protein kinase C alpha mediates phospholipase D activation by nucleotides and phorbol ester in Madin-Darby canine kidney cells. Stimulation of phospholipase D is independent of activation of polyphosphoinositide-specific phospholipase C and phospholipase A2

The Journal of biological chemistry, 1994-04, Vol.269 (14), p.10511-10516

1994

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Distribution analysis of nonsynonymous polymorphisms within the G-protein-coupled receptor gene family

Genomics (San Diego, Calif.), 2003-03, Vol.81 (3), p.245-248

2003

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Retrovirally mediated transfer of a G protein-coupled receptor kinase (GRK) dominant-negative mutant enhances endogenous calcitonin receptor signaling in Chinese hamster ovary cells. GRK inhibition enhances expression of receptors and receptor mRNA

The Journal of biological chemistry, 2000-09, Vol.275 (38), p.29433-29440

2000

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Inhibition of Apoptosis in Normal and Transformed Intestinal Epithelial Cells by cAMP through Induction of Inhibitor of Apoptosis Protein (IAP)-2

Proceedings of the National Academy of Sciences - PNAS, 2003-07, Vol.100 (15), p.8921-8926

2003

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Do studies in caveolin‐knockouts teach us about physiology and pharmacology or instead, the ways mice compensate for ‘lost proteins’?

British journal of pharmacology, 2007-02, Vol.150 (3), p.251-254

2007

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Receptor Number and Caveolar Co-localization Determine Receptor Coupling Efficiency to Adenylyl Cyclase

The Journal of biological chemistry, 2001-11, Vol.276 (45), p.42063-42069

2001

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Phorbol ester and neomycin dissociate bradykinin receptor-mediated arachidonic acid release and polyphosphoinositide hydrolysis in Madin-Darby canine kidney cells. Evidence that bradykinin mediates noninterdependent activation of phospholipases A2 and C

The Journal of biological chemistry, 1988-10, Vol.263 (29), p.14640-14647

1988

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Quantification of signalling components and amplification in the beta-adrenergic-receptor-adenylate cyclase pathway in isolated adult rat ventricular myocytes

Biochemical journal, 1995-10, Vol.311 ( Pt 1) (1), p.75-80

1995

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Compartmentation of G-protein-coupled receptors and their signalling components in lipid rafts and caveolae

Biochemical Society transactions, 2005-11, Vol.33 (Pt 5), p.1131-1134

2005

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Key role for constitutive cyclooxygenase-2 of MDCK cells in basal signaling and response to released ATP

American Journal of Physiology: Cell Physiology, 2001-08, Vol.281 (2), p.C524-C531

2001

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Stoichiometry and compartmentation in G protein-coupled receptor signaling: implications for therapeutic interventions involving G(s)

The Journal of pharmacology and experimental therapeutics, 2000-08, Vol.294 (2), p.407

2000

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Cellular Release of and Response to ATP as Key Determinants of the Set-Point of Signal Transduction Pathways

The Journal of biological chemistry, 2000-04, Vol.275 (16), p.11735-11739

2000

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Stimulation of β -adrenergic Receptors of S49 Lymphoma Cells Redistributes the α Subunit of the Stimulatory G Protein between Cytosol and Membranes

Proceedings of the National Academy of Sciences - PNAS, 1989-10, Vol.86 (20), p.7900-7903

1989

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Heterogeneity of P2u- and P2y-purinergic receptor regulation of phospholipases in MDCK cells

American journal of physiology. Renal physiology, 1996-09, Vol.271 (3), p.610-F618

1996

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Therapeutic Oligonucleotides: State of the Art

Annual review of pharmacology and toxicology, 2019-01, Vol.59 (1), p.605-630

2019

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Inhibition of expression of protein kinase C alpha by antisense cDNA inhibits phorbol ester-mediated arachidonate release

The Journal of biological chemistry, 1993-06, Vol.268 (16), p.11946-11950

1993

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Alpha 1-adrenergic receptor-mediated phosphoinositide hydrolysis and prostaglandin E2 formation in Madin-Darby canine kidney cells. Possible parallel activation of phospholipase C and phospholipase A2

The Journal of biological chemistry, 1987-03, Vol.262 (9), p.4200-4207

1987

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Cyclic AMP is both a pro-apoptotic and anti-apoptotic second messenger

GPCR expression in tissues and cells: Are the optimal receptors being used as drug targets?

G-protein-coupled receptor-signaling components in membrane raft and caveolae microdomains

Genetic variations and polymorphisms of G protein-coupled receptors: functional and therapeutic implications

Cyclic AMP/PKA-promoted apoptosis: insights from studies of S49 lymphoma cells

The Pro-apoptotic Protein Bim Is a Convergence Point for cAMP/Protein Kinase A- and Glucocorticoid-promoted Apoptosis of Lymphoid Cells

Protein kinase C isozymes and the regulation of diverse cell responses

Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling

Protein kinase C alpha mediates phospholipase D activation by nucleotides and phorbol ester in Madin-Darby canine kidney cells. Stimulation of phospholipase D is independent of activation of polyphosphoinositide-specific phospholipase C and phospholipase A2

Distribution analysis of nonsynonymous polymorphisms within the G-protein-coupled receptor gene family

Retrovirally mediated transfer of a G protein-coupled receptor kinase (GRK) dominant-negative mutant enhances endogenous calcitonin receptor signaling in Chinese hamster ovary cells. GRK inhibition enhances expression of receptors and receptor mRNA

Inhibition of Apoptosis in Normal and Transformed Intestinal Epithelial Cells by cAMP through Induction of Inhibitor of Apoptosis Protein (IAP)-2

Do studies in caveolin‐knockouts teach us about physiology and pharmacology or instead, the ways mice compensate for ‘lost proteins’?

Receptor Number and Caveolar Co-localization Determine Receptor Coupling Efficiency to Adenylyl Cyclase

Phorbol ester and neomycin dissociate bradykinin receptor-mediated arachidonic acid release and polyphosphoinositide hydrolysis in Madin-Darby canine kidney cells. Evidence that bradykinin mediates noninterdependent activation of phospholipases A2 and C

Quantification of signalling components and amplification in the beta-adrenergic-receptor-adenylate cyclase pathway in isolated adult rat ventricular myocytes

Compartmentation of G-protein-coupled receptors and their signalling components in lipid rafts and caveolae

Key role for constitutive cyclooxygenase-2 of MDCK cells in basal signaling and response to released ATP

Stoichiometry and compartmentation in G protein-coupled receptor signaling: implications for therapeutic interventions involving G(s)

Cellular Release of and Response to ATP as Key Determinants of the Set-Point of Signal Transduction Pathways

Stimulation of β -adrenergic Receptors of S49 Lymphoma Cells Redistributes the α Subunit of the Stimulatory G Protein between Cytosol and Membranes

Heterogeneity of P2u- and P2y-purinergic receptor regulation of phospholipases in MDCK cells

Therapeutic Oligonucleotides: State of the Art

Inhibition of expression of protein kinase C alpha by antisense cDNA inhibits phorbol ester-mediated arachidonate release

Alpha 1-adrenergic receptor-mediated phosphoinositide hydrolysis and prostaglandin E2 formation in Madin-Darby canine kidney cells. Possible parallel activation of phospholipase C and phospholipase A2

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