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Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction

Cell stem cell, 2019-11, Vol.25 (5), p.713-727.e10

2019

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A systematic evaluation of the design and context dependencies of massively parallel reporter assays

Nature methods, 2020-11, Vol.17 (11), p.1083-1091

2020

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Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation

Nature communications, 2022-03, Vol.13 (1), p.1504-1504, Article 1504

2022

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Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution

Nature communications, 2019-08, Vol.10 (1), p.3583-15, Article 3583

2019

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A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity

Genome research, 2017-01, Vol.27 (1), p.38-52

2017

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lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements

Nature protocols, 2020-08, Vol.15 (8), p.2387-2412

2020

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Comprehensive network modeling approaches unravel dynamic enhancer-promoter interactions across neural differentiation

Genome Biology, 2024-08, Vol.25 (1), p.1-17

2024

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The cis -regulatory effects of modern human-specific variants

eLife, 2021-04, Vol.10

2021

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Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model

Nature genetics, 2013-09, Vol.45 (9), p.1021-1028

2013

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Transcription factor binding site orientation and order are major drivers of gene regulatory activity

Nature communications, 2023-04, Vol.14 (1), p.2333-2333, Article 2333

2023

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A Nosocomial Outbreak Caused by Human Rhinovirus Species A Type 61 in a Welfare Facility in Gunma Prefecture, Japan

Japanese Journal of Infectious Diseases, 2023/07/31, Vol.76(4), pp.263-265

2023

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Machine learning dissection of human accelerated regions in primate neurodevelopment

Neuron (Cambridge, Mass.), 2023-03, Vol.111 (6), p.857-873.e8

2023

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Decoding enhancers using massively parallel reporter assays

Genomics (San Diego, Calif.), 2015-09, Vol.106 (3), p.159-164

2015

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Characterization of De Novo Promoter Variants in Autism Spectrum Disorder with Massively Parallel Reporter Assays

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3509

2023

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Characterization of enhancer activity in early human neurodevelopment using Massively Parallel Reporter Assay (MPRA) and forebrain organoids

Scientific reports, 2024-02, Vol.14 (1), p.3936-12, Article 3936

2024

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Gbx2 Directly Restricts Otx2 Expression to Forebrain and Midbrain, Competing with Class III POU Factors

Molecular and Cellular Biology, 2012-07, Vol.32 (13), p.2618-2627

2012

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Effects of Fatty Acid Therapy in Addition to Strong Statin on Coronary Plaques in Acute Coronary Syndrome: An Optical Coherence Tomography Study

Journal of the American Heart Association, 2020-08, Vol.9 (16), p.e015593-e015593

2020

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Author Correction: lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements

Nature protocols, 2021-07, Vol.16 (7), p.3736-3736

2021

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High-throughput characterization of the role of non-B DNA motifs on promoter function

Cell genomics, 2022-04, Vol.2 (4), p.100111, Article 100111

2022

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Feeding interval and postprandial intestinal blood flow in premature infants

Pediatrics international, 2013-08, Vol.55 (4), p.472-476

2013

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Problems with using total serum bilirubin as a criterion for phototherapy in extremely low-birthweight infants

Pediatrics international, 2014-10, Vol.56 (5), p.731-734

2014

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Transcription of fgf8 is regulated by activating and repressive cis-elements at the midbrain–hindbrain boundary in zebrafish embryos

Developmental biology, 2008-04, Vol.316 (2), p.471-486

2008

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Statistical analysis of fatal bleeding pelvic fracture patients with severe associated injuries

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2008-01, Vol.13 (1), p.21-24

2008

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Evolutionary origin of the Otx2 enhancer for its expression in visceral endoderm

Developmental biology, 2010-06, Vol.342 (1), p.110-120

2010

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Optimizing sequence design strategies for perturbation MPRAs: a computational evaluation framework

Nucleic acids research, 2024-02, Vol.52 (4), p.1613-1627

2024

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Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction

A systematic evaluation of the design and context dependencies of massively parallel reporter assays

Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation

Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution

A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity

lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements

Comprehensive network modeling approaches unravel dynamic enhancer-promoter interactions across neural differentiation

The cis -regulatory effects of modern human-specific variants

Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model

Transcription factor binding site orientation and order are major drivers of gene regulatory activity

A Nosocomial Outbreak Caused by Human Rhinovirus Species A Type 61 in a Welfare Facility in Gunma Prefecture, Japan

Machine learning dissection of human accelerated regions in primate neurodevelopment

Decoding enhancers using massively parallel reporter assays

Characterization of De Novo Promoter Variants in Autism Spectrum Disorder with Massively Parallel Reporter Assays

Characterization of enhancer activity in early human neurodevelopment using Massively Parallel Reporter Assay (MPRA) and forebrain organoids

Gbx2 Directly Restricts Otx2 Expression to Forebrain and Midbrain, Competing with Class III POU Factors

Effects of Fatty Acid Therapy in Addition to Strong Statin on Coronary Plaques in Acute Coronary Syndrome: An Optical Coherence Tomography Study

Author Correction: lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements

High-throughput characterization of the role of non-B DNA motifs on promoter function

Feeding interval and postprandial intestinal blood flow in premature infants

Problems with using total serum bilirubin as a criterion for phototherapy in extremely low-birthweight infants

Transcription of fgf8 is regulated by activating and repressive cis-elements at the midbrain–hindbrain boundary in zebrafish embryos

Statistical analysis of fatal bleeding pelvic fracture patients with severe associated injuries

Evolutionary origin of the Otx2 enhancer for its expression in visceral endoderm

Optimizing sequence design strategies for perturbation MPRAs: a computational evaluation framework

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