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Fluorescent Derivatives of AC-42 To Probe Bitopic Orthosteric/Allosteric Binding Mechanisms on Muscarinic M1 Receptors

Journal of medicinal chemistry, 2012-03, Vol.55 (5), p.2125-2143

2012

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Pirenzepine Promotes the Dimerization of Muscarinic M1 Receptors through a Three-step Binding Process

The Journal of biological chemistry, 2009-07, Vol.284 (29), p.19533-19543

2009

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The Neurokinin A Receptor Activates Calcium and cAMP Responses through Distinct Conformational States

The Journal of biological chemistry, 2001-09, Vol.276 (37), p.34853-34861

2001

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On the Use of Nonfluorescent Dye Labeled Ligands in FRET-Based Receptor Binding Studies

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7847-7859

2005

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Fluorescence resonance energy transfer to probe human M1 muscarinic receptor structure and drug binding properties

Journal of neurochemistry, 2003-05, Vol.85 (3), p.768-778

2003

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Assessment of morphine-induced hyperalgesia and analgesic tolerance in mice using thermal and mechanical nociceptive modalities

Journal of visualized experiments, 2014-07 (89), p.e51264

2014

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RF-amide neuropeptides and their receptors in Mammals: Pharmacological properties, drug development and main physiological functions

Alimentary Pharmacology & Therapeutics (Suppl), 2016-04, Vol.160, p.84-132

2016

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Endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, modulate nociception and morphine analgesia via NPFF receptors

Neuropharmacology, 2013-12, Vol.75, p.164-171

2013

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Identification of an N -acylated- D Arg-Leu-NH 2 Dipeptide as a Highly Selective Neuropeptide FF1 Receptor Antagonist That Potently Prevents Opioid-Induced Hyperalgesia

Journal of medicinal chemistry, 2021-06, Vol.64 (11), p.7555-7564

2021

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Identification of an N‑acylated‑DArg-Leu-NH2 Dipeptide as a Highly Selective Neuropeptide FF1 Receptor Antagonist That Potently Prevents Opioid-Induced Hyperalgesia

Journal of medicinal chemistry, 2021-06, Vol.64 (11), p.7555-7564

2021

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Exploration of the orthosteric/allosteric interface in human M1 muscarinic receptors by bitopic fluorescent ligands

Molecular pharmacology, 2013-07, Vol.84 (1), p.71-85

2013

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Time-Resolved FRET Binding Assay to Investigate Hetero-Oligomer Binding Properties: Proof of Concept with Dopamine D1/D3 Heterodimer

ACS chemical biology, 2015-02, Vol.10 (2), p.466-474

2015

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G protein-coupled receptors: allosteric regulators of cell metabolism

M.S. Médecine sciences, 2012-10, Vol.28 (10), p.852

2012

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Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Journal of visualized experiments, 2014-07 (89)

2014

Volltextzugriff (PDF)

Fluorescent Pirenzepine Derivatives as Potential Bitopic Ligands of the Human M1 Muscarinic Receptor

Journal of medicinal chemistry, 2004-08, Vol.47 (17), p.4300-4315

2004

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Time-Resolved FRET Binding Assay to Investigate Hetero-Oligomer Binding Properties: Proof of Concept with Dopamine D 1 /D 3 Heterodimer

ACS chemical biology, 2015-02, Vol.10 (2), p.466-474

2015

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A Rapid and Versatile Method to Label Receptor Ligands Using “Click” Chemistry: Validation with the Muscarinic M1 Antagonist Pirenzepine

Bioconjugate chemistry, 2006-11, Vol.17 (6), p.1618-1623

2006

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Endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, modulate nociception and morphine analgesia via NPFF receptors

Neuropharmacology, 2013, Vol.75, p.164-171

2013

Volltextzugriff (PDF)

Pirenzepine Promotes the Dimerization of Muscarinic M1 Receptors through a Three-step Binding Process

The Journal of biological chemistry, 2009-05, Vol.284 (29), p.19533-19543

2009

Volltextzugriff (PDF)

Functional Characterization and Potential Applications for Enhanced Green Fluorescent Protein‐ and Epitope‐Fused Human M1 Muscarinic Receptors

Journal of neurochemistry, 1999-08, Vol.73 (2), p.791-801

1999

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Covalent labeling of muscarinic acetylcholine receptors by tritiated aryldiazonium photoprobes

Biochemical pharmacology, 1997-02, Vol.53 (4), p.501-510

1997

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Pharmacological and structural integrity of muscarinic M 2 acetylcholine receptors produced in Sf9 insect cells

European journal of pharmacology, 1997-08, Vol.333 (2), p.269-278

1997

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Pharmacological and structural integrity of muscarinic M2 acetylcholine receptors produced in Sf9 insect cells

European journal of pharmacology, 1997-08, Vol.333 (2-3), p.269-278

1997

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New photoaffinity labels for rat brain muscarinic acetylcholine receptors

Biochemical pharmacology, 1989-09, Vol.38 (17), p.2879-2887

1989

Volltextzugriff (PDF)

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RF313, an orally bioavailable neuropeptide FF receptor antagonist, opposes effects of RF-amide-related peptide-3 and opioid-induced hyperalgesia in rodents

Fluorescent Derivatives of AC-42 To Probe Bitopic Orthosteric/Allosteric Binding Mechanisms on Muscarinic M1 Receptors

Pirenzepine Promotes the Dimerization of Muscarinic M1 Receptors through a Three-step Binding Process

The Neurokinin A Receptor Activates Calcium and cAMP Responses through Distinct Conformational States

On the Use of Nonfluorescent Dye Labeled Ligands in FRET-Based Receptor Binding Studies

Fluorescence resonance energy transfer to probe human M1 muscarinic receptor structure and drug binding properties

Assessment of morphine-induced hyperalgesia and analgesic tolerance in mice using thermal and mechanical nociceptive modalities

RF-amide neuropeptides and their receptors in Mammals: Pharmacological properties, drug development and main physiological functions

Endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, modulate nociception and morphine analgesia via NPFF receptors

Identification of an N -acylated- D Arg-Leu-NH 2 Dipeptide as a Highly Selective Neuropeptide FF1 Receptor Antagonist That Potently Prevents Opioid-Induced Hyperalgesia

Identification of an N‑acylated‑DArg-Leu-NH2 Dipeptide as a Highly Selective Neuropeptide FF1 Receptor Antagonist That Potently Prevents Opioid-Induced Hyperalgesia

Exploration of the orthosteric/allosteric interface in human M1 muscarinic receptors by bitopic fluorescent ligands

Time-Resolved FRET Binding Assay to Investigate Hetero-Oligomer Binding Properties: Proof of Concept with Dopamine D1/D3 Heterodimer

G protein-coupled receptors: allosteric regulators of cell metabolism

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Fluorescent Pirenzepine Derivatives as Potential Bitopic Ligands of the Human M1 Muscarinic Receptor

Time-Resolved FRET Binding Assay to Investigate Hetero-Oligomer Binding Properties: Proof of Concept with Dopamine D 1 /D 3 Heterodimer

A Rapid and Versatile Method to Label Receptor Ligands Using “Click” Chemistry: Validation with the Muscarinic M1 Antagonist Pirenzepine

Endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, modulate nociception and morphine analgesia via NPFF receptors

Pirenzepine Promotes the Dimerization of Muscarinic M1 Receptors through a Three-step Binding Process

Functional Characterization and Potential Applications for Enhanced Green Fluorescent Protein‐ and Epitope‐Fused Human M1 Muscarinic Receptors

Covalent labeling of muscarinic acetylcholine receptors by tritiated aryldiazonium photoprobes

Pharmacological and structural integrity of muscarinic M 2 acetylcholine receptors produced in Sf9 insect cells

Pharmacological and structural integrity of muscarinic M2 acetylcholine receptors produced in Sf9 insect cells

New photoaffinity labels for rat brain muscarinic acetylcholine receptors

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