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Applications of bottom-up human artificial chromosomes in cell research and cell engineering

Experimental cell research, 2020-05, Vol.390 (1), p.111793-111793, Article 111793

2020

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A synthetic synaptic organizer protein restores glutamatergic neuronal circuits

Science (American Association for the Advancement of Science), 2020-08, Vol.369 (6507)

2020

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Inhibition of Transglutaminase 2 Reduces Peritoneal Injury in a Chlorhexidine-Induced Peritoneal Fibrosis Model

Laboratory investigation, 2023-04, Vol.103 (4), p.100050-100050, Article 100050

2023

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Endogenous chondroitin extends the lifespan and healthspan in C. elegans

Scientific reports, 2024-02, Vol.14 (1), p.4813-4813, Article 4813

2024

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Dicer is essential for formation of the heterochromatin structure in vertebrate cells

Nature cell biology, 2004-08, Vol.6 (8), p.784-791

2004

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Potent bystander effect and tumor tropism in suicide gene therapy using stem cells from human exfoliated deciduous teeth

Cancer gene therapy, 2023-01, Vol.30 (1), p.85-95

2023

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LINE1 family member is negative regulator of HLA-G expression

Nucleic acids research, 2012-11, Vol.40 (21), p.10742-10752

2012

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Construction and use of a bottom-up HAC vector for transgene expression

Methods in molecular biology (Clifton, N.J.), 2011-01, Vol.738, p.101

2011

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Human Artificial Chromosomes Constructed Using the Bottom-up Strategy Are Stably Maintained in Mitosis and Efficiently Transmissible to Progeny Mice

The Journal of biological chemistry, 2006-09, Vol.281 (36), p.26615-26623

2006

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Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP‐A chromatin of human cells

Genes to cells : devoted to molecular & cellular mechanisms, 2006-06, Vol.11 (6), p.673-684

2006

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Improving the efficiency of gene insertion in a human artificial chromosome vector and its transfer in human-induced pluripotent stem cells

Biology methods and protocols, 2018, Vol.3 (1), p.bpy013-bpy013

2018

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Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs

Chromosoma, 2015-03, Vol.124 (1), p.107-118

2015

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Construction of YAC-based mammalian artificial chromosomes

Nature biotechnology, 1998-05, Vol.16 (5), p.431-439

1998

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CENP-O, a protein localized at the centromere throughout the cell cycle, is a novel target antigen in systemic sclerosis

Journal of rheumatology, 2009-04, Vol.36 (4), p.781-786

2009

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Generation of human artificial chromosomes expressing naturally controlled guanosine triphosphate cyclohydrolase I gene

Genes to cells : devoted to molecular & cellular mechanisms, 2002-10, Vol.7 (10), p.1021-1032

2002

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Immortalized Hepatocytes Using Human Artificial Chromosome

Cell transplantation, 2008-01, Vol.17 (1-2), p.165-171

2008

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Cell to cell transfer of the chromatin-packaged human beta-globin gene cluster

Nucleic acids research, 2010-03, Vol.38 (5), p.e33-e33

2010

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Assay of centromere function using a human artificial chromosome

Chromosoma, 1998-12, Vol.107 (6-7), p.406-416

1998

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novel mouse model for Down syndrome that harbor a single copy of human artificial chromosome (HAC) carrying a limited number of genes from human chromosome 21

Transgenic research, 2014-04, Vol.23 (2), p.317-329

2014

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CBMS-3 Potent bystander effect in suicide gene therapy using genetically engineered stem cells from human exfoliated deciduous teeth

Neuro-oncology advances, 2021-12, Vol.3 (Supplement_6), p.vi2-vi2

2021

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Manipulating transgenes using a chromosome vector

Nucleic acids research, 2009-04, Vol.37 (6), p.e44-e44

2009

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Distribution of CENP-B boxes reflected in CREST centromere antigenic sites on long-range α-satellite DNA arrays of human chromosome 21

Human molecular genetics, 1994-08, Vol.3 (8), p.1245-1257

1994

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Genomic Organization, Chromosomal Localization, and the Complete 22 kb DNA Sequence of the Human GCMa/GCM1, a Placenta- Specific Transcription Factor Gene

Biochemical and biophysical research communications, 2000-11, Vol.278 (1), p.134-139

2000

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Mammalian centromere and artificial chromosome

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2004-09, Vol.49 (12), p.2011

2004

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Human Artificial Chromosomes

Genes & Genetic Systems, 1998, Vol.73 (6), p.469-469

1998

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Applications of bottom-up human artificial chromosomes in cell research and cell engineering

A synthetic synaptic organizer protein restores glutamatergic neuronal circuits

Inhibition of Transglutaminase 2 Reduces Peritoneal Injury in a Chlorhexidine-Induced Peritoneal Fibrosis Model

Endogenous chondroitin extends the lifespan and healthspan in C. elegans

Dicer is essential for formation of the heterochromatin structure in vertebrate cells

Potent bystander effect and tumor tropism in suicide gene therapy using stem cells from human exfoliated deciduous teeth

LINE1 family member is negative regulator of HLA-G expression

Construction and use of a bottom-up HAC vector for transgene expression

Human Artificial Chromosomes Constructed Using the Bottom-up Strategy Are Stably Maintained in Mitosis and Efficiently Transmissible to Progeny Mice

Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP‐A chromatin of human cells

Improving the efficiency of gene insertion in a human artificial chromosome vector and its transfer in human-induced pluripotent stem cells

Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs

Construction of YAC-based mammalian artificial chromosomes

CENP-O, a protein localized at the centromere throughout the cell cycle, is a novel target antigen in systemic sclerosis

Generation of human artificial chromosomes expressing naturally controlled guanosine triphosphate cyclohydrolase I gene

Immortalized Hepatocytes Using Human Artificial Chromosome

Cell to cell transfer of the chromatin-packaged human beta-globin gene cluster

Assay of centromere function using a human artificial chromosome

novel mouse model for Down syndrome that harbor a single copy of human artificial chromosome (HAC) carrying a limited number of genes from human chromosome 21

CBMS-3 Potent bystander effect in suicide gene therapy using genetically engineered stem cells from human exfoliated deciduous teeth

Manipulating transgenes using a chromosome vector

Distribution of CENP-B boxes reflected in CREST centromere antigenic sites on long-range α-satellite DNA arrays of human chromosome 21

Genomic Organization, Chromosomal Localization, and the Complete 22 kb DNA Sequence of the Human GCMa/GCM1, a Placenta- Specific Transcription Factor Gene

Mammalian centromere and artificial chromosome

Human Artificial Chromosomes

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