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Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors

Scientific reports, 2022-12, Vol.12 (1), p.21534-21534, Article 21534

2022

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Papyrus: a large-scale curated dataset aimed at bioactivity predictions

Journal of cheminformatics, 2023-01, Vol.15 (1), p.3-3, Article 3

2023

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Kv11.1 (hERG)‐induced cardiotoxicity: a molecular insight from a binding kinetics study of prototypical Kv11.1 (hERG) inhibitors

British journal of pharmacology, 2015-02, Vol.172 (3), p.940-955

2015

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International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors

Pharmacological reviews, 2001-12, Vol.53 (4), p.527

2001

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Small molecule absorption by PDMS in the context of drug response bioassays

Biochemical and biophysical research communications, 2017-01, Vol.482 (2), p.323-328

2017

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Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation

Trends in pharmacological sciences (Regular ed.), 2011-01, Vol.32 (1), p.35-42

2011

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Structure‐activity relationships of pentamidine‐affected ion channel trafficking and dofetilide mediated rescue

British journal of pharmacology, 2013-07, Vol.169 (6), p.1322-1334

2013

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Interleukin-6 Upregulates Neuronal Adenosine A1 Receptors : Implications for Neuromodulation and Neuroprotection

Neuropsychopharmacology (New York, N.Y.), 2008-08, Vol.33 (9), p.2237-2250

2008

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Pyrazole Derivatives as Partial Agonists for the Nicotinic Acid Receptor

Journal of medicinal chemistry, 2003-08, Vol.46 (18), p.3945-3951

2003

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Inverse agonism at G protein‐coupled receptors: (patho)physiological relevance and implications for drug discovery

British journal of pharmacology, 2000-05, Vol.130 (1), p.1-12

2000

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Role of ceramide 1 in the molecular organization of the stratum corneum lipids

Journal of lipid research, 1998-01, Vol.39 (1), p.186-196

1998

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Impact of cancer-associated mutations in CC chemokine receptor 2 on receptor function and antagonism

Biochemical pharmacology, 2023-02, Vol.208, p.115399-115399, Article 115399

2023

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Kinetic binding and activation profiles of endogenous tachykinins targeting the NK1 receptor

Biochemical pharmacology, 2016-10, Vol.118, p.88-95

2016

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Structure–activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A)

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (9), p.2736-2739

2011

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Persistent GnRH receptor activation in pituitary αT3-1 cells analyzed with a label-free technology

Biosensors & bioelectronics, 2016-05, Vol.79, p.721-727

2016

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Thiazole and Thiadiazole Analogues as a Novel Class of Adenosine Receptor Antagonists

Journal of medicinal chemistry, 2001-03, Vol.44 (5), p.749-762

2001

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The role of the second and third extracellular loops of the adenosine A1 receptor in activation and allosteric modulation

Biochemical pharmacology, 2012-07, Vol.84 (1), p.76-87

2012

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Correlation between human ether‐a‐go‐go‐related gene channel inhibition and action potential prolongation

British journal of pharmacology, 2017-09, Vol.174 (18), p.3081-3093

2017

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Suramin analogues as subtype-selective G protein inhibitors

Molecular pharmacology, 1996-04, Vol.49 (4), p.602-611

1996

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Getting personal: Endogenous adenosine receptor signaling in lymphoblastoid cell lines

Biochemical pharmacology, 2016-09, Vol.115, p.114-122

2016

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A binding site model and structure-activity relationships for the rat A3 adenosine receptor

Molecular pharmacology, 1994-06, Vol.45 (6), p.1101-1111

1994

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Mass spectrometry-based ligand binding assays on adenosine A1 and A2A receptors

Purinergic signalling, 2015-12, Vol.11 (4), p.581-594

2015

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Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto‐ATPase

British journal of pharmacology, 1995-01, Vol.114 (2), p.475-481

1995

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Isolation of Opioid-active Compounds from Tabernaemontana pachysiphon leaves

Journal of pharmacy and pharmacology, 1999-12, Vol.51 (12), p.1441-1446

1999

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Design and synthesis of novel small molecule CCR2 antagonists: Evaluation of 4-aminopiperidine derivatives

Bioorganic & medicinal chemistry letters, 2014-12, Vol.24 (23), p.5377-5380

2014

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Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors

Papyrus: a large-scale curated dataset aimed at bioactivity predictions

Kv11.1 (hERG)‐induced cardiotoxicity: a molecular insight from a binding kinetics study of prototypical Kv11.1 (hERG) inhibitors

International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors

Small molecule absorption by PDMS in the context of drug response bioassays

Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation

Structure‐activity relationships of pentamidine‐affected ion channel trafficking and dofetilide mediated rescue

Interleukin-6 Upregulates Neuronal Adenosine A1 Receptors : Implications for Neuromodulation and Neuroprotection

Pyrazole Derivatives as Partial Agonists for the Nicotinic Acid Receptor

Inverse agonism at G protein‐coupled receptors: (patho)physiological relevance and implications for drug discovery

Role of ceramide 1 in the molecular organization of the stratum corneum lipids

Impact of cancer-associated mutations in CC chemokine receptor 2 on receptor function and antagonism

Kinetic binding and activation profiles of endogenous tachykinins targeting the NK1 receptor

Structure–activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A)

Persistent GnRH receptor activation in pituitary αT3-1 cells analyzed with a label-free technology

Thiazole and Thiadiazole Analogues as a Novel Class of Adenosine Receptor Antagonists

The role of the second and third extracellular loops of the adenosine A1 receptor in activation and allosteric modulation

Correlation between human ether‐a‐go‐go‐related gene channel inhibition and action potential prolongation

Suramin analogues as subtype-selective G protein inhibitors

Getting personal: Endogenous adenosine receptor signaling in lymphoblastoid cell lines

A binding site model and structure-activity relationships for the rat A3 adenosine receptor

Mass spectrometry-based ligand binding assays on adenosine A1 and A2A receptors

Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto‐ATPase

Isolation of Opioid-active Compounds from Tabernaemontana pachysiphon leaves

Design and synthesis of novel small molecule CCR2 antagonists: Evaluation of 4-aminopiperidine derivatives

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