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Identification of the dog orthologue of human MAS-related G protein coupled receptor X2 (MRGPRX2) essential for drug-induced pseudo-allergic reactions

Scientific reports, 2020-09, Vol.10 (1), p.16146, Article 16146

2020

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A Novel HER3-Targeting Antibody-Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization

Clinical cancer research, 2019-12, Vol.25 (23), p.7151-7161

2019

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Outer retinal involvement in N-methyl-D-aspartate-induced inner retinal injury in rabbits assessed by optical coherence tomography

The Journal of Toxicological Sciences, 2020, Vol.45(5), pp.261-269

2020

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Circulating liver-specific microRNAs in cynomolgus monkeys

Journal of Toxicologic Pathology, 2018, Vol.31(1), pp.3-13

2018

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Wide application of a novel topoisomerase I inhibitor-based drug conjugation technology

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (20), p.5069-5072

2016

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Protein overexpression by adeno-associated virus-based gene therapy products in cardiomyocytes induces endoplasmic reticulum stress and myocardial degeneration in mice

Journal of Toxicologic Pathology, 2024, pp.2024-0011

2024

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MicroRNA profiles in a monkey testicular injury model induced by testicular hyperthermia

Journal of applied toxicology, 2016-12, Vol.36 (12), p.1614-1621

2016

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Absolute Quantification of Plasma MicroRNA Levels in Cynomolgus Monkeys, Using Quantitative Real-time Reverse Transcription PCR

Journal of visualized experiments, 2018-02 (132)

2018

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Comprehensive Analysis of Circulating microRNA Specific to the Liver, Heart, and Skeletal Muscle of Cynomolgus Monkeys

International journal of toxicology, 2017-05, Vol.36 (3), p.220-228

2017

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Comprehensive analysis of cardiac function, blood biomarkers and histopathology for milrinone-induced cardiotoxicity in cynomolgus monkeys

Journal of pharmacological and toxicological methods, 2020-05, Vol.103, p.106870, Article 106870

2020

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A monkey model of acetaminophen-induced hepatotoxicity; phenotypic similarity to human

The Journal of Toxicological Sciences, 2017/02/01, Vol.42(1), pp.73-84

2017

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Gene expression analysis of Arc mRNA as a neuronal cell activity marker in the hippocampus and amygdala in two-way active avoidance test in rats

Journal of pharmacological and toxicological methods, 2017-11, Vol.88 (Pt 2), p.140-146

2017

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MicroRNA profiling in ethylene glycol monomethyl ether-induced monkey testicular toxicity model

Journal of toxicological sciences, 2015-06, Vol.40 (3), p.375-382

2015

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MicroRNA profling in ethylene glycol monomethyl ether-induced monkey testicular toxicity model

The Journal of Toxicological Sciences, 2015/06/01, Vol.40(3), pp.375-382

2015

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En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH

Cell, 2022-10, Vol.185 (22), p.4216-4232.e16

2022

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Plasma citrulline is a sensitive safety biomarker for small intestinal injury in rats

Toxicology letters, 2018-10, Vol.295, p.416-423

2018

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Hedgehog signaling through GLI1 and GLI2 is required for epithelial–mesenchymal transition in human trophoblasts

Biochimica et biophysica acta, 2015-07, Vol.1850 (7), p.1438-1448

2015

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Fluoroquinolones suppress gluconeogenesis by inhibiting fructose 1,6-bisphosphatase in primary monkey hepatocytes

Toxicology in vitro, 2020-06, Vol.65, p.104786-104786, Article 104786

2020

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Establishment of an in vitro cytotoxicity assay platform using primary monkey cardiomyocytes

Toxicology in vitro, 2019-02, Vol.54, p.130-136

2019

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Hedgehog signaling stimulates the conversion of cholesterol to steroids

Cellular signalling, 2015-03, Vol.27 (3), p.487-497

2015

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UNC569-induced Morphological Changes in Pigment Epithelia and Photoreceptor Cells in the Retina through MerTK Inhibition in Mice

Toxicologic pathology, 2018-02, Vol.46 (2), p.193-201

2018

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Absolute Quantification of Plasma MicroRNA Levels in Cynomolgus Monkeys, Using Quantitative Real-time Reverse Transcription PCR

Journal of visualized experiments, 2018-02 (132)

2018

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DS-7250, a Diacylglycerol Acyltransferase 1 Inhibitor, Enhances Hepatic Steatosis in Zucker Fatty Rats via Upregulation of Fatty Acid Synthesis

Toxicologic pathology, 2018-04, Vol.46 (3), p.302-311

2018

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Abstract 5181: Therapeutic targeting of GPR20, selectively expressed in gastrointestinal stromal tumor (GIST), with DS-6157a, an antibody-drug conjugate (ADC)

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5181-5181

2020

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Identification of the dog orthologue of human MAS-related G protein coupled receptor X2 (MRGPRX2) essential for drug-induced pseudo-allergic reactions

A Novel HER3-Targeting Antibody-Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization

Outer retinal involvement in N-methyl-D-aspartate-induced inner retinal injury in rabbits assessed by optical coherence tomography

Circulating liver-specific microRNAs in cynomolgus monkeys

Wide application of a novel topoisomerase I inhibitor-based drug conjugation technology

Protein overexpression by adeno-associated virus-based gene therapy products in cardiomyocytes induces endoplasmic reticulum stress and myocardial degeneration in mice

MicroRNA profiles in a monkey testicular injury model induced by testicular hyperthermia

Absolute Quantification of Plasma MicroRNA Levels in Cynomolgus Monkeys, Using Quantitative Real-time Reverse Transcription PCR

Comprehensive Analysis of Circulating microRNA Specific to the Liver, Heart, and Skeletal Muscle of Cynomolgus Monkeys

Comprehensive analysis of cardiac function, blood biomarkers and histopathology for milrinone-induced cardiotoxicity in cynomolgus monkeys

A monkey model of acetaminophen-induced hepatotoxicity; phenotypic similarity to human

Gene expression analysis of Arc mRNA as a neuronal cell activity marker in the hippocampus and amygdala in two-way active avoidance test in rats

MicroRNA profiling in ethylene glycol monomethyl ether-induced monkey testicular toxicity model

MicroRNA profling in ethylene glycol monomethyl ether-induced monkey testicular toxicity model

En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH

Plasma citrulline is a sensitive safety biomarker for small intestinal injury in rats

Hedgehog signaling through GLI1 and GLI2 is required for epithelial–mesenchymal transition in human trophoblasts

Fluoroquinolones suppress gluconeogenesis by inhibiting fructose 1,6-bisphosphatase in primary monkey hepatocytes

Establishment of an in vitro cytotoxicity assay platform using primary monkey cardiomyocytes

Hedgehog signaling stimulates the conversion of cholesterol to steroids

UNC569-induced Morphological Changes in Pigment Epithelia and Photoreceptor Cells in the Retina through MerTK Inhibition in Mice

Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody-Drug Conjugate

Absolute Quantification of Plasma MicroRNA Levels in Cynomolgus Monkeys, Using Quantitative Real-time Reverse Transcription PCR

DS-7250, a Diacylglycerol Acyltransferase 1 Inhibitor, Enhances Hepatic Steatosis in Zucker Fatty Rats via Upregulation of Fatty Acid Synthesis

Abstract 5181: Therapeutic targeting of GPR20, selectively expressed in gastrointestinal stromal tumor (GIST), with DS-6157a, an antibody-drug conjugate (ADC)

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