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Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Nature communications, 2022-02, Vol.13 (1), p.770-770, Article 770

2022

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Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice

The Journal of biological chemistry, 2018-09, Vol.293 (38), p.14689-14706

2018

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The effects of diet on occlusive coronary artery atherosclerosis and myocardial infarction in scavenger receptor class B, type 1/low-density lipoprotein receptor double knockout mice

Arteriosclerosis, thrombosis, and vascular biology, 2014-11, Vol.34 (11), p.2394-2403

2014

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Miglustat as a therapeutic agent: prospects and caveats

Journal of Medical Genetics, 2012-09, Vol.49 (9), p.591-597

2012

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Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice

JHEP reports, 2019-12, Vol.1 (6), p.418-429

2019

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Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium

Frontiers in physiology, 2023-01, Vol.13, p.1023397-1023397

2023

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Neuraminidase 4 (NEU4): new biological and physiological player

Glycobiology (Oxford), 2023-04, Vol.33 (3), p.182-187

2023

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Hypomorphic sialidase expression decreases serum cholesterol by downregulation of VLDL production in mice

Journal of lipid research, 2012-12, Vol.53 (12), p.2573-2585

2012

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SR-BI in bone marrow derived cells protects mice from diet induced coronary artery atherosclerosis and myocardial infarction

PloS one, 2013-08, Vol.8 (8), p.e72492-e72492

2013

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The therapeutic potential of pharmacological chaperones and proteosomal inhibitors, Celastrol and MG132 in the treatment of sialidosis

Molecular genetics and metabolism, 2012-09, Vol.107 (1-2), p.173-185

2012

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Asialoglycoprotein receptors as important mediators of plasma lipids and atherosclerosis

Current opinion in lipidology, 2017-04, Vol.28 (2), p.209-212

Igdoura, Suleiman A

2017

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Characterization of Proliferating Lesion‐Resident Cells During All Stages of Atherosclerotic Growth

Journal of the American Heart Association, 2016-08, Vol.5 (8), p.n/a

2016

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Lysosomal and Proteasomal Degradation Play Distinct Roles in the Life Cycle of Cx43 in Gap Junctional Intercellular Communication-deficient and -competent Breast Tumor Cells

The Journal of biological chemistry, 2003-08, Vol.278 (32), p.30005-30014

2003

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GDF10 is a negative regulator of vascular calcification

The Journal of biological chemistry, 2024-11, Vol.300 (11), p.107805, Article 107805

2024

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Restoration of the ER stress response protein TDAG51 in hepatocytes mitigates NAFLD in mice

The Journal of biological chemistry, 2024-02, Vol.300 (2), p.105655-105655, Article 105655

2024

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Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained

The Journal of biological chemistry, 2018-05, Vol.293 (19), p.7329-7343

2018

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The effect of pomegranate extract on coronary artery atherosclerosis in SR-BI/APOE double knockout mice

Atherosclerosis, 2013-05, Vol.228 (1), p.80-89

2013

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TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells

Arteriosclerosis, thrombosis, and vascular biology, 2020-07, Vol.40 (7), p.1664-1679

2020

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Suppression of NK and CD8 + T cells reduces astrogliosis but accelerates cerebellar dysfunction and shortens life span in a mouse model of Sandhoff disease

Journal of neuroimmunology, 2017-05, Vol.306, p.55-67

2017

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Bi-phasic gliosis drives neuropathology in a Sandhoff disease mouse model

Journal of neuroimmunology, 2016-10, Vol.299, p.19-27

2016

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Neuronal pentraxin 1 depletion delays neurodegeneration and extends life in Sandhoff disease mice

Human molecular genetics, 2017-02, Vol.26 (4), p.661-673

2017

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Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice

Human molecular genetics, 2013-10, Vol.22 (19), p.3960-3975

2013

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Overexpression of MyoD-inducible lysosomal sialidase (neu1) inhibits myogenesis in C2C12 cells

Experimental cell research, 2005-11, Vol.311 (1), p.157-166

2005

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Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity

Kidney360, 2022-08, Vol.3 (8), p.1394-1410

2022

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A new method for the purification of bioviable NEU1 sialidase for enzyme replacement therapy for sialidosis

Molecular genetics and metabolism, 2024-02, Vol.141 (2), p.107892, Article 107892

2024

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Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice

The effects of diet on occlusive coronary artery atherosclerosis and myocardial infarction in scavenger receptor class B, type 1/low-density lipoprotein receptor double knockout mice

Miglustat as a therapeutic agent: prospects and caveats

Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice

Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium

Neuraminidase 4 (NEU4): new biological and physiological player

Hypomorphic sialidase expression decreases serum cholesterol by downregulation of VLDL production in mice

SR-BI in bone marrow derived cells protects mice from diet induced coronary artery atherosclerosis and myocardial infarction

The therapeutic potential of pharmacological chaperones and proteosomal inhibitors, Celastrol and MG132 in the treatment of sialidosis

Asialoglycoprotein receptors as important mediators of plasma lipids and atherosclerosis

Characterization of Proliferating Lesion‐Resident Cells During All Stages of Atherosclerotic Growth

Lysosomal and Proteasomal Degradation Play Distinct Roles in the Life Cycle of Cx43 in Gap Junctional Intercellular Communication-deficient and -competent Breast Tumor Cells

GDF10 is a negative regulator of vascular calcification

Restoration of the ER stress response protein TDAG51 in hepatocytes mitigates NAFLD in mice

Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained

The effect of pomegranate extract on coronary artery atherosclerosis in SR-BI/APOE double knockout mice

TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells

Suppression of NK and CD8 + T cells reduces astrogliosis but accelerates cerebellar dysfunction and shortens life span in a mouse model of Sandhoff disease

Bi-phasic gliosis drives neuropathology in a Sandhoff disease mouse model

Neuronal pentraxin 1 depletion delays neurodegeneration and extends life in Sandhoff disease mice

Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice

Overexpression of MyoD-inducible lysosomal sialidase (neu1) inhibits myogenesis in C2C12 cells

Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity

A new method for the purification of bioviable NEU1 sialidase for enzyme replacement therapy for sialidosis

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