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Clarification of the Mechanism of Clopidogrel-Mediated Drug-Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information

Drug metabolism and disposition, 2016-10, Vol.44 (10), p.1622-1632

2016

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Pharmacogenetic Characterization of Sulfasalazine Disposition Based on NAT2 and ABCG2 (BCRP) Gene Polymorphisms in Humans

Clinical pharmacology and therapeutics, 2008-07, Vol.84 (1), p.95-103

2008

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SLCO1B1 (OATP1B1, an Uptake Transporter) and ABCG2 (BCRP, an Efflux Transporter) Variant Alleles and Pharmacokinetics of Pitavastatin in Healthy Volunteers

Clinical pharmacology and therapeutics, 2007-11, Vol.82 (5), p.541-547

2007

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Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril

Clinical pharmacology and therapeutics, 2006-05, Vol.79 (5), p.427-439

2006

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Effects of multiple-dose rifampicin 450 mg on the pharmacokinetics of fexofenadine enantiomers in Japanese volunteers

Journal of clinical pharmacy and therapeutics, 2015-02, Vol.40 (1), p.98-103

2015

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The effects of genetic polymorphisms of CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy : Studies in stereoselective hydroxylation and population pharmacokinetics

Epilepsia (Copenhagen), 1998-12, Vol.39 (12), p.1317-1323

1998

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Comparison of the kinetic disposition of and serum gastrin change by lansoprazole versus rabeprazole during an 8-day dosing scheme in relation to CYP2C19 polymorphism

European journal of clinical pharmacology, 2001-09, Vol.57 (6-7), p.485-492

2001

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Genetic polymorphism of cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese population

Therapeutic drug monitoring, 1998-06, Vol.20 (3), p.243-247

1998

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Influence of common variants in the pharmacokinetic genes ( OATP-C, UGT1A1, and MRP2) on serum bilirubin levels in healthy subjects

Hepatology research, 2004-10, Vol.30 (2), p.91-95

2004

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Hirschsprung's Disease and the Allied Disorders: Status Quo and Future Prospects of Treatment

1st ed. 2019., 2019

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The association of tobacco use with prescription of muscle relaxants, benzodiazepines, and opioid analgesics for non‐cancer pain

The American journal on addictions, 2019-03, Vol.28 (2), p.63-70

2019

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CYP2C19 polymorphism effect on phenobarbitone : Pharmacokineties in Japanese patients with epilepsy : analysis by population pharmacokinetics

European journal of clinical pharmacology, 2000-03, Vol.55 (11-12), p.821-825

2000

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Effects of Stroke Education of Junior High School Students on Stroke Knowledge of Their Parents: Tochigi Project

Stroke (1970), 2015-02, Vol.46 (2), p.572-574

2015

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Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene

The Journal of pharmacology and experimental therapeutics, 2001-06, Vol.297 (3), p.1137

2001

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Lack of differences in diclofenac (a substrate for CYP2C9) pharmacokinetics in healthy volunteers with respect to the single CYP2C93 allele

European journal of clinical pharmacology, 2000-04, Vol.56 (1), p.65-68

2000

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The MDR1 (ABCB1) gene polymorphism and its clinical implications

Clinical pharmacokinetics, 2004-01, Vol.43 (9), p.553-576

2004

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Evaluation of k2 imaging algorithm with 11C-verapamil using clustering-based kinetic approach

NeuroImage (Orlando, Fla.), 2008, Vol.41, p.T68-T68

2008

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A CYP2D6 phenotype-genotype mismatch in Japanese psychiatric patients

Pharmacopsychiatry, 2004-05, Vol.36 (5), p.192-196

2004

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Psychotropic Drug―Drug Interactions Involving P-Glycoprotein

CNS drugs, 2012-11, Vol.26 (11), p.959-973

2012

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Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene

Transplantation, 2002-08, Vol.74 (4), p.571

2002

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SLCO1B1 polymorphisms affect atorvastatin pharmacokinetics and cholesterol-lowering effects in patients with hypercholesterolemia in a microdosing approach

European heart journal, 2013-08, Vol.34 (suppl 1), p.140-140

2013

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Comparison of pharmacokinetics, pharmacodynamics, safety, and tolerability of the amyloid β monoclonal antibody solanezumab in Japanese and white patients with mild to moderate alzheimer disease

Clinical neuropharmacology, 2012-01, Vol.35 (1), p.25-29

2012

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Modeling and simulation of bone mineral density response from a phase 2 study of ONO-5334, a new cathepsin K inhibitor, to support dose selection in osteoporosis

Journal of clinical pharmacology, 2014-08, Vol.54 (8), p.937-948

2014

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Stereoselective 4′‐hydroxylation of phenytoin: relationship to (S)‐mephenytoin polymorphism in Japanese

British journal of clinical pharmacology, 1997-04, Vol.43 (4), p.441-445

1997

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Population pharmacokinetic and pharmacodynamic modeling of different formulations of ONO-5334, cathepsin K inhibitor, in Caucasian and Japanese postmenopausal females

Journal of clinical pharmacology, 2014-01, Vol.54 (1), p.23-34

2014

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Clarification of the Mechanism of Clopidogrel-Mediated Drug-Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information

Pharmacogenetic Characterization of Sulfasalazine Disposition Based on NAT2 and ABCG2 (BCRP) Gene Polymorphisms in Humans

SLCO1B1 (OATP1B1, an Uptake Transporter) and ABCG2 (BCRP, an Efflux Transporter) Variant Alleles and Pharmacokinetics of Pitavastatin in Healthy Volunteers

Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril

Effects of multiple-dose rifampicin 450 mg on the pharmacokinetics of fexofenadine enantiomers in Japanese volunteers

The effects of genetic polymorphisms of CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy : Studies in stereoselective hydroxylation and population pharmacokinetics

Comparison of the kinetic disposition of and serum gastrin change by lansoprazole versus rabeprazole during an 8-day dosing scheme in relation to CYP2C19 polymorphism

Genetic polymorphism of cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese population

Influence of common variants in the pharmacokinetic genes ( OATP-C, UGT1A1, and MRP2) on serum bilirubin levels in healthy subjects

Hirschsprung's Disease and the Allied Disorders: Status Quo and Future Prospects of Treatment

The association of tobacco use with prescription of muscle relaxants, benzodiazepines, and opioid analgesics for non‐cancer pain

CYP2C19 polymorphism effect on phenobarbitone : Pharmacokineties in Japanese patients with epilepsy : analysis by population pharmacokinetics

Effects of Stroke Education of Junior High School Students on Stroke Knowledge of Their Parents: Tochigi Project

Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene

Lack of differences in diclofenac (a substrate for CYP2C9) pharmacokinetics in healthy volunteers with respect to the single CYP2C93 allele

The MDR1 (ABCB1) gene polymorphism and its clinical implications

Evaluation of k2 imaging algorithm with 11C-verapamil using clustering-based kinetic approach

A CYP2D6 phenotype-genotype mismatch in Japanese psychiatric patients

Psychotropic Drug―Drug Interactions Involving P-Glycoprotein

Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene

SLCO1B1 polymorphisms affect atorvastatin pharmacokinetics and cholesterol-lowering effects in patients with hypercholesterolemia in a microdosing approach

Comparison of pharmacokinetics, pharmacodynamics, safety, and tolerability of the amyloid β monoclonal antibody solanezumab in Japanese and white patients with mild to moderate alzheimer disease

Modeling and simulation of bone mineral density response from a phase 2 study of ONO-5334, a new cathepsin K inhibitor, to support dose selection in osteoporosis

Stereoselective 4′‐hydroxylation of phenytoin: relationship to (S)‐mephenytoin polymorphism in Japanese

Population pharmacokinetic and pharmacodynamic modeling of different formulations of ONO-5334, cathepsin K inhibitor, in Caucasian and Japanese postmenopausal females

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