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Nitrosamine Reactivity: A Survey of Reactions and Purge Processes

Organic process research & development, 2021-08, Vol.25 (8), p.1788-1801

2021

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Annulation of Thioimidates and Vinyl Carbodiimides to Prepare 2-Aminopyrimidines, Competent Nucleophiles for Intramolecular Alkyne Hydroamination. Synthesis of (−)-Crambidine

Journal of the American Chemical Society, 2010-02, Vol.132 (6), p.1802-1803

2010

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Aziridine-2-carboxylic Acid-Containing Peptides: Application to Solution- and Solid-Phase Convergent Site-Selective Peptide Modification

Journal of the American Chemical Society, 2005-05, Vol.127 (20), p.7359-7369

2005

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Synthesis of ABBV-168, a 2′-Bromouridine for the Treatment of Hepatitis C

Journal of organic chemistry, 2019-04, Vol.84 (8), p.4723-4734

2019

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Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated SNAr Coupling

Organic process research & development, 2016-07, Vol.20 (7), p.1191-1202

2016

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Risk Assessment of the Leachables’ Profile for Small-Molecule Pharmaceutical Drug Substances

Organic process research & development, 2021-12, Vol.25 (12), p.2693-2706

2021

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New Semi-Automated Computer-Based System for Assessing the Purge of Mutagenic Impurities

Organic process research & development, 2019-11, Vol.23 (11), p.2470-2481

2019

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A consortium-driven framework to guide the implementation of ICH M7 Option 4 control strategies

Regulatory toxicology and pharmacology, 2017-11, Vol.90, p.22-28

2017

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Palbociclib Commercial Manufacturing Process Development. Part II: Regioselective Heck Coupling with Polymorph Control for Processability

Organic process research & development, 2016-07, Vol.20 (7), p.1203-1216

2016

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Palbociclib Commercial Manufacturing Process Development. Part III. Deprotection Followed by Crystallization for API Particle Property Control

Organic process research & development, 2016-07, Vol.20 (7), p.1217-1226

2016

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Development of a Practical and Convergent Process for the Preparation of Sulopenem

Organic process research & development, 2012-08, Vol.16 (8), p.1348-1359

2012

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Synthesis of Filibuvir. Part III. Development of a Process for the Reductive Coupling of an Aldehyde and a β‑Keto-lactone

Organic process research & development, 2014-01, Vol.18 (1), p.45-56

2014

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Development of a Practical and Efficient Synthesis of Chloromethyl 2-Ethoxy-2-methylpropanoate

Organic process research & development, 2010-11, Vol.14 (6), p.1402-1406

2010

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Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated S N Ar Coupling

Organic process research & development, 2016-07, Vol.20 (7), p.1191-1202

2016

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Selected Free Radical Reactions

Practical Synthetic Organic Chemistry, 2020, p.563-589

2020

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Statistical tools to aid in the assessment of critical process parameters

Pharmaceutical technology Europe, 2016-03, Vol.28 (3), p.22

2016

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Reductions

Practical Synthetic Organic Chemistry, 2020, p.455-511

2020

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Selected Catalytic Reactions

Practical Synthetic Organic Chemistry, 2020, p.269-375

2020

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Palbociclib (Ibrance): The First‐in‐Class CDK4/6 Inhibitor for Breast Cancer

Innovative Drug Synthesis, 2015, p.167-196

2015

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Selected Free Radical Reactions

Practical Synthetic Organic Chemistry, 2011, p.557-574

2011

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Conjugation of Selenols with Aziridine-2-Carboxylic Acid-Containing Peptides

Synlett, 2005-08, Vol.2005 (13), p.2011-2014

2005

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Selected Metal-Mediated Cross-Coupling Reactions

Practical Synthetic Organic Chemistry, 2011, p.279-340

2011

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Reductions

Practical Synthetic Organic Chemistry, 2011, p.419-492

2011

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Lactone synthesis via biotransformations of γ-hydroxyamides

Tetrahedron: asymmetry, 2004-12, Vol.15 (24), p.3819-3821

2004

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I. Efforts toward the total synthesis of (-)-crambidine. II. Reactions of Azy(3-Me)-containing peptides with thiols and selenols

Ide, Nathan D

2006

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Nitrosamine Reactivity: A Survey of Reactions and Purge Processes

Annulation of Thioimidates and Vinyl Carbodiimides to Prepare 2-Aminopyrimidines, Competent Nucleophiles for Intramolecular Alkyne Hydroamination. Synthesis of (−)-Crambidine

Aziridine-2-carboxylic Acid-Containing Peptides: Application to Solution- and Solid-Phase Convergent Site-Selective Peptide Modification

Synthesis of ABBV-168, a 2′-Bromouridine for the Treatment of Hepatitis C

Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated SNAr Coupling

Risk Assessment of the Leachables’ Profile for Small-Molecule Pharmaceutical Drug Substances

New Semi-Automated Computer-Based System for Assessing the Purge of Mutagenic Impurities

A consortium-driven framework to guide the implementation of ICH M7 Option 4 control strategies

Palbociclib Commercial Manufacturing Process Development. Part II: Regioselective Heck Coupling with Polymorph Control for Processability

Palbociclib Commercial Manufacturing Process Development. Part III. Deprotection Followed by Crystallization for API Particle Property Control

Development of a Practical and Convergent Process for the Preparation of Sulopenem

Synthesis of Filibuvir. Part III. Development of a Process for the Reductive Coupling of an Aldehyde and a β‑Keto-lactone

Development of a Practical and Efficient Synthesis of Chloromethyl 2-Ethoxy-2-methylpropanoate

Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated S N Ar Coupling

Selected Free Radical Reactions

Statistical tools to aid in the assessment of critical process parameters

Reductions

Selected Catalytic Reactions

Palbociclib (Ibrance): The First‐in‐Class CDK4/6 Inhibitor for Breast Cancer

Selected Free Radical Reactions

Conjugation of Selenols with Aziridine-2-Carboxylic Acid-Containing Peptides

Selected Metal-Mediated Cross-Coupling Reactions

Reductions

Lactone synthesis via biotransformations of γ-hydroxyamides

I. Efforts toward the total synthesis of (-)-crambidine. II. Reactions of Azy(3-Me)-containing peptides with thiols and selenols

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