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Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases

Biochimica et biophysica acta. General subjects, 2019-09, Vol.1863 (9), p.1398-1409

2019

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Cell volume regulation in cancer cell migration driven by osmotic water flow

Cancer science, 2019-08, Vol.110 (8), p.2337-2347

2019

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Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling

Biochimica et biophysica acta, 2008-11, Vol.1780 (11), p.1325-1336

2008

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The Lysosome Rupture-activated TAK1-JNK Pathway Regulates NLRP3 Inflammasome Activation

The Journal of biological chemistry, 2014-11, Vol.289 (47), p.32926-32936

2014

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Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose)

Nature communications, 2021-03, Vol.12 (1), p.1353-1353, Article 1353

2021

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From receptors to stress-activated MAP kinases

Oncogene, 1999-11, Vol.18 (45), p.6087-6093

Ichijo, H

1999

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Mitogen-activated protein kinases as key players in osmotic stress signaling

Biochimica et biophysica acta, 2016-09, Vol.1860 (9), p.2037-2052

2016

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The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction

eLife, 2016-08, Vol.5

2016

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Molecular functions of ASK family in diseases caused by stress-induced inflammation and apoptosis

Journal of biochemistry (Tokyo), 2021-04, Vol.169 (4), p.395-407

2021

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FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells

Current biology, 2021-03, Vol.31 (5), p.1048-1057.e5

2021

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The mitochondrial Ca2+ uptake regulator, MICU1, is involved in cold stress‐induced ferroptosis

EMBO reports, 2021-05, Vol.22 (5), p.e51532-n/a

2021

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The CCR4-NOT deadenylase complex safeguards thymic positive selection by down-regulating aberrant pro-apoptotic gene expression

Nature communications, 2020-12, Vol.11 (1), p.6169-12, Article 6169

2020

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In vivo gene manipulation reveals the impact of stress‐responsive MAPK pathways on tumor progression

Cancer science, 2015-07, Vol.106 (7), p.785-796

2015

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Stress-Responsive Protein Kinases in Redox-Regulated Apoptosis Signaling

Antioxidants & redox signaling, 2005-03, Vol.7 (3-4), p.472-481

2005

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Oxidative Stress-Induced Diseases via the ASK1 Signaling Pathway

International Journal of Cell Biology, 2012, Vol.2012 (2012), p.1-5

2012

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Apoptosis signal-regulating kinase 1 as a therapeutic target

Expert opinion on therapeutic targets, 2014-06, Vol.18 (6), p.651-664

2014

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Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase phosphorylation

The Journal of biological chemistry, 2023-02, Vol.299 (2), p.102837-102837, Article 102837

2023

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Apoptosis Signal-Regulating Kinase 1 in Stress and Immune Response

Annual review of pharmacology and toxicology, 2008-01, Vol.48 (1), p.199-225

2008

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ASK1 signalling regulates brown and beige adipocyte function

Nature communications, 2016-04, Vol.7 (1), p.11158-11158, Article 11158

2016

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ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1

Genes & development, 2008-06, Vol.22 (11), p.1451-1464

2008

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Cryo-EM structures of the human volume-regulated anion channel LRRC8

Nature structural & molecular biology, 2018-09, Vol.25 (9), p.797-804

2018

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Mitochondrial proteolysis: its emerging roles in stress responses

Biochimica et biophysica acta, 2015-02, Vol.1850 (2), p.274-280

2015

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A PP6-ASK3 Module Coordinates the Bidirectional Cell Volume Regulation under Osmotic Stress

Cell reports (Cambridge), 2018-03, Vol.22 (11), p.2809-2817

2018

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A Novel Lens for Cell Volume Regulation: Liquid-Liquid Phase Separation

Cellular physiology and biochemistry, 2021-04, Vol.55 (S1), p.135-160

2021

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Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases

Cell volume regulation in cancer cell migration driven by osmotic water flow

Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling

The Lysosome Rupture-activated TAK1-JNK Pathway Regulates NLRP3 Inflammasome Activation

Cells recognize osmotic stress through liquid-liquid phase separation lubricated with poly(ADP-ribose)

From receptors to stress-activated MAP kinases

Mitogen-activated protein kinases as key players in osmotic stress signaling

The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction

Molecular functions of ASK family in diseases caused by stress-induced inflammation and apoptosis

FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells

The mitochondrial Ca2+ uptake regulator, MICU1, is involved in cold stress‐induced ferroptosis

The CCR4-NOT deadenylase complex safeguards thymic positive selection by down-regulating aberrant pro-apoptotic gene expression

In vivo gene manipulation reveals the impact of stress‐responsive MAPK pathways on tumor progression

Stress-Responsive Protein Kinases in Redox-Regulated Apoptosis Signaling

Oxidative Stress-Induced Diseases via the ASK1 Signaling Pathway

Apoptosis signal-regulating kinase 1 as a therapeutic target

Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase phosphorylation

Apoptosis Signal-Regulating Kinase 1 in Stress and Immune Response

ASK1 signalling regulates brown and beige adipocyte function

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1

Cryo-EM structures of the human volume-regulated anion channel LRRC8

Mitochondrial proteolysis: its emerging roles in stress responses

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis

A PP6-ASK3 Module Coordinates the Bidirectional Cell Volume Regulation under Osmotic Stress

A Novel Lens for Cell Volume Regulation: Liquid-Liquid Phase Separation

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