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Discovery and optimization of 2,3-diaryl-1,3-thiazolidin-4-one-based derivatives as potent and selective cytotoxic agents with anti-inflammatory activity

European journal of medicinal chemistry, 2023-11, Vol.259, p.115712-115712, Article 115712

2023

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Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential cytotoxicity and CDK inhibitory activities

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.15-33

2021

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Discovery of new pyrimidopyrrolizine/indolizine-based derivatives as P-glycoprotein inhibitors: Design, synthesis, cytotoxicity, and MDR reversal activities

European journal of medicinal chemistry, 2021-06, Vol.218, p.113403, Article 113403

2021

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Synthesis of novel pyrazole and dihydropyrazoles derivatives as potential anti-inflammatory and analgesic agents

Archives of Pharmacal Research, 2012, 35(5), , pp.807-821

2012

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Covalent small-molecule inhibitors of SARS-CoV-2 Mpro: Insights into their design, classification, biological activity, and binding interactions

European journal of medicinal chemistry, 2024-11, Vol.277, p.116704, Article 116704

2024

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Novel substituted and fused pyrrolizine derivatives: Synthesis, anti-inflammatory and ulcerogenecity studies

European journal of medicinal chemistry, 2010-02, Vol.45 (2), p.482-491

2010

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Synthesis, anti-inflammatory and ulcerogenicity studies of some substituted pyrimido[1,6-a]azepine derivatives

European journal of medicinal chemistry, 2010-07, Vol.45 (7), p.3147-3154

2010

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Design, synthesis and molecular docking of 1,2,4-triazole schiff base hybrids as tubulin, EGFR inhibitors and apoptosis-inducers

Journal of molecular structure, 2023-08, Vol.1286, p.135621, Article 135621

2023

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Resveratrol, a natural phytoalexin: A therapeutic promise for metabolic disorders in streptozotocin-nicotinamide induced type 2 diabetic rats

The Egyptian journal of biochemistry & molecular biology : EJB, 2011-06, Vol.29 (1)

2011

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Synthesis and antitumor evaluation of some novel pyrrolizine derivatives

Medicinal chemistry research, 2012-09, Vol.21 (9), p.2349-2362

2012

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Potential anti-inflammatory activity and ulcerogenicity study of some novel pyrimido[4′,5′:4,5]pyrimido[1,6-a]azepine derivatives

Medicinal chemistry research, 2012-03, Vol.21 (3), p.395-405

2012

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Development of a Multi-Target Pharmacophore-Based Virtual Screening Agent Against COVID-19

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences, 2024-05, Vol.2 (1)

2024

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ChemInform Abstract: Synthesis, Antiinflammatory and Ulcerogenicity Studies of Some Substituted Pyrimido[1,6-a]azepine Derivatives

ChemInform, 2010-10, Vol.41 (42), p.no-no

2010

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ChemInform Abstract: Novel Substituted and Fused Pyrrolizine Derivatives: Synthesis, Antiinflammatory and Ulcerogenecity Studies

ChemInform, 2010-06, Vol.41 (23), p.no-no

2010

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Using Delphi method to address factors contributing to aggressive behaviour in mental health settings

Journal of psychiatric and mental health nursing, 2024-03

2024

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Assessment of Knowledge, Attitudes, and Perception of Health Care Workers Regarding COVID-19, A Cross-Sectional Study from Egypt

Journal of community health, 2020-12, Vol.45 (6), p.1242-1251

2020

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Bioethanol production from defatted biomass of Nannochloropsis oculata microalgae grown under mixotrophic conditions

Environmental science and pollution research international, 2022, Vol.29 (2), p.2588-2597

2022

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Biosorption optimization, characterization, immobilization and application of Gelidium amansii biomass for complete Pb2+ removal from aqueous solutions

Scientific reports, 2018-09, Vol.8 (1), p.1-19, Article 13456

2018

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Erlotinib can halt adenine induced nephrotoxicity in mice through modulating ERK1/2, STAT3, p53 and apoptotic pathways

Scientific reports, 2020-07, Vol.10 (1), p.11524-13, Article 11524

2020

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Therapeutic potentials of mesenchymal stem cells in the treatment of inflammatory bowel disease in rats

Journal of biochemical and molecular toxicology, 2024-01, Vol.38 (1), p.e23532-n/a

2024

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Nephroprotective effects of Acacia senegal against aflatoxicosis via targeting inflammatory and apoptotic signaling pathways

Ecotoxicology and environmental safety, 2023-09, Vol.262, p.115194-115194, Article 115194

2023

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Antifibrotic effects of bezafibrate and pioglitazone against thioacetamide-induced liver fibrosis in albino rats

Canadian journal of physiology and pharmacology, 2021-03, Vol.99 (3), p.313-320

2021

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Evaluation of the effect of combined intralesional injection of prostaglandin F2α with narrow band UVB phototherapy in treatment of resistant cases of vitiligo

The Journal of dermatological treatment, 2021-05, Vol.32 (4), p.383-390

2021

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Evidence of a Link between Hepatitis E Virus Exposure and Glomerulonephritis Development

Viruses, 2023-06, Vol.15 (6), p.1379

2023

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Epigallocatechin‐3‐gallate in combination with corticosteroids mitigates heat stress‐induced acute kidney injury through modulating heat shock protein 70 and toll‐like receptor 4‐dependent pathways

Phytotherapy research, 2023-08, Vol.37 (8), p.3559-3571

2023

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Discovery and optimization of 2,3-diaryl-1,3-thiazolidin-4-one-based derivatives as potent and selective cytotoxic agents with anti-inflammatory activity

Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential cytotoxicity and CDK inhibitory activities

Discovery of new pyrimidopyrrolizine/indolizine-based derivatives as P-glycoprotein inhibitors: Design, synthesis, cytotoxicity, and MDR reversal activities

Synthesis of novel pyrazole and dihydropyrazoles derivatives as potential anti-inflammatory and analgesic agents

Covalent small-molecule inhibitors of SARS-CoV-2 Mpro: Insights into their design, classification, biological activity, and binding interactions

Novel substituted and fused pyrrolizine derivatives: Synthesis, anti-inflammatory and ulcerogenecity studies

Synthesis, anti-inflammatory and ulcerogenicity studies of some substituted pyrimido[1,6-a]azepine derivatives

Design, synthesis and molecular docking of 1,2,4-triazole schiff base hybrids as tubulin, EGFR inhibitors and apoptosis-inducers

Resveratrol, a natural phytoalexin: A therapeutic promise for metabolic disorders in streptozotocin-nicotinamide induced type 2 diabetic rats

Synthesis and antitumor evaluation of some novel pyrrolizine derivatives

Potential anti-inflammatory activity and ulcerogenicity study of some novel pyrimido[4′,5′:4,5]pyrimido[1,6-a]azepine derivatives

Development of a Multi-Target Pharmacophore-Based Virtual Screening Agent Against COVID-19

ChemInform Abstract: Synthesis, Antiinflammatory and Ulcerogenicity Studies of Some Substituted Pyrimido[1,6-a]azepine Derivatives

ChemInform Abstract: Novel Substituted and Fused Pyrrolizine Derivatives: Synthesis, Antiinflammatory and Ulcerogenecity Studies

Using Delphi method to address factors contributing to aggressive behaviour in mental health settings

Assessment of Knowledge, Attitudes, and Perception of Health Care Workers Regarding COVID-19, A Cross-Sectional Study from Egypt

Bioethanol production from defatted biomass of Nannochloropsis oculata microalgae grown under mixotrophic conditions

Biosorption optimization, characterization, immobilization and application of Gelidium amansii biomass for complete Pb2+ removal from aqueous solutions

Erlotinib can halt adenine induced nephrotoxicity in mice through modulating ERK1/2, STAT3, p53 and apoptotic pathways

Therapeutic potentials of mesenchymal stem cells in the treatment of inflammatory bowel disease in rats

Nephroprotective effects of Acacia senegal against aflatoxicosis via targeting inflammatory and apoptotic signaling pathways

Antifibrotic effects of bezafibrate and pioglitazone against thioacetamide-induced liver fibrosis in albino rats

Evaluation of the effect of combined intralesional injection of prostaglandin F2α with narrow band UVB phototherapy in treatment of resistant cases of vitiligo

Evidence of a Link between Hepatitis E Virus Exposure and Glomerulonephritis Development

Epigallocatechin‐3‐gallate in combination with corticosteroids mitigates heat stress‐induced acute kidney injury through modulating heat shock protein 70 and toll‐like receptor 4‐dependent pathways

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