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Novel 3-(pyrazol-4-yl)-2-(1H-indole-3-carbonyl)acrylonitrile derivatives induce intrinsic and extrinsic apoptotic death mediated P53 in HCT116 colon carcinoma

Scientific reports, 2023-12, Vol.13 (1), p.22486-22486, Article 22486

2023

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Impact of trifluoromethyl and sulfonyl groups on the biological activity of novel aryl-urea derivatives: synthesis, in-vitro, in-silico and SAR studies

Scientific reports, 2023-10, Vol.13 (1), p.17560-17560, Article 17560

2023

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Molecular Studies on Novel Antitumor Bis 1,4-Dihydropyridine Derivatives Against Lung Carcinoma and their Limited Side Effects on Normal Melanocytes

Anti-cancer agents in medicinal chemistry, 2018-01, Vol.18 (15), p.2156-2168

2018

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Synthesis, Cytotoxicity and Molecular Docking Simulation of Novel bis-1,4-Dihydropyridines Linked to Aliphatic or Arene Core via Amide or Ester-Amide Linkages

Mini reviews in medicinal chemistry, 2020-01, Vol.20 (9), p.801-816

2020

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Novel Scaffolds Based on Bis-thiazole Connected to Quinoxaline or Thienothiophene through 2-Phenoxy- N -arylacetamide Groups as New Hybrid Molecules: Synthesis, Antibacterial Activity, and Molecular Docking Investigations

ACS omega, 2023-11, Vol.8 (46), p.44312-44327

2023

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Design, synthesis, in vitro anticancer, molecular docking and SAR studies of new series of pyrrolo[2,3-d]pyrimidine derivatives

BMC chemistry, 2023-08, Vol.17 (1), p.106-106, Article 106

2023

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Biological Activities and Docking Studies on Novel Bis 1,4-DHPS Linked to Arene Core via Ether or Ester Linkage

Letters in drug design & discovery, 2018-01, Vol.15 (10), p.1036-1045

2018

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Synthesis, cytotoxicity, anti-inflammatory, anti-metastatic and anti-oxidant activities of novel chalcones incorporating 2-phenoxy-N-arylacetamide and thiophene moieties: induction of apoptosis in MCF7 and HEP2 cells

Naunyn-Schmiedeberg's archives of pharmacology, 2024-07

2024

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Bee venom and its active component Melittin synergistically potentiate the anticancer effect of Sorafenib against HepG2 cells

Bioorganic chemistry, 2021-11, Vol.116, p.105329, Article 105329

2021

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Novel [l,2,4]triazolo[3,4-a]isoquinoline chalcones as new chemotherapeutic agents: Block IAP tyrosine kinase domain and induce both intrinsic and extrinsic pathways of apoptosis

Investigational new drugs, 2021-02, Vol.39 (1), p.98-110

2021

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Theoretical and molecular mechanistic investigations of novel (3-(furan-2-yl)pyrazol-4-yl) chalcones against lung carcinoma cell line (A549)

Naunyn-Schmiedeberg's archives of pharmacology, 2023-04, Vol.396 (4), p.719-736

2023

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In silico and in vitro studies of novel cyanoacrylamides incorporating pyrazole moiety against breast and prostate carcinomas

Medicinal chemistry research, 2023-06, Vol.32 (6), p.1190-1203

2023

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Cytotoxic Activity, Apoptosis Induction and Cell Cycle Arrest in Human Breast Cancer (MCF7) Cells by a Novel Fluorinated Tetrahydro-[1,2,4]Triazolo[3,4-a]Isoquinolin Chalcones

Polycyclic aromatic compounds, 2023-01, Vol.43 (1), p.268-287

2023

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Computational studies and sever apoptotic bioactivity of new heterocyclic cyanoacrylamide based p-fluorophenyl and p-phenolic compounds against liver carcinoma (Hepg2)

Bioorganic chemistry, 2021-09, Vol.114, p.105147-105147, Article 105147

2021

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Synthesis, molecular docking simulation, and antimicrobial activities of novel bis-heterocycles linked to piperazine and vanillin units as novel hybrid molecules via Hantzsch, Biginelli, and Michael’s reactions

Results in Chemistry, 2024-08, Vol.10, p.101684, Article 101684

2024

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Productivity and Quality Variations in Sugar Beet Induced by Soil Application of K-Humate and Foliar Application of Biostimulants Under Salinity Condition

Journal of soil science and plant nutrition, 2023-09, Vol.23 (3), p.3872-3887

2023

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Novel diphenyl ether-heterocycles hybrids: Synthesis via Hantzsch and Biginelli reactions, molecular docking simulation, and antimicrobial activities

Journal of molecular structure, 2024-01, Vol.1296, p.136857, Article 136857

2024

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Synthesis and antibacterial activities of novel hybrid molecules based on benzothiazole, benzimidazole, benzoxazole, and pyrimidine derivatives, each connected to N-arylacetamide and benzoate groups

Journal of molecular structure, 2024-07, Vol.1307, p.137965, Article 137965

2024

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Synthesis, molecular docking, and antimicrobial activity of novel scaffolds based on bis(thiazole) linked to 2-phenoxy-N-arylacetamide as new hybrid molecules

Journal of molecular structure, 2024-04, Vol.1302, p.137506, Article 137506

2024

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Cytotoxic Effect of New ( E )‐2‐Cyano‐ N ‐(tetrahydrobenzo[ b ]thiophen‐2‐yl)acrylamide Derivatives: Down‐Regulation of RBL2 and STAT2 and Triggering of DNA Damage in Breast Carcinoma

ChemistrySelect (Weinheim), 2023-09, Vol.8 (33)

2023

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Integrating Grid Computing Technology into Multimedia Application

International journal of computer trends and technology, 2015-05, Vol.23 (3), p.103-107

2015

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Use of ionizing radiation technology (Co60) for treating crude water

Marsh Bulletin., 2022, Vol.17 (1), p.1-7

2022

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Forecasting Stock Market Returns Via Monte Carlo Simulation: The Case of Amman Stock Exchange

Jordan Journal of Business Administration, 2015, Vol.11 (3), p.745-756

2015

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Experiences of Abused Muslim Women With the Australian Criminal Justice System

Journal of interpersonal violence, 2022-02, Vol.37 (3-4), p.NP2360-NP2386

Ibrahim, Nada

2022

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Drone Deep Reinforcement Learning: A Review

Electronics (Basel), 2021-05, Vol.10 (9), p.999

2021

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Novel 3-(pyrazol-4-yl)-2-(1H-indole-3-carbonyl)acrylonitrile derivatives induce intrinsic and extrinsic apoptotic death mediated P53 in HCT116 colon carcinoma

Impact of trifluoromethyl and sulfonyl groups on the biological activity of novel aryl-urea derivatives: synthesis, in-vitro, in-silico and SAR studies

Molecular Studies on Novel Antitumor Bis 1,4-Dihydropyridine Derivatives Against Lung Carcinoma and their Limited Side Effects on Normal Melanocytes

Synthesis, Cytotoxicity and Molecular Docking Simulation of Novel bis-1,4-Dihydropyridines Linked to Aliphatic or Arene Core via Amide or Ester-Amide Linkages

Novel Scaffolds Based on Bis-thiazole Connected to Quinoxaline or Thienothiophene through 2-Phenoxy- N -arylacetamide Groups as New Hybrid Molecules: Synthesis, Antibacterial Activity, and Molecular Docking Investigations

Design, synthesis, in vitro anticancer, molecular docking and SAR studies of new series of pyrrolo[2,3-d]pyrimidine derivatives

Biological Activities and Docking Studies on Novel Bis 1,4-DHPS Linked to Arene Core via Ether or Ester Linkage

Synthesis, cytotoxicity, anti-inflammatory, anti-metastatic and anti-oxidant activities of novel chalcones incorporating 2-phenoxy-N-arylacetamide and thiophene moieties: induction of apoptosis in MCF7 and HEP2 cells

Bee venom and its active component Melittin synergistically potentiate the anticancer effect of Sorafenib against HepG2 cells

Novel [l,2,4]triazolo[3,4-a]isoquinoline chalcones as new chemotherapeutic agents: Block IAP tyrosine kinase domain and induce both intrinsic and extrinsic pathways of apoptosis

Theoretical and molecular mechanistic investigations of novel (3-(furan-2-yl)pyrazol-4-yl) chalcones against lung carcinoma cell line (A549)

In silico and in vitro studies of novel cyanoacrylamides incorporating pyrazole moiety against breast and prostate carcinomas

Cytotoxic Activity, Apoptosis Induction and Cell Cycle Arrest in Human Breast Cancer (MCF7) Cells by a Novel Fluorinated Tetrahydro-[1,2,4]Triazolo[3,4-a]Isoquinolin Chalcones

Computational studies and sever apoptotic bioactivity of new heterocyclic cyanoacrylamide based p-fluorophenyl and p-phenolic compounds against liver carcinoma (Hepg2)

Synthesis, molecular docking simulation, and antimicrobial activities of novel bis-heterocycles linked to piperazine and vanillin units as novel hybrid molecules via Hantzsch, Biginelli, and Michael’s reactions

Productivity and Quality Variations in Sugar Beet Induced by Soil Application of K-Humate and Foliar Application of Biostimulants Under Salinity Condition

Novel diphenyl ether-heterocycles hybrids: Synthesis via Hantzsch and Biginelli reactions, molecular docking simulation, and antimicrobial activities

Synthesis and antibacterial activities of novel hybrid molecules based on benzothiazole, benzimidazole, benzoxazole, and pyrimidine derivatives, each connected to N-arylacetamide and benzoate groups

Synthesis, molecular docking, and antimicrobial activity of novel scaffolds based on bis(thiazole) linked to 2-phenoxy-N-arylacetamide as new hybrid molecules

Cytotoxic Effect of New ( E )‐2‐Cyano‐ N ‐(tetrahydrobenzo[ b ]thiophen‐2‐yl)acrylamide Derivatives: Down‐Regulation of RBL2 and STAT2 and Triggering of DNA Damage in Breast Carcinoma

Integrating Grid Computing Technology into Multimedia Application

Use of ionizing radiation technology (Co60) for treating crude water

Forecasting Stock Market Returns Via Monte Carlo Simulation: The Case of Amman Stock Exchange

Experiences of Abused Muslim Women With the Australian Criminal Justice System

Drone Deep Reinforcement Learning: A Review

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