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Mechanisms of DNA-reactive and epigenetic chemical carcinogens: applications to carcinogenicity testing and risk assessment

Toxicology research (Cambridge), 2019-03, Vol.8 (2), p.123-145

2019

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Nitric oxide-donating aspirin prevents pancreatic cancer in a hamster tumor model

Cancer research (Chicago, Ill.), 2006-04, Vol.66 (8), p.4503-4511

2006

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Alteration of Liver Cell Function and Proliferation: Differentiation Between Adaptation and Toxicity

Toxicologic pathology, 2002-01, Vol.30 (1), p.41-53

2002

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Assessment of DNA Binding and Oxidative DNA Damage by Acrylonitrile in Two Rat Target Tissues of Carcinogenicity: Implications for the Mechanism of Action

Chemical research in toxicology, 2017-07, Vol.30 (7), p.1470-1480

2017

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Evaluation of potential human carcinogenicity of the synthetic monomer ethyl acrylate

Regulatory toxicology and pharmacology, 2009-02, Vol.53 (1), p.6-15

2009

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In ovo testing of flavor and fragrance materials in Turkey Egg Genotoxicity Assay (TEGA), comparison of results to in vitro and in vivo data

Food and chemical toxicology, 2018-05, Vol.115, p.228-243

2018

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Expression of Genes Encoding for Xenobiotic Metabolism After Exposure to Dialkylnitrosamines in the Chicken Egg Genotoxicity Alternative Model

Toxicological sciences, 2018-11, Vol.166 (1), p.82-96

2018

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Chicken fetal liver DNA damage and adduct formation by activation-dependent DNA-reactive carcinogens and related compounds of several structural classes

Toxicological sciences, 2014-09, Vol.141 (1), p.18-28

2014

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Inhibition by dietary hydroquinone of acetylaminofluorene induction of initiation of rat liver carcinogenesis

Food and chemical toxicology, 2007-09, Vol.45 (9), p.1620-1625

2007

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Methyleugenol hepatocellular cancer initiating effects in rat liver

Food and chemical toxicology, 2013-03, Vol.53, p.187-196

2013

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Sex differences in DNA damage produced by the carcinogen 2-acetylaminofluorene in cultured human hepatocytes compared to rat liver and cultured rat hepatocytes

Archives of toxicology, 2016-02, Vol.90 (2), p.427-432

2016

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GRAS determination scientific procedures and possible alternatives

Regulatory toxicology and pharmacology, 2016-08, Vol.79, p.S105-S111

2016

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Thresholds for the Effects of 2-Acetylaminofluorene in Rat Liver

Toxicologic pathology, 2004-02, Vol.32 (2_suppl), p.85-91

2004

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Mechanistic Basis for Nonlinearities and Thresholds in Rat Liver Carcinogenesis by the DNA-Reactive Carcinogens 2-Acetylaminofluorene and Diethylnitrosamine

Toxicologic pathology, 2000-05, Vol.28 (3), p.388-395

2000

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The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat

Food and chemical toxicology, 2014-12, Vol.74, p.28-34

2014

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Consensus Diagnoses and Mode of Action for the Formation of Gastric Tumors in Rats Treated with the Chloroacetanilide Herbicides Alachlor and Butachlor

Toxicologic pathology, 2014-02, Vol.42 (2), p.386-402

2014

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Thresholds for DNA-Reactive (Genotoxic) Organic Carcinogens

Journal of Toxicologic Pathology, 2005, Vol.18(2), pp.69-77

2005

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A no observed adverse effect level for DNA adduct formation in rat liver with prolonged dosing of the hepatocarcinogen 2-acetylaminofluorene

Toxicology research (Cambridge), 2015-01, Vol.4 (2), p.233-24

2015

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Dose-dependent induction of preneoplastic lesions by the tobacco-specific nitrosamine carcinogen NNK in the in ovo carcinogenicity assessment (IOCA) assay

Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, 2014-01, Vol.66 (1), p.35-40

2014

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Production of liver preneoplasia and gallbladder agenesis in turkey fetuses administered diethylnitrosamine

Archives of toxicology, 2011-06, Vol.85 (6), p.681-687

2011

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Major difference in the hepatocarcinogenicity and DNA adduct forming ability between toremifene and tamoxifen in female Crl:CD(BR) rats

Cancer research (Chicago, Ill.), 1993-10, Vol.53 (19), p.4534-4541

1993

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Nasal Cytotoxic and Carcinogenic Activities of Systemically Distributed Organic Chemicals

Toxicologic pathology, 2006-01, Vol.34 (7), p.827-852

2006

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Inhibition of lung carcinogenesis by black tea in fischer rats treated with a tobacco-specific carcinogen : Caffeine as an important constituent

Cancer research (Chicago, Ill.), 1998-09, Vol.58 (18), p.4096-4101

1998

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Acrylonitrile induction of rodent neoplasia: Potential mechanism of action and relevance to humans

Toxicology Research and Application, 2022-06, Vol.6

2022

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Inhibition by acetaminophen of neoplastic initiation elicited in rat liver by the DNA-reactive hepatocarcinogen N-acetyl-2-aminofluorene

European journal of cancer prevention, 2007-12, Vol.16 (6), p.528-534

2007

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Mechanisms of DNA-reactive and epigenetic chemical carcinogens: applications to carcinogenicity testing and risk assessment

Nitric oxide-donating aspirin prevents pancreatic cancer in a hamster tumor model

Alteration of Liver Cell Function and Proliferation: Differentiation Between Adaptation and Toxicity

Assessment of DNA Binding and Oxidative DNA Damage by Acrylonitrile in Two Rat Target Tissues of Carcinogenicity: Implications for the Mechanism of Action

Evaluation of potential human carcinogenicity of the synthetic monomer ethyl acrylate

In ovo testing of flavor and fragrance materials in Turkey Egg Genotoxicity Assay (TEGA), comparison of results to in vitro and in vivo data

Expression of Genes Encoding for Xenobiotic Metabolism After Exposure to Dialkylnitrosamines in the Chicken Egg Genotoxicity Alternative Model

Chicken fetal liver DNA damage and adduct formation by activation-dependent DNA-reactive carcinogens and related compounds of several structural classes

Inhibition by dietary hydroquinone of acetylaminofluorene induction of initiation of rat liver carcinogenesis

Methyleugenol hepatocellular cancer initiating effects in rat liver

Sex differences in DNA damage produced by the carcinogen 2-acetylaminofluorene in cultured human hepatocytes compared to rat liver and cultured rat hepatocytes

GRAS determination scientific procedures and possible alternatives

Thresholds for the Effects of 2-Acetylaminofluorene in Rat Liver

Mechanistic Basis for Nonlinearities and Thresholds in Rat Liver Carcinogenesis by the DNA-Reactive Carcinogens 2-Acetylaminofluorene and Diethylnitrosamine

The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat

Consensus Diagnoses and Mode of Action for the Formation of Gastric Tumors in Rats Treated with the Chloroacetanilide Herbicides Alachlor and Butachlor

Thresholds for DNA-Reactive (Genotoxic) Organic Carcinogens

A no observed adverse effect level for DNA adduct formation in rat liver with prolonged dosing of the hepatocarcinogen 2-acetylaminofluorene

Dose-dependent induction of preneoplastic lesions by the tobacco-specific nitrosamine carcinogen NNK in the in ovo carcinogenicity assessment (IOCA) assay

Production of liver preneoplasia and gallbladder agenesis in turkey fetuses administered diethylnitrosamine

Major difference in the hepatocarcinogenicity and DNA adduct forming ability between toremifene and tamoxifen in female Crl:CD(BR) rats

Nasal Cytotoxic and Carcinogenic Activities of Systemically Distributed Organic Chemicals

Inhibition of lung carcinogenesis by black tea in fischer rats treated with a tobacco-specific carcinogen : Caffeine as an important constituent

Acrylonitrile induction of rodent neoplasia: Potential mechanism of action and relevance to humans

Inhibition by acetaminophen of neoplastic initiation elicited in rat liver by the DNA-reactive hepatocarcinogen N-acetyl-2-aminofluorene

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