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Methylation of multiple genes as molecular markers for diagnosis of a small, well‐differentiated hepatocellular carcinoma

International journal of cancer, 2009-07, Vol.125 (2), p.388-397

2009

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Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection

The Lancet (British edition), 2003-03, Vol.361 (9361), p.923-929

2003

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X-Ray Irradiation Induces Thymidine Phosphorylase and Enhances the Efficacy of Capecitabine (Xeloda) in Human Cancer Xenografts

Clinical cancer research, 1999-10, Vol.5 (10), p.2948-2953

1999

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Elevated Levels of Circulating Cell-free DNA in the Blood of Patients with Hepatitis C Virus-associated Hepatocellular Carcinoma

Anticancer research, 2006-11, Vol.26 (6C), p.4713-4719

2006

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Efficient detection of hepatocellular carcinoma by a hybrid blood test of epigenetic and classical protein markers

Clinica chimica acta, 2011-01, Vol.412 (1), p.152-158

2011

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Methylated cyclin D2 gene circulating in the blood as a prognosis predictor of hepatocellular carcinoma

Clinica chimica acta, 2010-04, Vol.411 (7), p.516-520

2010

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Induction of thymidine phosphorylase expression and enhancement of efficacy of capecitabine or 5′‐deoxy‐5‐fluorouridine by cyclophosphamide in mammary tumor models

International journal of cancer, 1999-09, Vol.83 (1), p.127-134

1999

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The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, Capecitabine

Bioorganic & medicinal chemistry, 2000-07, Vol.8 (7), p.1697-1706

2000

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Self-organizing-map-based molecular signature representing the development of hepatocellular carcinoma

FEBS letters, 2005-02, Vol.579 (5), p.1089-1100

2005

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Expression of platelet‐derived endothelial cell growth factor/thymidine phosphorylase in human breast cancer

International journal of cancer, 1995-04, Vol.64 (2), p.79-82

1995

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Capecitabine: preclinical pharmacology studies

Investigational new drugs, 2000-11, Vol.18 (4), p.343-354

Ishitsuka, H

2000

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Preparation of Anti-human Thymidine Phosphorylase Monoclonal antibodies Useful for Detecting the Enzyme Levels in Tumor Tissues

Biological and Pharmaceutical Bulletin, 1996/11/15, Vol.19(11), pp.1407-1411

1996

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Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5'-deoxy-5-fluorouridine

Cancer chemotherapy and pharmacology, 1993, Vol.32 (5), p.333-338

1993

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Establishment and characterization of cachexia‐inducing and ‐non‐inducing clones of murine colon 26 carcinoma

International journal of cancer, 1995-05, Vol.61 (4), p.522-528

1995

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Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts

Cancer research (Chicago, Ill.), 1998-02, Vol.58 (4), p.685-690

1998

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Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889

International journal of cancer, 2003-09, Vol.106 (5), p.799-805

2003

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Induction of thymidine phosphorylase activity and enhancement of capecitabine efficacy by taxol/taxotere in human cancer xenografts

Clinical cancer research, 1998-04, Vol.4 (4), p.1013-1019

1998

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Identification of novel aberrant methylation of BASP1 and SRD5A2 for early diagnosis of hepatocellular carcinoma by genome-wide search

International journal of oncology, 2008-11, Vol.33 (5), p.949-958

2008

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Comparative studies on the antirhinovirus activity and the mode of action of the rhinovirus capsid binding agents, chalcone amides

Antiviral research, 1990-02, Vol.13 (2), p.61-74

1990

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Selective inhibition of spontaneous pulmonary metastasis of lewis lung carcinoma by 5′‐deoxy‐5‐fluorouridine

International journal of cancer, 1995-05, Vol.61 (4), p.516-521

1995

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Rapid and quantitative detection of CpG-methylation status using TaqMan PCR combined with methyl-binding-domain polypeptide

Clinical biochemistry, 2009-07, Vol.42 (10), p.1113-1122

2009

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A physiologically based pharmacokinetic analysis of capecitabine, a triple prodrug of 5-FU, in humans : The mechanism for tumor-selective accumulation of 5-FU

Pharmaceutical research, 2001-08, Vol.18 (8), p.1190-1202

2001

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Capecitabine : preclinical pharmacology studies: The Oral Fluorinated Pyrimidines

Investigational new drugs, 2000, Vol.18 (4), p.343-354

ISHITSUKA, Hideo

2000

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Antitumor Activities of A Novel Fluoropyrimidine, N4-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine (Capecitabine)

Biological and Pharmaceutical Bulletin, 1998/07/15, Vol.21(7), pp.713-717

1998

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Relation between serum levels of cell-free DNA and inflammation status in hepatitis C virus-related hepatocellular carcinoma

Oncology reports, 2008-10, Vol.20 (4), p.761-765

2008

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Methylation of multiple genes as molecular markers for diagnosis of a small, well‐differentiated hepatocellular carcinoma

Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection

X-Ray Irradiation Induces Thymidine Phosphorylase and Enhances the Efficacy of Capecitabine (Xeloda) in Human Cancer Xenografts

Elevated Levels of Circulating Cell-free DNA in the Blood of Patients with Hepatitis C Virus-associated Hepatocellular Carcinoma

Efficient detection of hepatocellular carcinoma by a hybrid blood test of epigenetic and classical protein markers

Methylated cyclin D2 gene circulating in the blood as a prognosis predictor of hepatocellular carcinoma

Induction of thymidine phosphorylase expression and enhancement of efficacy of capecitabine or 5′‐deoxy‐5‐fluorouridine by cyclophosphamide in mammary tumor models

The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, Capecitabine

Self-organizing-map-based molecular signature representing the development of hepatocellular carcinoma

Expression of platelet‐derived endothelial cell growth factor/thymidine phosphorylase in human breast cancer

Capecitabine: preclinical pharmacology studies

Preparation of Anti-human Thymidine Phosphorylase Monoclonal antibodies Useful for Detecting the Enzyme Levels in Tumor Tissues

Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5'-deoxy-5-fluorouridine

Establishment and characterization of cachexia‐inducing and ‐non‐inducing clones of murine colon 26 carcinoma

Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts

Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889

Induction of thymidine phosphorylase activity and enhancement of capecitabine efficacy by taxol/taxotere in human cancer xenografts

Identification of novel aberrant methylation of BASP1 and SRD5A2 for early diagnosis of hepatocellular carcinoma by genome-wide search

Comparative studies on the antirhinovirus activity and the mode of action of the rhinovirus capsid binding agents, chalcone amides

Selective inhibition of spontaneous pulmonary metastasis of lewis lung carcinoma by 5′‐deoxy‐5‐fluorouridine

Rapid and quantitative detection of CpG-methylation status using TaqMan PCR combined with methyl-binding-domain polypeptide

A physiologically based pharmacokinetic analysis of capecitabine, a triple prodrug of 5-FU, in humans : The mechanism for tumor-selective accumulation of 5-FU

Capecitabine : preclinical pharmacology studies: The Oral Fluorinated Pyrimidines

Antitumor Activities of A Novel Fluoropyrimidine, N4-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine (Capecitabine)

Relation between serum levels of cell-free DNA and inflammation status in hepatitis C virus-related hepatocellular carcinoma

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