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Pharmacokinetics of an intracerebroventricularly administered antibody in rats

mAbs, 2017-10, Vol.9 (7), p.1210-1215

2017

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Injectable Hydrogel for Sustained Protein Release by Salt-Induced Association of Hyaluronic Acid Nanogel

Macromolecular bioscience, 2012-04, Vol.12 (4), p.475-483

2012

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Application of human FcRn transgenic mice as a pharmacokinetic screening tool of monoclonal antibody

Xenobiotica, 2014-12, Vol.44 (12), p.1127-1134

2014

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A versatile method for protein-based antigen bioanalysis in non-clinical pharmacokinetics studies of a human monoclonal antibody drug by an immunoaffinity liquid chromatography–tandem mass spectrometry

Journal of Chromatography A, 2014-03, Vol.1334, p.64-71

2014

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Estimating efflux transporter-mediated disposition using transporter gene knockout rats

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S21-S21

2019

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Quantitative prediction of CYP3A4 Induction using simple relative factor approach

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S42-S43

2019

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Intracellular Dynamics and Fate of a Humanized Anti-Interleukin-6 Receptor Monoclonal Antibody, Tocilizumab

Molecular pharmacology, 2015-10, Vol.88 (4), p.660-675

2015

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Tofogliflozin Salt Cocrystals with Sodium Acetate and Potassium Acetate

Chemical and Pharmaceutical Bulletin, 2018/11/01, Vol.66(11), pp.1035-1040

2018

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Evaluation of the appropriate time range for estimating the apparent permeability coefficient (Papp) in a transcellular transport study

International journal of pharmaceutics, 2015-11, Vol.495 (2), p.963-971

2015

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Characterization of phase I and phase II metabolism of UR-1102, a novel agent for the treatment of gout

Drug metabolism and pharmacokinetics, 2018-01, Vol.33 (1), p.S29-S29

2018

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A trial proteomics fingerprint analysis of HepaRG cells by FD-LC-MS/MS

Analyst (London), 2015-01, Vol.140 (1), p.71-73

2015

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Risk of CYP2C9 induction analyzed by a relative factor approach with human hepatocytes

Drug metabolism and pharmacokinetics, 2019-10, Vol.34 (5), p.325-333

2019

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A new approach to predicting human hepatic clearance of CYP3A4 substrates using monkey pharmacokinetic data

Xenobiotica, 2013-05, Vol.43 (5), p.468-478

2013

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Bridging from Preclinical to Clinical Studies for Tyrosine Kinase Inhibitors Based on Pharmacokinetics/Pharmacodynamics and Toxicokinetics/Toxicodynamics

DRUG METABOLISM AND PHARMACOKINETICS, 2011-01, Vol.26 (6), p.612-620

2011

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Pharmacokinetic and pharmacodynamic modeling of the effect of an sodium-glucose cotransporter inhibitor, phlorizin, on renal glucose transport in rats

Drug metabolism and disposition, 2011-10, Vol.39 (10), p.1801-1807

2011

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Assessing the Impact of HER2 Status on the Antitumor Activity of an HSP90 Inhibitor in Human Tumor Xenograft Mice Using Pharmacokinetic–Pharmacodynamic Modeling

DRUG METABOLISM AND PHARMACOKINETICS, 2014, Vol.29 (2), p.185-191

2014

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Prediction of Drug-Drug Interactions based on Time-Dependent Inhibition from High Throughput Screening of Cytochrome P450 3A4 Inhibition

DRUG METABOLISM AND PHARMACOKINETICS, 2009-01, Vol.24 (6), p.500-510

2009

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PK/PD analysis of a novel pH-dependent antigen-binding antibody using a dynamic antibody–antigen binding model

Drug metabolism and pharmacokinetics, 2016-04, Vol.31 (2), p.123-132

2016

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A series of nonsecosteroidal vitamin D receptor agonists for osteoporosis therapy

Bioorganic & medicinal chemistry, 2013-04, Vol.21 (7), p.1823-1833

2013

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Comparison of in vitro metabolic conversion of capecitabine to 5-FU in rats, mice, monkeys and humans - toxicological implications

The Journal of Toxicological Sciences, 2011/08/01, Vol.36(4), pp.411-422

2011

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Comprehensive and temporal analysis of secreted proteins in the medium from IL-6 exposed human hepatocyte

Biomedical chromatography, 2014-06, Vol.28 (6), p.742-750

2014

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Antigen-dependent internalization is related to rapid elimination from plasma of humanized anti-HM1.24 monoclonal antibody

Drug metabolism and disposition, 2010-12, Vol.38 (12), p.2339-2346

2010

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In vitro metabolism of alectinib, a novel highly potent alk inhibitor: Contribution of CYP3A enzymes in microsomes and hepatocytes

Drug metabolism and pharmacokinetics, 2017-01, Vol.32 (1), p.S80-S81

2017

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Simple and sensitive quantification of bioactive peptides in biological matrices using liquid chromatography/selected reaction monitoring mass spectrometry coupled with trichloroacetic acid clean-up

Rapid communications in mass spectrometry, 2007-12, Vol.21 (24), p.4033-4038

2007

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Pharmacokinetics of an intracerebroventricularly administered antibody in rats

Injectable Hydrogel for Sustained Protein Release by Salt-Induced Association of Hyaluronic Acid Nanogel

Application of human FcRn transgenic mice as a pharmacokinetic screening tool of monoclonal antibody

A versatile method for protein-based antigen bioanalysis in non-clinical pharmacokinetics studies of a human monoclonal antibody drug by an immunoaffinity liquid chromatography–tandem mass spectrometry

Estimating efflux transporter-mediated disposition using transporter gene knockout rats

Quantitative prediction of CYP3A4 Induction using simple relative factor approach

Intracellular Dynamics and Fate of a Humanized Anti-Interleukin-6 Receptor Monoclonal Antibody, Tocilizumab

Tofogliflozin Salt Cocrystals with Sodium Acetate and Potassium Acetate

Evaluation of the appropriate time range for estimating the apparent permeability coefficient (Papp) in a transcellular transport study

Characterization of phase I and phase II metabolism of UR-1102, a novel agent for the treatment of gout

A trial proteomics fingerprint analysis of HepaRG cells by FD-LC-MS/MS

Risk of CYP2C9 induction analyzed by a relative factor approach with human hepatocytes

A new approach to predicting human hepatic clearance of CYP3A4 substrates using monkey pharmacokinetic data

Bridging from Preclinical to Clinical Studies for Tyrosine Kinase Inhibitors Based on Pharmacokinetics/Pharmacodynamics and Toxicokinetics/Toxicodynamics

Pharmacokinetic and pharmacodynamic modeling of the effect of an sodium-glucose cotransporter inhibitor, phlorizin, on renal glucose transport in rats

Assessing the Impact of HER2 Status on the Antitumor Activity of an HSP90 Inhibitor in Human Tumor Xenograft Mice Using Pharmacokinetic–Pharmacodynamic Modeling

Prediction of Drug-Drug Interactions based on Time-Dependent Inhibition from High Throughput Screening of Cytochrome P450 3A4 Inhibition

PK/PD analysis of a novel pH-dependent antigen-binding antibody using a dynamic antibody–antigen binding model

A series of nonsecosteroidal vitamin D receptor agonists for osteoporosis therapy

Comparison of in vitro metabolic conversion of capecitabine to 5-FU in rats, mice, monkeys and humans - toxicological implications

Comprehensive and temporal analysis of secreted proteins in the medium from IL-6 exposed human hepatocyte

Antigen-dependent internalization is related to rapid elimination from plasma of humanized anti-HM1.24 monoclonal antibody

In vitro metabolism of alectinib, a novel highly potent alk inhibitor: Contribution of CYP3A enzymes in microsomes and hepatocytes

An anti-glypican 3/CD3 bispecific T cell-redirecting antibody for treatment of solid tumors

Simple and sensitive quantification of bioactive peptides in biological matrices using liquid chromatography/selected reaction monitoring mass spectrometry coupled with trichloroacetic acid clean-up

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