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Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway

Bioorganic & medicinal chemistry, 2011-10, Vol.19 (20), p.6006-6014

2011

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TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells

Cancer biology & therapy, 2017-01, Vol.18 (1), p.16-25

2017

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The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer

PloS one, 2013-03, Vol.8 (3), p.e59380

2013

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Activating SRC mutation in a subset of advanced human colon cancers

Nature genetics, 1999-02, Vol.21 (2), p.187-190

1999

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Epidermal growth factor receptor revisited: Prognostic marker or target for therapy?

Cancer biology & therapy, 2010-09, Vol.10 (5), p.422-424

Irby, Rosalyn B.

2010

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Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NFκB and microRNA network

Molecular cancer, 2010-04, Vol.9 (1), p.98-98, Article 98

2010

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Correction: The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer

PloS one, 2013-11, Vol.8 (11)

2013

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Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU

Cancer biology & therapy, 2009-10, Vol.8 (19), p.1831-1837

2009

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Role of Src expression and activation in human cancer

Oncogene, 2000-11, Vol.19 (49), p.5636-5642

2000

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Identification of Src transformation fingerprint in human colon cancer

Oncogene, 2002-10, Vol.21 (47), p.7256-7265

2002

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The Akt Inhibitor ISC-4 Activates Prostate Apoptosis Response Protein-4 and Reduces Colon Tumor Growth in a Nude Mouse Model

Clinical cancer research, 2011-07, Vol.17 (13), p.4474-4483

2011

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Tyrosine Kinase Update: Role and Response in Cancer Therapy

Current cancer therapy reviews, 2011-05, Vol.7 (2), p.155-166

2011

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Iterative microarray and RNA interference-based interrogation of the Src-induced invasive phenotype

Cancer research (Chicago, Ill.), 2005-03, Vol.65 (5), p.1814-1821

2005

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Par-4 as a potential target for cancer therapy

Expert opinion on therapeutic targets, 2013-01, Vol.17 (1), p.77-87

2013

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Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells

Cancer research (Chicago, Ill.), 2002-05, Vol.62 (9), p.2669-2674

2002

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The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU

Apoptosis (London), 2011-12, Vol.16 (12), p.1285-1294

2011

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Tumor Necrosis Factor α Induces p53 Up-regulated Modulator of Apoptosis Expression in Colorectal Cancer Cell Lines

Diseases of the colon & rectum, 2010-03, Vol.53 (3), p.257-263

2010

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Osteopontin induces multiple changes in gene expression that reflect the six "hallmarks of cancer" in a model of breast cancer progression

Molecular carcinogenesis, 2005-08, Vol.43 (4), p.225-236

2005

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Src kinase induces tumor formation in the c‐SRC C57BL/6 mouse

International journal of cancer, 2008-06, Vol.122 (12), p.2665-2673

2008

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Seroreactivity to LGL leukemia-specific epitopes in aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria: Results of a bone marrow failure consortium study

Leukemia research, 2012-05, Vol.36 (5), p.581-587

2012

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Src activity alters α3 integrin expression in colon tumor cells

Clinical & experimental metastasis, 2009-02, Vol.26 (2), p.77-87

2009

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Primary cell lines: false representation or model system? a comparison of four human colorectal tumors and their coordinately established cell lines

International journal of clinical and experimental medicine, 2010-02, Vol.3 (1), p.69-83

2010

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Par-4: how far will it go?

AME medical journal, 2017-11, Vol.2, p.174-174

Irby, Rosalyn B.

2017

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Peroxisome proliferator-activated receptor α induces rat sterol carrier protein x promoter activity through two peroxisome proliferator-response elements

Molecular and cellular endocrinology, 2003-07, Vol.205 (1), p.169-184

2003

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Abstract 1166: Identification of a novel quinoxaline-isoselenourea targeting STAT3 pathway as a potential melanoma therapeutic

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1166-1166

2017

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Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway

TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells

The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer

Activating SRC mutation in a subset of advanced human colon cancers

Epidermal growth factor receptor revisited: Prognostic marker or target for therapy?

Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NFκB and microRNA network

Correction: The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer

Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU

Role of Src expression and activation in human cancer

Identification of Src transformation fingerprint in human colon cancer

The Akt Inhibitor ISC-4 Activates Prostate Apoptosis Response Protein-4 and Reduces Colon Tumor Growth in a Nude Mouse Model

Tyrosine Kinase Update: Role and Response in Cancer Therapy

Iterative microarray and RNA interference-based interrogation of the Src-induced invasive phenotype

Par-4 as a potential target for cancer therapy

Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells

The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU

Tumor Necrosis Factor α Induces p53 Up-regulated Modulator of Apoptosis Expression in Colorectal Cancer Cell Lines

Osteopontin induces multiple changes in gene expression that reflect the six "hallmarks of cancer" in a model of breast cancer progression

Src kinase induces tumor formation in the c‐SRC C57BL/6 mouse

Seroreactivity to LGL leukemia-specific epitopes in aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria: Results of a bone marrow failure consortium study

Src activity alters α3 integrin expression in colon tumor cells

Primary cell lines: false representation or model system? a comparison of four human colorectal tumors and their coordinately established cell lines

Par-4: how far will it go?

Peroxisome proliferator-activated receptor α induces rat sterol carrier protein x promoter activity through two peroxisome proliferator-response elements

Abstract 1166: Identification of a novel quinoxaline-isoselenourea targeting STAT3 pathway as a potential melanoma therapeutic

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