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The systemic delivery of an oncolytic adenovirus expressing decorin inhibits bone metastasis in a mouse model of human prostate cancer

Gene therapy, 2015-03, Vol.22 (3), p.247-256

2015

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Phenotypic Effects of Biglycan Deficiency Are Linked to Collagen Fibril Abnormalities, Are Synergized by Decorin Deficiency, and Mimic Ehlers‐Danlos‐Like Changes in Bone and Other Connective Tissues

Journal of bone and mineral research, 2002-07, Vol.17 (7), p.1180-1189

2002

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Achilles tendons from decorin- and biglycan-null mouse models have inferior mechanical and structural properties predicted by an image-based empirical damage model

Journal of biomechanics, 2015-07, Vol.48 (10), p.2110-2115

2015

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A role for decorin in controlling proliferation, adhesion, and migration of murine embryonic fibroblasts

Journal of biomedical materials research. Part A, 2010-05, Vol.93A (2), p.419-428

2010

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MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer

Oncogene, 2009-01, Vol.28 (2), p.257-269

2009

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A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity

Oncogene, 2007-01, Vol.26 (3), p.368-381

2007

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Differentiated activities of decorin and biglycan in the progression of post-traumatic osteoarthritis

Osteoarthritis and cartilage, 2021-08, Vol.29 (8), p.1181-1192

2021

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Targeted disruption of two small leucine-rich proteoglycans, biglycan and decorin, excerpts divergent effects on enamel and dentin formation

Calcified tissue international, 2005-11, Vol.77 (5), p.297-310

2005

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The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins

The Journal of biological chemistry, 1999-07, Vol.274 (27), p.18843-18846

Iozzo, R V

1999

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MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function

Annual review of biochemistry, 1998-01, Vol.67 (1), p.609-652

Iozzo, Renato V

1998

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Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo

The Journal of biological chemistry, 2000-10, Vol.275 (42), p.32879-32887

2000

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Heparan sulfate proteoglycans: intricate molecules with intriguing functions

The Journal of clinical investigation, 2001-07, Vol.108 (2), p.165-167

Iozzo, R V

2001

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Pancreatic injury in rats induced by fatty acid ethyl ester, a nonoxidative metabolite of alcohol

Gastroenterology (New York, N.Y. 1943), 1997-07, Vol.113 (1), p.286-294

1997

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Perlecan heparan sulfate proteoglycan: a novel receptor that mediates a distinct pathway for ligand catabolism

The Journal of biological chemistry, 2000-08, Vol.275 (33), p.25742

2000

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Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo

The Journal of clinical investigation, 1998-10, Vol.102 (8), p.1599-1608

1998

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Primary structure of the human heparan sulfate proteoglycan from basement membrane (HSPG2/perlecan). A chimeric molecule with multiple domains homologous to the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor

The Journal of biological chemistry, 1992-04, Vol.267 (12), p.8544-8557

1992

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The syndecan family of proteoglycans. Novel receptors mediating internalization of atherogenic lipoproteins in vitro

The Journal of clinical investigation, 1997-09, Vol.100 (6), p.1611-1622

1997

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Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases

The Journal of clinical investigation, 1997-07, Vol.100 (1), p.149-157

1997

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Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena

The Journal of clinical investigation, 2001-08, Vol.108 (3), p.349-355

2001

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Tumor stroma as a regulator of neoplastic behavior. Agonistic and antagonistic elements embedded in the same connective tissue

Laboratory investigation, 1995-08, Vol.73 (2), p.157

Iozzo, R V

1995

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Widespread expression of perlecan proteoglycan in basement membranes and extracellular matrices of human tissues as detected by a novel monoclonal antibody against domain III and by in situ hybridization

The journal of histochemistry and cytochemistry, 1994-02, Vol.42 (2), p.239-249

1994

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Decorin prevents metastatic spreading of breast cancer

Oncogene, 2005-02, Vol.24 (6), p.1104-1110

2005

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Fibroblast growth factor-2

The international journal of biochemistry & cell biology, 2000-02, Vol.32 (2), p.115-120

2000

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De novo Decorin Gene Expression Suppresses the Malignant Phenotype in Human Colon Cancer Cells

Proceedings of the National Academy of Sciences - PNAS, 1995-07, Vol.92 (15), p.7016-7020

1995

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Aberrant expression of the growth factor Wnt-5A in human malignancy

Cancer research (Chicago, Ill.), 1995-08, Vol.55 (16), p.3495-3499

1995

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The systemic delivery of an oncolytic adenovirus expressing decorin inhibits bone metastasis in a mouse model of human prostate cancer

Phenotypic Effects of Biglycan Deficiency Are Linked to Collagen Fibril Abnormalities, Are Synergized by Decorin Deficiency, and Mimic Ehlers‐Danlos‐Like Changes in Bone and Other Connective Tissues

Achilles tendons from decorin- and biglycan-null mouse models have inferior mechanical and structural properties predicted by an image-based empirical damage model

A role for decorin in controlling proliferation, adhesion, and migration of murine embryonic fibroblasts

MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer

A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity

Differentiated activities of decorin and biglycan in the progression of post-traumatic osteoarthritis

Targeted disruption of two small leucine-rich proteoglycans, biglycan and decorin, excerpts divergent effects on enamel and dentin formation

The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins

MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function

Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo

Heparan sulfate proteoglycans: intricate molecules with intriguing functions

Pancreatic injury in rats induced by fatty acid ethyl ester, a nonoxidative metabolite of alcohol

Perlecan heparan sulfate proteoglycan: a novel receptor that mediates a distinct pathway for ligand catabolism

Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo

Primary structure of the human heparan sulfate proteoglycan from basement membrane (HSPG2/perlecan). A chimeric molecule with multiple domains homologous to the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor

The syndecan family of proteoglycans. Novel receptors mediating internalization of atherogenic lipoproteins in vitro

Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases

Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena

Tumor stroma as a regulator of neoplastic behavior. Agonistic and antagonistic elements embedded in the same connective tissue

Widespread expression of perlecan proteoglycan in basement membranes and extracellular matrices of human tissues as detected by a novel monoclonal antibody against domain III and by in situ hybridization

Decorin prevents metastatic spreading of breast cancer

Fibroblast growth factor-2

De novo Decorin Gene Expression Suppresses the Malignant Phenotype in Human Colon Cancer Cells

Aberrant expression of the growth factor Wnt-5A in human malignancy

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