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Design, Synthesis and Stability of N-Acyloxymethyl- and N-Aminocarbonyloxymethyl-2-azetidinones as Human Leukocyte Elastase Inhibitors

Bioorganic & medicinal chemistry letters, 2001-04, Vol.11 (8), p.1065-1068

2001

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Metabolism of primaquine by liver homogenate fractions. Evidence for monoamine oxidase and cytochrome P450 involvement in the oxidative deamination of primaquine to carboxyprimaquine

Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, 1999-07, Vol.51 (4-5), p.299-303

1999

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Inactivation of rat liver cytochrome P450 (P450) by N, N-dimethylformamide and N, N-dimethylacetamide

Toxicology letters, 2001-10, Vol.124 (1), p.101-111

2001

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Structure-activity Studies of the Binding of the Flavonoid Scaffold to DNA

Anticancer research, 2009-06, Vol.29 (6), p.2285-2293

2009

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The Characterisation of Flavone-DNA Isoform Interactions as a Basis for Anticancer Drug Development

Anticancer research, 2009-06, Vol.29 (6), p.2273-2283

2009

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Imidazolidin-4-one Derivatives of Primaquine as Novel Transmission-Blocking Antimalarials

Journal of medicinal chemistry, 2005-02, Vol.48 (3), p.888-892

2005

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Synthesis of imidazolidin-4-one and 1H-imidazo[2,1-a]isoindole-2,5(3H,9bH)-dione derivatives of primaquine: scope and limitations

Tetrahedron, 2004-06, Vol.60 (26), p.5551-5562

2004

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Synthesis by conjugate radical addition of new heterocyclic amino acids with nucleic acid bases in their side chains

Chemical communications (Cambridge, England), 2000-01 (21), p.2131-2132

2000

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Effect of particle size and porosity on particle film coatings

Powder technology, 1991, Vol.65 (1), p.441-445

Iley, W.J.

1991

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Amidomethylation of amodiaquine: antimalarial N-Mannich base derivatives

Tetrahedron letters, 2004-10, Vol.45 (41), p.7663-7666

2004

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Teaching open and reproducible scholarship: a critical review of the evidence base for current pedagogical methods and their outcomes

Royal Society open science, 2023-05, Vol.10 (5), p.221255-221255

2023

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Oxidation of the methyl groups of N,N-dimethylbenzamides by a cytochrome P450 mono-oxygenase model system

Tetrahedron letters, 1990, Vol.31 (34), p.4921-4922

1990

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Metabolism of primaquine by liver homogenate fractions

Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, 1999-07, Vol.51 (4), p.299-303

1999

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Kinetics and Mechanism of Hydrolysis of N-Acyloxymethyl Derivatives of Azetidin-2-one

Journal of organic chemistry, 2004-05, Vol.69 (10), p.3359-3367

2004

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Triazene drug metabolites. Part 17 : Synthesis and plasma hydrolysis of acyloxymethyl carbamate derivatives of antitumour triazenes

Bioorganic & medicinal chemistry, 2000-07, Vol.8 (7), p.1719-1725

2000

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Kinetics and mechanism of hydrolysis of benzimidazolylcarbamates

Journal of the Brazilian Chemical Society, 2007, Vol.18 (1), p.171-178

2007

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Acyloxymethyl as a drug protecting group. Part 6 : N-acyloxymethyl-and N-[(aminocarbonyloxy)methyl]sulfonamides as prodrugs of agents containing a secondary sulfonamide group

Bioorganic & medicinal chemistry, 2000-04, Vol.8 (4), p.707-716

2000

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Acyloxymethyl as a drug protecting group: Part 4. The hydrolysis of tertiary amidomethyl ester prodrugs of carboxylic acid agents

Pharmaceutical research, 1997-11, Vol.14 (11), p.1634-1639

1997

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Microsomal metabolism of N,N-diethyl-m-toluamide (DEET,DET): the extended network of metabolites

Xenobiotica, 1999, Vol.29 (4), p.409-416

1999

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Synthesis, Stability and In Vitro Dermal Evaluation of Aminocarbonyloxymethyl Esters as Prodrugs of Carboxylic Acid Agents

Bioorganic & medicinal chemistry, 2002-03, Vol.10 (3), p.809-816

2002

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Dipeptide derivatives of primaquine as transmission-blocking antimalarials : Effect of aliphatic side-chain acylation on the gametocytocidal activity and on the formation of carboxyprimaquine in rat liver homogenates

Pharmaceutical research, 1999-06, Vol.16 (6), p.949-955

1999

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Development of anti-MUC1 DNA aptamers for the imaging and radiotherapy of breast cancer

Breast cancer research : BCR, 2008-01, Vol.10 (S2), p.P62-P62, Article P62

2008

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211 POSTER Design of an anti MUC1 DNA aptamer as novel radiopharmaceutical for the diagnostic imaging and targeted radiotherapy of tumours

European journal of cancer supplements, 2006-11, Vol.4 (12), p.65-66

2006

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Synthesis by conjugate radical addition of new heterocyclic amino acids with nucleobase side chains

Tetrahedron, 2001-07, Vol.57 (30), p.6539-6555

2001

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Cleavage of tertiary amidomethyl ester prodrugs of carboxylic acids by rat liver homogenates

European journal of pharmaceutical sciences, 1999-12, Vol.9 (2), p.201-205

1999

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Design, Synthesis and Stability of N-Acyloxymethyl- and N-Aminocarbonyloxymethyl-2-azetidinones as Human Leukocyte Elastase Inhibitors

Metabolism of primaquine by liver homogenate fractions. Evidence for monoamine oxidase and cytochrome P450 involvement in the oxidative deamination of primaquine to carboxyprimaquine

Inactivation of rat liver cytochrome P450 (P450) by N, N-dimethylformamide and N, N-dimethylacetamide

Structure-activity Studies of the Binding of the Flavonoid Scaffold to DNA

The Characterisation of Flavone-DNA Isoform Interactions as a Basis for Anticancer Drug Development

Imidazolidin-4-one Derivatives of Primaquine as Novel Transmission-Blocking Antimalarials

Synthesis of imidazolidin-4-one and 1H-imidazo[2,1-a]isoindole-2,5(3H,9bH)-dione derivatives of primaquine: scope and limitations

Synthesis by conjugate radical addition of new heterocyclic amino acids with nucleic acid bases in their side chains

Effect of particle size and porosity on particle film coatings

Amidomethylation of amodiaquine: antimalarial N-Mannich base derivatives

Teaching open and reproducible scholarship: a critical review of the evidence base for current pedagogical methods and their outcomes

Oxidation of the methyl groups of N,N-dimethylbenzamides by a cytochrome P450 mono-oxygenase model system

Metabolism of primaquine by liver homogenate fractions

Kinetics and Mechanism of Hydrolysis of N-Acyloxymethyl Derivatives of Azetidin-2-one

Triazene drug metabolites. Part 17 : Synthesis and plasma hydrolysis of acyloxymethyl carbamate derivatives of antitumour triazenes

Kinetics and mechanism of hydrolysis of benzimidazolylcarbamates

Acyloxymethyl as a drug protecting group. Part 6 : N-acyloxymethyl-and N-[(aminocarbonyloxy)methyl]sulfonamides as prodrugs of agents containing a secondary sulfonamide group

Acyloxymethyl as a drug protecting group: Part 4. The hydrolysis of tertiary amidomethyl ester prodrugs of carboxylic acid agents

Microsomal metabolism of N,N-diethyl-m-toluamide (DEET,DET): the extended network of metabolites

Synthesis, Stability and In Vitro Dermal Evaluation of Aminocarbonyloxymethyl Esters as Prodrugs of Carboxylic Acid Agents

Dipeptide derivatives of primaquine as transmission-blocking antimalarials : Effect of aliphatic side-chain acylation on the gametocytocidal activity and on the formation of carboxyprimaquine in rat liver homogenates

Development of anti-MUC1 DNA aptamers for the imaging and radiotherapy of breast cancer

211 POSTER Design of an anti MUC1 DNA aptamer as novel radiopharmaceutical for the diagnostic imaging and targeted radiotherapy of tumours

Synthesis by conjugate radical addition of new heterocyclic amino acids with nucleobase side chains

Cleavage of tertiary amidomethyl ester prodrugs of carboxylic acids by rat liver homogenates

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