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Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

British journal of pharmacology, 2006-07, Vol.148 (5), p.619-628

2006

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The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids

The Journal of biological chemistry, 2003-03, Vol.278 (13), p.11312-11319

2003

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Molecular Identification of High and Low Affinity Receptors for Nicotinic Acid

The Journal of biological chemistry, 2003-03, Vol.278 (11), p.9869-9874

2003

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Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an Acute Respiratory Distress Syndrome Model

American journal of respiratory and critical care medicine, 2024-03, Vol.209 (6), p.703-715

2024

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Potent, Selective, and Orally Efficacious Antagonists of Melanin-Concentrating Hormone Receptor 1

Journal of medicinal chemistry, 2006-11, Vol.49 (24), p.7095-7107

2006

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The Effect of PPARα, PPARδ, PPARγ, and PPARpan Agonists on Body Weight, Body Mass, and Serum Lipid Profiles in Diet-Induced Obese AKR/J Mice

PPAR Research, 2007, Vol.2007, p.401-413

2007

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Lysosomes contribute to anomalous pharmacokinetic behavior of melanocortin-4 receptor agonists

Pharmaceutical research, 2007-06, Vol.24 (6), p.1138-1144

2007

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Opioid Receptor Modulation of Hedonic Taste Preference and Food Intake: A Single-Dose Safety, Pharmacokinetic, and Pharmacodynamic Investigation With GSK1521498, a Novel μ-Opioid Receptor Inverse Agonist

Journal of clinical pharmacology, 2012-04, Vol.52 (4), p.464-474

2012

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Characterisation of olanzapine-induced weight gain and effect of aripiprazole vs olanzapine on body weight and prolactin secretion in female rats

Psychopharmacologia, 2005-10, Vol.182 (2), p.220-231

2005

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The discovery and optimization of pyrimidinone-containing MCH R1 antagonists

Bioorganic & medicinal chemistry letters, 2006-09, Vol.16 (18), p.4723-4727

2006

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A concise synthesis of 1,4-dihydro-[1,4]diazepine-5,7-dione, a novel 7-TM receptor ligand core structure with melanocortin receptor agonist activity

Bioorganic & medicinal chemistry, 2010-03, Vol.18 (5), p.1822-1833

2010

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Selection of an Optimal Reporter Gene for Cell-Based High Throughput Screening Assays

SLAS discovery, 1997-02, Vol.2 (1), p.7-9

1997

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Novel benzimidazole-based MCH R1 antagonists

Bioorganic & medicinal chemistry letters, 2006-10, Vol.16 (19), p.4994-5000

2006

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6-(4-Chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3H)-one-Based Melanin-Concentrating Hormone Receptor 1 Antagonist

Journal of medicinal chemistry, 2006-11, Vol.49 (24), p.7108-7118

2006

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The Orphan G Protein-coupled Receptor GPR40 Is Activated by Medium and Long Chain Fatty Acids

The Journal of biological chemistry, 2003-03, Vol.278 (13), p.11303-11311

2003

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Regulation of TNF-α secretion by a specific melanocortin-1 receptor peptide agonist

Peptides (New York, N.Y. : 1980), 2003-05, Vol.24 (5), p.709-716

2003

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Coupling of Dual Signaling Pathways: Epidermal Growth Factor Action Involves the Estrogen Receptor

Proceedings of the National Academy of Sciences - PNAS, 1992-05, Vol.89 (10), p.4658-4662

1992

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Regulation of Ingestive Behaviors in the Rat by GSK1521498, a Novel μ-Opioid Receptor-Selective Inverse Agonist

The Journal of pharmacology and experimental therapeutics, 2011-10, Vol.339 (1), p.24-34

2011

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Development of a facile method for high throughput screening with reporter gene assays

Journal of biomolecular screening, 2000-10, Vol.5 (5), p.377-384

2000

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Characterization of Melanocortin Receptors

Current Protocols in Pharmacology, 2003-11, Vol.22 (1), p.1.28.1-1.28.8

2003

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A combination assay for simultaneous assessment of multiple signaling pathways

Journal of pharmacological and toxicological methods, 1999-12, Vol.42 (4), p.225-235

1999

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Peptide growth factors elicit estrogen receptor-dependent transcriptional activation of an estrogen-responsive element

Molecular endocrinology (Baltimore, Md.), 1993-08, Vol.7 (8), p.992-998

1993

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Peptide growth factor cross-talk with the estrogen receptor requires the A/B domain and occurs independently of protein kinase C or estradiol

Endocrinology (Philadelphia), 1996-05, Vol.137 (5), p.1735-1744

1996

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A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma

Pharmacogenetics (London), 2004-09, Vol.14 (9), p.627-633

2004

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Regulation of ingestive behaviors in the rat by GSK1521498, a novel micro-opioid receptor-selective inverse agonist

The Journal of pharmacology and experimental therapeutics, 2011-10, Vol.339 (1), p.24

2011

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Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids

Molecular Identification of High and Low Affinity Receptors for Nicotinic Acid

Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an Acute Respiratory Distress Syndrome Model

Potent, Selective, and Orally Efficacious Antagonists of Melanin-Concentrating Hormone Receptor 1

The Effect of PPARα, PPARδ, PPARγ, and PPARpan Agonists on Body Weight, Body Mass, and Serum Lipid Profiles in Diet-Induced Obese AKR/J Mice

Lysosomes contribute to anomalous pharmacokinetic behavior of melanocortin-4 receptor agonists

Opioid Receptor Modulation of Hedonic Taste Preference and Food Intake: A Single-Dose Safety, Pharmacokinetic, and Pharmacodynamic Investigation With GSK1521498, a Novel μ-Opioid Receptor Inverse Agonist

Characterisation of olanzapine-induced weight gain and effect of aripiprazole vs olanzapine on body weight and prolactin secretion in female rats

The discovery and optimization of pyrimidinone-containing MCH R1 antagonists

A concise synthesis of 1,4-dihydro-[1,4]diazepine-5,7-dione, a novel 7-TM receptor ligand core structure with melanocortin receptor agonist activity

Selection of an Optimal Reporter Gene for Cell-Based High Throughput Screening Assays

Novel benzimidazole-based MCH R1 antagonists

6-(4-Chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3H)-one-Based Melanin-Concentrating Hormone Receptor 1 Antagonist

The Orphan G Protein-coupled Receptor GPR40 Is Activated by Medium and Long Chain Fatty Acids

Regulation of TNF-α secretion by a specific melanocortin-1 receptor peptide agonist

Coupling of Dual Signaling Pathways: Epidermal Growth Factor Action Involves the Estrogen Receptor

Regulation of Ingestive Behaviors in the Rat by GSK1521498, a Novel μ-Opioid Receptor-Selective Inverse Agonist

Development of a facile method for high throughput screening with reporter gene assays

Characterization of Melanocortin Receptors

A combination assay for simultaneous assessment of multiple signaling pathways

Peptide growth factors elicit estrogen receptor-dependent transcriptional activation of an estrogen-responsive element

Peptide growth factor cross-talk with the estrogen receptor requires the A/B domain and occurs independently of protein kinase C or estradiol

A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma

Regulation of ingestive behaviors in the rat by GSK1521498, a novel micro-opioid receptor-selective inverse agonist

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