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Synthesis of Diazepinones via Intramolecular Transamidation

Organic letters, 2004-09, Vol.6 (19), p.3361-3364

2004

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Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease

Journal of medicinal chemistry, 2010-09, Vol.53 (18), p.6653-6680

2010

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Contribution of indazolinone tautomers to kinase activity

Bioorganic & medicinal chemistry letters, 2012-07, Vol.22 (14), p.4502-4505

2012

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Synthesis and Structure−Activity Relationships of β- and α-Piperidine Sulfone Hydroxamic Acid Matrix Metalloproteinase Inhibitors with Oral Antitumor Efficacy

Journal of medicinal chemistry, 2005-10, Vol.48 (21), p.6713-6730

2005

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Pyrrolizidine Esters and Amides as 5-HT4 Receptor Agonists and Antagonists

Journal of medicinal chemistry, 2006-02, Vol.49 (3), p.1125-1139

2006

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MMP-13 selective α-sulfone hydroxamates: A survey of P1′ heterocyclic amide isosteres

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (10), p.2820-2822

2011

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SC-53116: the first selective agonist at the newly identified serotonin 5-HT4 receptor subtype

Journal of medicinal chemistry, 1992-04, Vol.35 (8), p.1486-1489

1992

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Bridgehead-methyl analog of SC-53116 as a 5-HT4 agonist

Bioorganic & medicinal chemistry letters, 2004-06, Vol.14 (12), p.3073-3075

2004

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α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (20), p.2719-2722

2001

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Selective, orally active MMP inhibitors with an aryl backbone

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (18), p.2481-2483

2001

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Synthesis and activity of selective MMP inhibitors with an aryl backbone

Bioorganic & medicinal chemistry letters, 2000-12, Vol.10 (24), p.2815-2817

2000

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1,3,4-trisubstituted pyrrolidinones as scaffolds for construction of peptidomimetic cholecystokinin antagonists

Bioorganic & medicinal chemistry letters, 1992-10, Vol.2 (10), p.1251-1256

1992

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Pyrrolizidine Esters and Amides as 5-HT 4 Receptor Agonists and Antagonists

Journal of medicinal chemistry, 2006-02, Vol.49 (3), p.1125-1139

2006

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Enantioselective synthesis of dual [formula omitted] serotonergic azanoradamantane SC-52491

Tetrahedron, 1999-10, Vol.55 (40), p.11787-11802

1999

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Serotonin 5-HT4 agonist activity of a series of meso-azanoradamantane benzamides

Bioorganic & medicinal chemistry letters, 1997-09, Vol.7 (17), p.2149-2154

1997

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Serotonin 5-HT 4 agonist activity of a series of meso-azanoradamantane benzamides

Bioorganic & medicinal chemistry letters, 1997, Vol.7 (17), p.2149-2154

1997

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(Acyloxy)benzophenones and (acyloxy)-4-pyrones. A new class of inhibitors of human neutrophil elastase

Journal of medicinal chemistry, 1988-05, Vol.31 (5), p.1052-1061

1988

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Synthesis of Diazepinones via Intramolecular Transamidation

ChemInform, 2005-01, Vol.36 (2), p.no-no

2005

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Bridgehead-Methyl Analogue of SC-53116 as a 5-HT4 Agonist

ChemInform, 2004-09, Vol.35 (39), p.no-no

2004

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The herpesvirus protease: mechanistic studies and discovery of inhibitors of the human cytomegalovirus protease

Drug design and discovery, 1997-05, Vol.15 (1), p.3

1997

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(Acyloxy)benzophenones and (acyloxy)-4-pyrones. A new class of inhibitors of human neutrophil elastase

Journal of medicinal chemistry, 1988-05, Vol.31 (5), p.1052-1061

1988

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ChemInform Abstract: Selective, Orally Active MMP Inhibitors with an Aryl Backbone

ChemInform, 2001-12, Vol.32 (50), p.no-no

2001

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Design and synthesis of agonists and antagonists of the serotonin 5-HT4 receptor subtype

Perspectives in Receptor Research, 1996, Vol.24, p.99-120

1996

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Marine Actinobacteria a New Source of Antibacterial Metabolites to Treat Acne Vulgaris Disease—A Systematic Literature Review

Antibiotics (Basel), 2022-07, Vol.11 (7), p.965

2022

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An unusual case of heart failure due to ANCA‐negative vasculitis: A case report and focused review of the literature

Clinical case reports, 2023-08, Vol.11 (8), p.e7749-n/a

2023

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Synthesis of Diazepinones via Intramolecular Transamidation

Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease

Contribution of indazolinone tautomers to kinase activity

Synthesis and Structure−Activity Relationships of β- and α-Piperidine Sulfone Hydroxamic Acid Matrix Metalloproteinase Inhibitors with Oral Antitumor Efficacy

Pyrrolizidine Esters and Amides as 5-HT4 Receptor Agonists and Antagonists

MMP-13 selective α-sulfone hydroxamates: A survey of P1′ heterocyclic amide isosteres

SC-53116: the first selective agonist at the newly identified serotonin 5-HT4 receptor subtype

Bridgehead-methyl analog of SC-53116 as a 5-HT4 agonist

α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1

Selective, orally active MMP inhibitors with an aryl backbone

Synthesis and activity of selective MMP inhibitors with an aryl backbone

1,3,4-trisubstituted pyrrolidinones as scaffolds for construction of peptidomimetic cholecystokinin antagonists

Pyrrolizidine Esters and Amides as 5-HT 4 Receptor Agonists and Antagonists

Enantioselective synthesis of dual [formula omitted] serotonergic azanoradamantane SC-52491

Serotonin 5-HT4 agonist activity of a series of meso-azanoradamantane benzamides

Serotonin 5-HT 4 agonist activity of a series of meso-azanoradamantane benzamides

(Acyloxy)benzophenones and (acyloxy)-4-pyrones. A new class of inhibitors of human neutrophil elastase

Synthesis of Diazepinones via Intramolecular Transamidation

Bridgehead-Methyl Analogue of SC-53116 as a 5-HT4 Agonist

The herpesvirus protease: mechanistic studies and discovery of inhibitors of the human cytomegalovirus protease

(Acyloxy)benzophenones and (acyloxy)-4-pyrones. A new class of inhibitors of human neutrophil elastase

ChemInform Abstract: Selective, Orally Active MMP Inhibitors with an Aryl Backbone

Design and synthesis of agonists and antagonists of the serotonin 5-HT4 receptor subtype

Marine Actinobacteria a New Source of Antibacterial Metabolites to Treat Acne Vulgaris Disease—A Systematic Literature Review

An unusual case of heart failure due to ANCA‐negative vasculitis: A case report and focused review of the literature

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