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Endocytosis of GPI-Linked Membrane Folate Receptor-α

The Journal of cell biology, 1996-01, Vol.132 (1/2), p.35-47

1996

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Structure-activity and structure-selectivity studies on diaminoquinazolines and other inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase

Antimicrobial Agents and Chemotherapy, 1995-01, Vol.39 (1), p.79-86

1995

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Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity

Molecular pharmacology, 1995-09, Vol.48 (3), p.459

1995

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Inhibition of hog liver folylpolyglutamate synthetase by 5-substituted 5,8-dideaza analogs of folic acid bearing a terminal L-ornithine residue

Journal of medicinal chemistry, 1992-10, Vol.35 (22), p.4078-4085

1992

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Studies on the antitumor effects of analogues of 5,8-dideazaisofolic acid and 5,8-dideazaisoaminopterin

Biochemical pharmacology, 1995-09, Vol.50 (6), p.803-809

1995

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Synthesis and biological evaluation of a fluorescent analog of folic acid

Biochemistry (Easton), 1991-06, Vol.30 (23), p.5674-5681

1991

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Synthesis of 5-chloro-5,8-dideaza analogs of folic acid and aminopterin targeted for colon adenocarcinoma

Journal of medicinal chemistry, 1987-08, Vol.30 (8), p.1515-1519

1987

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Inhibition of mammalian folylpolyglutamate synthetase and human dihydrofolate reductase by 5,8-dideaza analogs of folic acid and aminopterin bearing a terminal L-ornithine

Journal of medicinal chemistry, 1989-07, Vol.32 (7), p.1559-1565

1989

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Mechanism of action of 5,8-dideazaisofolic acid and other quinazoline antifols in human colon carcinoma cells

Cancer research (Chicago, Ill.), 1987-11, Vol.47 (22), p.5975-5981

1987

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Studies on the mechanism of antitumor action of 2-desamino-2-methyl-5,8-dideazaisofolic acid

Biochemical pharmacology, 1991-03, Vol.41 (5), p.781-787

1991

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Chemistry and antitumor evaluation of selected classical 2,4-diaminoquinazoline analogs of folic acid

Journal of medicinal chemistry, 1985-02, Vol.28 (2), p.209-215

1985

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Improved synthesis and antitumor evaluation of 5,8-dideazaisofolic acid and closely related analogs

Journal of medicinal chemistry, 1984-02, Vol.27 (2), p.232-235

1984

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Comparison of the biological effects of selected 5,8-dideazafolate analogs with their 2-desamino counterparts

Journal of medicinal chemistry, 1989-04, Vol.32 (4), p.852-856

1989

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Inhibition of murine thymidylate synthase and human dihydrofolate reductase by 5,8-dideaza analogs of folic acid and aminopterin

Journal of medicinal chemistry, 1988-02, Vol.31 (2), p.449-454

1988

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Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorin

Biochemical pharmacology, 1989-08, Vol.38 (16), p.2677-2684

1989

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Purification and characterization of dihydrofolate reductase from soybean seedlings

Archives of biochemistry and biophysics, 1987-06, Vol.255 (2), p.279-289

1987

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Quinazoline Analogues of Folic Acid as Inhibitors of Thymidylate Synthetase from Bacterial and Mammalian Sources

Molecular pharmacology, 1979-07, Vol.16 (1), p.261-269

1979

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Folate analogs as inhibitors of thymidylate synthase

Journal of medicinal chemistry, 1987-04, Vol.30 (4), p.675-678

1987

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Further studies on substituted quinazolines and triazines as inhibitors of a methotrexate-insensitive murine dihydrofolate reductase

Biochemical pharmacology, 1986-04, Vol.35 (7), p.1143-1147

1986

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Effects of 5,8-dideazaisopteroylglutamate (IAHQ) on L1210 leukemia in mice when given alone and in combination with methotrexate, probenecid, or verapamil

Cancer chemotherapy and pharmacology, 1986-01, Vol.18 (3), p.231-234

1986

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Substrate specificity of mammalian folylpoly-γ-glutamate synthetase for 5,8-dideazafolates and 5,8-dideaza analogues of aminopterin

Biochimica et biophysica acta, 1988-12, Vol.957 (3), p.363-369

1988

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Micellar high-performance liquid chromatographic determination of folylpolyglutamate hydrolase activity

Journal of Chromatography A, 1986, Vol.357 (1), p.183-189

1986

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Improved synthetic routes to 5,8-dideazapteroylglutamates amenable to the formation of poly-gamma-L-glutamyl derivatives

Advances in experimental medicine and biology, 1983, Vol.163, p.101

1983

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Effects of 5,8-dideazaisofolic acid (IAHQ) on human tumor cells in culture and on normal and tumor-bearing hamsters

Chemotherapy (Basel), 1982-01, Vol.28 (4), p.276-282

1982

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Synthesis and biological evaluation of analogues of 5,8-dideazaisofolic acid (IAHQ) modified at positions 2, 4 and 9

Advances in experimental medicine and biology, 1993, Vol.338, p.417

1993

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Endocytosis of GPI-Linked Membrane Folate Receptor-α

Structure-activity and structure-selectivity studies on diaminoquinazolines and other inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase

Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity

Inhibition of hog liver folylpolyglutamate synthetase by 5-substituted 5,8-dideaza analogs of folic acid bearing a terminal L-ornithine residue

Studies on the antitumor effects of analogues of 5,8-dideazaisofolic acid and 5,8-dideazaisoaminopterin

Synthesis and biological evaluation of a fluorescent analog of folic acid

Synthesis of 5-chloro-5,8-dideaza analogs of folic acid and aminopterin targeted for colon adenocarcinoma

Inhibition of mammalian folylpolyglutamate synthetase and human dihydrofolate reductase by 5,8-dideaza analogs of folic acid and aminopterin bearing a terminal L-ornithine

Mechanism of action of 5,8-dideazaisofolic acid and other quinazoline antifols in human colon carcinoma cells

Studies on the mechanism of antitumor action of 2-desamino-2-methyl-5,8-dideazaisofolic acid

Chemistry and antitumor evaluation of selected classical 2,4-diaminoquinazoline analogs of folic acid

Improved synthesis and antitumor evaluation of 5,8-dideazaisofolic acid and closely related analogs

Comparison of the biological effects of selected 5,8-dideazafolate analogs with their 2-desamino counterparts

Inhibition of murine thymidylate synthase and human dihydrofolate reductase by 5,8-dideaza analogs of folic acid and aminopterin

Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorin

Purification and characterization of dihydrofolate reductase from soybean seedlings

Quinazoline Analogues of Folic Acid as Inhibitors of Thymidylate Synthetase from Bacterial and Mammalian Sources

Folate analogs as inhibitors of thymidylate synthase

Further studies on substituted quinazolines and triazines as inhibitors of a methotrexate-insensitive murine dihydrofolate reductase

Effects of 5,8-dideazaisopteroylglutamate (IAHQ) on L1210 leukemia in mice when given alone and in combination with methotrexate, probenecid, or verapamil

Substrate specificity of mammalian folylpoly-γ-glutamate synthetase for 5,8-dideazafolates and 5,8-dideaza analogues of aminopterin

Micellar high-performance liquid chromatographic determination of folylpolyglutamate hydrolase activity

Improved synthetic routes to 5,8-dideazapteroylglutamates amenable to the formation of poly-gamma-L-glutamyl derivatives

Effects of 5,8-dideazaisofolic acid (IAHQ) on human tumor cells in culture and on normal and tumor-bearing hamsters

Synthesis and biological evaluation of analogues of 5,8-dideazaisofolic acid (IAHQ) modified at positions 2, 4 and 9

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