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Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation

Cancer biology & therapy, 2008-10, Vol.7 (10), p.1648-1662

2008

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Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes

Hepatology (Baltimore, Md.), 2005-12, Vol.42 (6), p.1291-1299

2005

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Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis

Molecular biology of the cell, 2001-09, Vol.12 (9), p.2629-2645

2001

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Multiple Cyclin Kinase Inhibitors Promote Bile Acid-induced Apoptosis and Autophagy in Primary Hepatocytes via p53-CD95-dependent Signaling

The Journal of biological chemistry, 2008-09, Vol.283 (36), p.24343-24358

2008

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Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes

Hepatology (Baltimore, Md.), 2002-04, Vol.35 (4), p.779-789

2002

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Regulation of autophagy by ceramide-CD95-PERK signaling

Autophagy, 2008-10, Vol.4 (7), p.929-931

2008

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Bile acids enhance the activity of the insulin receptor and glycogen synthase in primary rodent hepatocytes

Hepatology (Baltimore, Md.), 2004-02, Vol.39 (2), p.456-463

2004

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17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines

Molecular cancer therapeutics, 2007-02, Vol.6 (2), p.618-632

2007

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Astrocyte Elevated Gene-1 (AEG-1) Regulates Lipid Homeostasis

The Journal of biological chemistry, 2015-07, Vol.290 (29), p.18227-18236

2015

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Acid Sphingomyelinase Gene Deficiency Ameliorates the Hyperhomocysteinemia-Induced Glomerular Injury in Mice

The American journal of pathology, 2011-11, Vol.179 (5), p.2210-2219

2011

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Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling

The Journal of biological chemistry, 2016-09, Vol.291 (39), p.20823-20823

2016

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A longitudinal systems biology analysis of lactulose withdrawal in hepatic encephalopathy

Metabolic brain disease, 2012-06, Vol.27 (2), p.205-215

2012

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Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes

Molecular and Cellular Biology, 2003-05, Vol.23 (9), p.3052-3066

2003

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A potential role for resistant starch fermentation in modulating colonic bacterial metabolism and colon cancer risk

Cancer biology & therapy, 2006-03, Vol.5 (3), p.273-274

2006

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Cyclin kinase inhibitor p21 potentiates bile acid–induced apoptosis in hepatocytes that is dependent on p53

Hepatology (Baltimore, Md.), 2002-07, Vol.36 (1), p.39-48

2002

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Approaches for monitoring signal transduction changes in normal and cancer cells

Methods in molecular biology (Clifton, N.J.), 2007, Vol.383, p.259

2007

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Inhibition of insulin/IGF-1 receptor signaling enhances bile acid toxicity in primary hepatocytes

Biochemical pharmacology, 2005-11, Vol.70 (11), p.1685-1696

2005

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Conjugates of ursodeoxycholate protect against cytotoxicity of more hydrophobic bile salts: In vitro studies in rat hepatocytes and human erythrocytes

Hepatology (Baltimore, Md.), 1991-11, Vol.14 (5), p.920-926

1991

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Fas Ligand-dependent and -independent mechanisms of toxicity induced by T cell lymphomas in lymphoid organs and in the liver

Clinical immunology (Orlando, Fla.), 2003-11, Vol.109 (2), p.144-153

2003

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Regulation of p21 and p27 expression by the hepatitis B virus X protein and the alternate initiation site X proteins, AUG2 and AUG3

Journal of gastroenterology and hepatology, 2003-04, Vol.18 (4), p.376-385

2003

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Conjugated Bile Acids Regulate Hepatocyte Glycogen Synthase Activity In Vitro and In Vivo via Gα i Signaling

Molecular pharmacology, 2007-04, Vol.71 (4), p.1122-1128

2007

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Hepatitis B virus X protein increases expression of p21Cip-1/WAF1/MDA6 and p27Kip-1 in primary mouse hepatocytes, leading to reduced cell cycle progression

Hepatology (Baltimore, Md.), 2001-11, Vol.34 (5), p.906-917

2001

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A Role for Both Ets and C/EBP Transcription Factors and mRNA Stabilization in the MAPK-dependent Increase in p21 Cip-1/WAF1/mda6 Protein Levels in Primary Hepatocytes

Molecular biology of the cell, 2000-09, Vol.11 (9), p.2915-2932

2000

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Conjugated bile acids regulate hepatocyte glycogen synthase activity in vitro and in vivo via Galphai signaling

Molecular pharmacology, 2007-04, Vol.71 (4), p.1122-1128

2007

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Conjugated Bile Acids Regulate Hepatocyte Glycogen Synthase Activity In Vitro and In Vivo via GÎ±i Signaling

Molecular pharmacology, 2007-04, Vol.71 (4), p.1122

2007

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Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation

Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes

Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis

Multiple Cyclin Kinase Inhibitors Promote Bile Acid-induced Apoptosis and Autophagy in Primary Hepatocytes via p53-CD95-dependent Signaling

Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes

Regulation of autophagy by ceramide-CD95-PERK signaling

Bile acids enhance the activity of the insulin receptor and glycogen synthase in primary rodent hepatocytes

17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines

Astrocyte Elevated Gene-1 (AEG-1) Regulates Lipid Homeostasis

Acid Sphingomyelinase Gene Deficiency Ameliorates the Hyperhomocysteinemia-Induced Glomerular Injury in Mice

Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling

A longitudinal systems biology analysis of lactulose withdrawal in hepatic encephalopathy

Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes

A potential role for resistant starch fermentation in modulating colonic bacterial metabolism and colon cancer risk

Cyclin kinase inhibitor p21 potentiates bile acid–induced apoptosis in hepatocytes that is dependent on p53

Approaches for monitoring signal transduction changes in normal and cancer cells

Inhibition of insulin/IGF-1 receptor signaling enhances bile acid toxicity in primary hepatocytes

Conjugates of ursodeoxycholate protect against cytotoxicity of more hydrophobic bile salts: In vitro studies in rat hepatocytes and human erythrocytes

Fas Ligand-dependent and -independent mechanisms of toxicity induced by T cell lymphomas in lymphoid organs and in the liver

Regulation of p21 and p27 expression by the hepatitis B virus X protein and the alternate initiation site X proteins, AUG2 and AUG3

Conjugated Bile Acids Regulate Hepatocyte Glycogen Synthase Activity In Vitro and In Vivo via Gα i Signaling

Hepatitis B virus X protein increases expression of p21Cip-1/WAF1/MDA6 and p27Kip-1 in primary mouse hepatocytes, leading to reduced cell cycle progression

A Role for Both Ets and C/EBP Transcription Factors and mRNA Stabilization in the MAPK-dependent Increase in p21 Cip-1/WAF1/mda6 Protein Levels in Primary Hepatocytes

Conjugated bile acids regulate hepatocyte glycogen synthase activity in vitro and in vivo via Galphai signaling

Conjugated Bile Acids Regulate Hepatocyte Glycogen Synthase Activity In Vitro and In Vivo via GÎ±i Signaling

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