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Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus

Nature genetics, 2021-11, Vol.53 (11), p.1606-1615

2021

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Genomic diversity of SARS-CoV-2 in Oxford during United Kingdom’s first national lockdown

Scientific reports, 2021-11, Vol.11 (1), p.21484-21484, Article 21484

2021

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Lentiviral and AAV-mediated expression of palivizumab offer protection against Respiratory Syncytial Virus infection

Scientific reports, 2021-08, Vol.11 (1), p.15694-15694, Article 15694

2021

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Identification of AAV serotypes for lung gene therapy in human embryonic stem cell-derived lung organoids

Stem cell research & therapy, 2020-10, Vol.11 (1), p.1-448, Article 448

2020

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A human surfactant B deficiency air-liquid interface cell culture model suitable for gene therapy applications

Molecular therapy. Methods & clinical development, 2021-03, Vol.20, p.237-246

2021

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CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression

Nature biotechnology, 2008-05, Vol.26 (5), p.549-551

2008

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Intranasal Lentiviral Vector-Mediated Antibody Delivery Confers Reduction of SARS-CoV-2 Infection in Elderly and Immunocompromised Mice

Frontiers in immunology, 2022-04, Vol.13, p.819058-819058

2022

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A Phase I/IIa Safety and Efficacy Study of Nebulized Liposome-mediated Gene Therapy for Cystic Fibrosis Supports a Multidose Trial

American journal of respiratory and critical care medicine, 2015-12, Vol.192 (11), p.1389-1392

2015

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Sendai F/HN pseudotyped lentiviral vector transduces human ciliated and non-ciliated airway cells using α 2,3 sialylated receptors

Molecular therapy. Methods & clinical development, 2022-09, Vol.26, p.239-252

2022

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RNA-seq analysis of the human surfactant air-liquid interface culture reveals alveolar type II cell-like transcriptome

Molecular therapy. Methods & clinical development, 2022-03, Vol.24, p.62-70

2022

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Correction of a chronic pulmonary disease through lentiviral vector-mediated protein expression

Molecular therapy. Methods & clinical development, 2022-06, Vol.25, p.382-391

2022

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Lessons learned from lung and liver in-vivo gene therapy: implications for the future

Expert opinion on biological therapy, 2018-09, Vol.18 (9), p.959-972

2018

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Genome-wide integration site detection using Cas9 enriched amplification-free long-range sequencing

Nucleic acids research, 2021-02, Vol.49 (3), p.e16-e16

2021

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Aerosol delivery of DNA/liposomes to the lung for cystic fibrosis gene therapy

Human gene therapy. Clinical development, 2014-06, Vol.25 (2), p.97-107

2014

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CpG-free plasmid expression cassettes for cystic fibrosis gene therapy

Biomaterials, 2012-10, Vol.33 (28), p.6833-6842

2012

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Delivery of genes into the CF airway

Thorax, 2014-10, Vol.69 (10), p.962-964

2014

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Lung directed antibody gene transfer confers protection against SARS-CoV-2 infection

Thorax, 2022-12, Vol.77 (12), p.1229-1236

2022

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Progress in Respiratory Gene Therapy

Human gene therapy, 2022-09, Vol.33 (17-18), p.893-912

2022

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Type I interferon receptor signalling deficiency results in dysregulated innate immune responses to SARS‐CoV‐2 in mice

European journal of immunology, 2022-11, Vol.52 (11), p.1768-1775

2022

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Pharmacological Characterization of a Novel ENaCα siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis

Molecular therapy. Nucleic acids, 2013-01, Vol.2 (1), p.e65-e65, Article e65

2013

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Lack of Repeat Transduction by Recombinant Adeno-Associated Virus Type 5/5 Vectors in the Mouse Airway

Journal of Virology, 2007-11, Vol.81 (22), p.12360-12367

2007

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Emerging gene therapies for cystic fibrosis

Expert review of respiratory medicine, 2019-08, Vol.13 (8), p.709-725

2019

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Identification and Functional Characterization of Cytoplasmic Determinants of Plasmid DNA Nuclear Import

The Journal of biological chemistry, 2009-09, Vol.284 (39), p.26978-26987

2009

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Lung-targeting lentiviral vector for passive immunisation against influenza

Thorax, 2020-12, Vol.75 (12), p.1112-1115

2020

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Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus

Genomic diversity of SARS-CoV-2 in Oxford during United Kingdom’s first national lockdown

Lentiviral and AAV-mediated expression of palivizumab offer protection against Respiratory Syncytial Virus infection

Identification of AAV serotypes for lung gene therapy in human embryonic stem cell-derived lung organoids

A human surfactant B deficiency air-liquid interface cell culture model suitable for gene therapy applications

CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression

Intranasal Lentiviral Vector-Mediated Antibody Delivery Confers Reduction of SARS-CoV-2 Infection in Elderly and Immunocompromised Mice

A Phase I/IIa Safety and Efficacy Study of Nebulized Liposome-mediated Gene Therapy for Cystic Fibrosis Supports a Multidose Trial

Sendai F/HN pseudotyped lentiviral vector transduces human ciliated and non-ciliated airway cells using α 2,3 sialylated receptors

RNA-seq analysis of the human surfactant air-liquid interface culture reveals alveolar type II cell-like transcriptome

Correction of a chronic pulmonary disease through lentiviral vector-mediated protein expression

Lessons learned from lung and liver in-vivo gene therapy: implications for the future

Genome-wide integration site detection using Cas9 enriched amplification-free long-range sequencing

Aerosol delivery of DNA/liposomes to the lung for cystic fibrosis gene therapy

CpG-free plasmid expression cassettes for cystic fibrosis gene therapy

Delivery of genes into the CF airway

Lung directed antibody gene transfer confers protection against SARS-CoV-2 infection

Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis

Progress in Respiratory Gene Therapy

Type I interferon receptor signalling deficiency results in dysregulated innate immune responses to SARS‐CoV‐2 in mice

Pharmacological Characterization of a Novel ENaCα siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis

Lack of Repeat Transduction by Recombinant Adeno-Associated Virus Type 5/5 Vectors in the Mouse Airway

Emerging gene therapies for cystic fibrosis

Identification and Functional Characterization of Cytoplasmic Determinants of Plasmid DNA Nuclear Import

Lung-targeting lentiviral vector for passive immunisation against influenza

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