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Safety, Pharmacokinetics, and Antitumor Activity of AMG 386, a Selective Angiopoietin Inhibitor, in Adult Patients With Advanced Solid Tumors

Journal of clinical oncology, 2009-07, Vol.27 (21), p.3557-3565

2009

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RAGE and Modulation of Ischemic Injury in the Diabetic Myocardium

Diabetes (New York, N.Y.), 2008-07, Vol.57 (7), p.1941-1951

2008

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Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts

Cardiovascular diabetology, 2008-10, Vol.7 (1), p.33-33, Article 33

2008

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Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury

The FASEB journal, 2005-05, Vol.19 (7), p.795-797

2005

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A First-in-Human Study of Conatumumab in Adult Patients with Advanced Solid Tumors

Clinical cancer research, 2010-12, Vol.16 (23), p.5883-5891

2010

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A Phase I, First-in-Human Study of AMG 780, an Angiopoietin-1 and -2 Inhibitor, in Patients with Advanced Solid Tumors

Clinical cancer research, 2016-09, Vol.22 (18), p.4574-4584

2016

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Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore

American journal of physiology. Heart and circulatory physiology, 2009-02, Vol.296 (2), p.H333-H341

2009

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Receptor for advanced-glycation end products : Key modulator of myocardial ischemic injury

Circulation (New York, N.Y.), 2006-03, Vol.113 (9), p.1226-1234

2006

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Safety and Pharmacokinetics of Ganitumab (AMG 479) Combined with Sorafenib, Panitumumab, Erlotinib, or Gemcitabine in Patients with Advanced Solid Tumors

Clinical cancer research, 2012-06, Vol.18 (12), p.3414-3427

2012

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A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors

Oncotarget, 2015-07, Vol.6 (21), p.18693-18706

2015

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Aldose Reductase and AGE-RAGE Pathways: Key Players in Myocardial Ischemic Injury

Annals of the New York Academy of Sciences, 2005-06, Vol.1043 (1), p.702-709

2005

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Central role for aldose reductase pathway in myocardial ischemic injury

The FASEB journal, 2004-08, Vol.18 (11), p.1192-1199

2004

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Aldose reductase activation is a key component of myocardial response to ischemia

The FASEB journal, 2002-02, Vol.16 (2), p.1-22

2002

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Perfusion of hearts with triglyceride-rich particles reproduces the metabolic abnormalities in lipotoxic cardiomyopathy

American journal of physiology: endocrinology and metabolism, 2005-06, Vol.288 (6), p.E1229-E1235

2005

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Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium

The FASEB journal, 2003-12, Vol.17 (15), p.2331-2333

2003

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Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium

The FASEB journal, 2003-12, Vol.17 (15), p.2331-2333

2003

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Protection of ischemic hearts by high glucose is mediated, in part, by GLUT-4

American journal of physiology. Heart and circulatory physiology, 2001-07, Vol.281 (1), p.H290-H297

2001

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Metabolic and functional protection by selective inhibition of nitric oxide synthase 2 during ischemia-reperfusion in isolated perfused hearts

Circulation (New York, N.Y.), 2004-04, Vol.109 (13), p.1668-1673

2004

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Relative importance of enhanced glucose uptake versus attenuation of long-chain acyl carnitines in protecting ischemic myocardium

Coronary artery disease, 2002-09, Vol.13 (6), p.313-318

2002

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A first-in-human study of AMG 780, an angiopoietin-1 and -2 (ANG1/2) inhibitor, in patients (pts) with advanced solid tumors

Journal of clinical oncology, 2014-05, Vol.32 (15_suppl), p.2542-2542

2014

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Clinical activity of AMG 337, an oral MET kinase inhibitor, in adult patients (pts) with MET-amplified gastroesophageal junction (GEJ), gastric (G), or esophageal (E) cancer

Journal of clinical oncology, 2015-01, Vol.33 (3_suppl), p.1-1

2015

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First-in-human study of AMG 337, a highly selective oral inhibitor of MET, in adult patients (pts) with advanced solid tumors

Journal of clinical oncology, 2014-05, Vol.32 (15_suppl), p.2508-2508

2014

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First-in-human study of AMG 208, an oral MET inhibitor, in adult patients (pts) with advanced solid tumors

Journal of clinical oncology, 2013-02, Vol.31 (6_suppl), p.41-41

2013

Volltextzugriff (PDF)

Diels-Alder reaction of 1-azadienes. A total synthesis of deoxynupharidine

Journal of organic chemistry, 1985-07, Vol.50 (15), p.2719-2726

1985

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Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore

American journal of physiology. Heart and circulatory physiology, 2009, Vol.65 (2)

2009

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Safety, Pharmacokinetics, and Antitumor Activity of AMG 386, a Selective Angiopoietin Inhibitor, in Adult Patients With Advanced Solid Tumors

RAGE and Modulation of Ischemic Injury in the Diabetic Myocardium

Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts

Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury

A First-in-Human Study of Conatumumab in Adult Patients with Advanced Solid Tumors

A Phase I, First-in-Human Study of AMG 780, an Angiopoietin-1 and -2 Inhibitor, in Patients with Advanced Solid Tumors

Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore

Receptor for advanced-glycation end products : Key modulator of myocardial ischemic injury

Safety and Pharmacokinetics of Ganitumab (AMG 479) Combined with Sorafenib, Panitumumab, Erlotinib, or Gemcitabine in Patients with Advanced Solid Tumors

A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors

Aldose Reductase and AGE-RAGE Pathways: Key Players in Myocardial Ischemic Injury

Central role for aldose reductase pathway in myocardial ischemic injury

Aldose reductase activation is a key component of myocardial response to ischemia

Perfusion of hearts with triglyceride-rich particles reproduces the metabolic abnormalities in lipotoxic cardiomyopathy

Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium

Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium

Protection of ischemic hearts by high glucose is mediated, in part, by GLUT-4

Metabolic and functional protection by selective inhibition of nitric oxide synthase 2 during ischemia-reperfusion in isolated perfused hearts

Relative importance of enhanced glucose uptake versus attenuation of long-chain acyl carnitines in protecting ischemic myocardium

A first-in-human study of AMG 780, an angiopoietin-1 and -2 (ANG1/2) inhibitor, in patients (pts) with advanced solid tumors

Clinical activity of AMG 337, an oral MET kinase inhibitor, in adult patients (pts) with MET-amplified gastroesophageal junction (GEJ), gastric (G), or esophageal (E) cancer

First-in-human study of AMG 337, a highly selective oral inhibitor of MET, in adult patients (pts) with advanced solid tumors

First-in-human study of AMG 208, an oral MET inhibitor, in adult patients (pts) with advanced solid tumors

Diels-Alder reaction of 1-azadienes. A total synthesis of deoxynupharidine

Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore

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