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Discovery of Vinyl Sulfones as a Novel Class of Neuroprotective Agents toward Parkinson’s Disease Therapy

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1473-1487

2014

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A Novel Pyrazolo[3,4- d ]pyrimidine Induces Heme Oxygenase-1 and Exerts Anti-Inflammatory and Neuroprotective Effects

Molecules and Cells, 2022, 45(3), , pp.134-147

2022

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Vertical grid test and modified horizontal grid test are sensitive methods for evaluating motor dysfunctions in the MPTP mouse model of Parkinson's disease

Brain research, 2010-01, Vol.1306, p.176-183

2010

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Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (32), p.13094-13099

2012

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Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: Novel cytoprotective mechanism against oxidative damage

Pharmacological research, 2008-05, Vol.57 (5), p.325-331

2008

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Ethyl pyruvate rescues nigrostriatal dopaminergic neurons by regulating glial activation in a mouse model of Parkinson's disease

The Journal of immunology (1950), 2011-07, Vol.187 (2), p.960-969

2011

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pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation

The FASEB journal, 2007-01, Vol.21 (1), p.179-187

2007

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Matrix Metalloproteinase-3 Is Increased and Participates in Neuronal Apoptotic Signaling Downstream of Caspase-12 during Endoplasmic Reticulum Stress

The Journal of biological chemistry, 2010-05, Vol.285 (22), p.16444-16452

2010

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Protective effect of sulforaphane against dopaminergic cell death

The Journal of pharmacology and experimental therapeutics, 2007-04, Vol.321 (1), p.249

2007

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Immobilization stress causes increases in tetrahydrobiopterin, dopamine, and neuromelanin and oxidative damage in the nigrostriatal system

Journal of neurochemistry, 2005-10, Vol.95 (1), p.89-98

2005

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Okadaic acid increases autophagosomes in rat neurons: Implications for Alzheimer's disease

Journal of neuroscience research, 2008-11, Vol.86 (14), p.3230-3239

2008

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Enhanced efficacy of human brain-derived neural stem cells by transplantation of cell aggregates in a rat model of Parkinson's disease

대한신경외과학회지, 2014, 56(5), , pp.383-389

2014

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Dopamine‐dependent cytotoxicity of tetrahydrobiopterin: a possible mechanism for selective neurodegeneration in Parkinson's disease

Journal of neurochemistry, 2003-07, Vol.86 (1), p.143-152

2003

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Up-Regulation of Tryptophan Hydroxylase Expression and Serotonin Synthesis by Sertraline

Molecular pharmacology, 2002-04, Vol.61 (4), p.778-785

2002

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Cytosolic labile zinc accumulation in degenerating dopaminergic neurons of mouse brain after MPTP treatment

Brain research, 2009-08, Vol.1286, p.208-214

2009

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Particular vulnerability of rat mesencephalic dopaminergic neurons to tetrahydrobiopterin: Relevance to Parkinson’s disease

Neurobiology of disease, 2007-01, Vol.25 (1), p.112-120

2007

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Matrix metalloproteinase-3 contributes to vulnerability of the nigral dopaminergic neurons

Neurochemistry international, 2010, Vol.56 (1), p.161-167

2010

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Pyruvate Prevents Dopaminergic Neurodegeneration and Motor Deficits in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Model of Parkinson’s Disease

Molecular neurobiology, 2022-11, Vol.59 (11), p.6956-6970

2022

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Impact of Circadian Nuclear Receptor REV-ERBα on Midbrain Dopamine Production and Mood Regulation

Cell, 2014-05, Vol.157 (4), p.858-868

2014

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Are human dental papilla-derived stem cell and human brain-derived neural stem cell transplantations suitable for treatment of Parkinson's disease?

Neural regeneration research, 2013-05, Vol.8 (13), p.1190-1200

2013

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Role of matrix metalloproteinase-3 in neurodegeneration

Journal of neurochemistry, 2011, Vol.116 (1), p.22-32

2011

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Increases in TH immunoreactivity, neuromelanin and degeneration in the substantia nigra of middle aged mice

Neuroscience letters, 2006-04, Vol.396 (3), p.263-268

2006

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KMS99220 Exerts Anti-Inflammatory Effects, Activates the Nrf2 Signaling and Interferes with IKK, JNK and p38 MAPK via HO-1

Molecules and Cells, 2019, 42(10), , pp.702-710

2019

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A novel pyrazolo [3,4-d] pyrimidine, KKC080106, activates the Nrf2 pathway and protects nigral dopaminergic neurons

Experimental neurology, 2020-10, Vol.332, p.113387, Article 113387

2020

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KMS99220 Exerts Anti-Inflammatory Effects, Activates the Nrf2 Signaling and Interferes with IKK, JNK and p38 MAPK via HO-1

Molecules and cells, 2019, Vol.42 (10), p.702-710

2019

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Discovery of Vinyl Sulfones as a Novel Class of Neuroprotective Agents toward Parkinson’s Disease Therapy

A Novel Pyrazolo[3,4- d ]pyrimidine Induces Heme Oxygenase-1 and Exerts Anti-Inflammatory and Neuroprotective Effects

Vertical grid test and modified horizontal grid test are sensitive methods for evaluating motor dysfunctions in the MPTP mouse model of Parkinson's disease

Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise

Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: Novel cytoprotective mechanism against oxidative damage

Ethyl pyruvate rescues nigrostriatal dopaminergic neurons by regulating glial activation in a mouse model of Parkinson's disease

pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation

Matrix Metalloproteinase-3 Is Increased and Participates in Neuronal Apoptotic Signaling Downstream of Caspase-12 during Endoplasmic Reticulum Stress

Protective effect of sulforaphane against dopaminergic cell death

Immobilization stress causes increases in tetrahydrobiopterin, dopamine, and neuromelanin and oxidative damage in the nigrostriatal system

Okadaic acid increases autophagosomes in rat neurons: Implications for Alzheimer's disease

Enhanced efficacy of human brain-derived neural stem cells by transplantation of cell aggregates in a rat model of Parkinson's disease

Dopamine‐dependent cytotoxicity of tetrahydrobiopterin: a possible mechanism for selective neurodegeneration in Parkinson's disease

Up-Regulation of Tryptophan Hydroxylase Expression and Serotonin Synthesis by Sertraline

Cytosolic labile zinc accumulation in degenerating dopaminergic neurons of mouse brain after MPTP treatment

Particular vulnerability of rat mesencephalic dopaminergic neurons to tetrahydrobiopterin: Relevance to Parkinson’s disease

Matrix metalloproteinase-3 contributes to vulnerability of the nigral dopaminergic neurons

Pyruvate Prevents Dopaminergic Neurodegeneration and Motor Deficits in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Model of Parkinson’s Disease

Impact of Circadian Nuclear Receptor REV-ERBα on Midbrain Dopamine Production and Mood Regulation

Are human dental papilla-derived stem cell and human brain-derived neural stem cell transplantations suitable for treatment of Parkinson's disease?

Role of matrix metalloproteinase-3 in neurodegeneration

Increases in TH immunoreactivity, neuromelanin and degeneration in the substantia nigra of middle aged mice

KMS99220 Exerts Anti-Inflammatory Effects, Activates the Nrf2 Signaling and Interferes with IKK, JNK and p38 MAPK via HO-1

A novel pyrazolo [3,4-d] pyrimidine, KKC080106, activates the Nrf2 pathway and protects nigral dopaminergic neurons

KMS99220 Exerts Anti-Inflammatory Effects, Activates the Nrf2 Signaling and Interferes with IKK, JNK and p38 MAPK via HO-1

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