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Effect of Chemical Permeation Enhancers on Stratum Corneum Barrier Lipid Organizational Structure and Interferon Alpha Permeability

Molecular pharmaceutics, 2013-06, Vol.10 (6), p.2248-2260

2013

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Drug delivery through the skin: molecular simulations of barrier lipids to design more effective noninvasive dermal and transdermal delivery systems for small molecules, biologics, and cosmetics

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 2011-09, Vol.3 (5), p.449-462

2011

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Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: Towards non-invasive glaucoma gene therapy

Nanomedicine, 2014-11, Vol.10 (8), p.1637-1647

2014

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Pharmaceutical characterization of solid and dispersed carbon nanotubes as nanoexcipients

International journal of nanomedicine, 2012-01, Vol.7 (default), p.403-415

2012

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Conformational Analysis of the Carboxy-Terminal Tails of Human β-Tubulin Isotypes

Biophysical journal, 2008-03, Vol.94 (6), p.1971-1982

2008

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Comparative modelling of human β tubulin isotypes and implications for drug binding

Nanotechnology, 2006-02, Vol.17 (4), p.S90-S100

2006

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The Roles of β-Tubulin Mutations and Isotype Expression in Acquired Drug Resistance

Cancer Informatics, 2007-01, Vol.3, p.159-181

2007

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Characterization of an inhibitory dynamic pharmacophore for the ERCC1–XPA interaction using a combined molecular dynamics and virtual screening approach

Journal of molecular graphics & modelling, 2009-09, Vol.28 (2), p.113-130

2009

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Challenges in neuroprotective nanomedicine development: progress towards noninvasive gene therapy of glaucoma

Nanomedicine (London, England), 2012-07, Vol.7 (7), p.1067-1083

2012

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Probabilistic analysis of the frequencies of amino acid pairs within characterized protein sequences

Physica A, 2006-10, Vol.370 (2), p.651-662

2006

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A Unique Mode of Microtubule Stabilization Induced by Peloruside A

Journal of molecular biology, 2008-05, Vol.378 (5), p.1016-1030

2008

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Direct Catalysis of Lysine 48-linked Polyubiquitin Chains by the Ubiquitin-activating Enzyme

The Journal of biological chemistry, 2007-12, Vol.282 (52), p.37454-37460

2007

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Identification and Characterization of an Intermediate Taxol Binding Site Within Microtubule Nanopores and a Mechanism for Tubulin Isotype Binding Selectivity

Journal of Chemical Information and Modeling, 2009-02, Vol.49 (2), p.424-436

2009

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A Computational Model for Overcoming Drug Resistance Using Selective Dual-Inhibitors for Aurora Kinase A and Its T217D Variant

Molecular pharmaceutics, 2013-12, Vol.10 (12), p.4572-4589

2013

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Free Energy Calculations on the Binding of Colchicine and Its Derivatives with the α/β-Tubulin Isoforms

Journal of Chemical Information and Modeling, 2008-09, Vol.48 (9), p.1824-1832

2008

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Microtubule Assembly of Isotypically Purified Tubulin and Its Mixtures

Biophysical journal, 2008-08, Vol.95 (4), p.1993-2008

2008

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Interactions of laulimalide, peloruside, and their derivatives with the isoforms of β-tubulin

Canadian journal of chemistry, 2013-07, Vol.91 (7), p.511-517

2013

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Tubulin electrostatics and isotype specific drug binding

Canadian journal of physics, 2008-04, Vol.86 (4), p.635-640

2008

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Computer assisted design of second-generation colchicine derivatives

Interdisciplinary sciences : computational life sciences, 2010-06, Vol.2 (2), p.169-174

2010

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Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing

Journal of molecular graphics & modelling, 2008-11, Vol.27 (4), p.497-505

2008

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Homology modeling of tubulin: influence predictions for microtubule's biophysical properties

European biophysics journal, 2006-12, Vol.36 (1), p.35-43

2006

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Discovery and Characterization of the Laulimalide-Microtubule Binding Mode by Mass Shift Perturbation Mapping

Chemistry & biology, 2010-07, Vol.17 (7), p.725-734

2010

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Creation of a Pluripotent Ubiquitin-Conjugating Enzyme

Molecular and Cellular Biology, 2001-10, Vol.21 (19), p.6537-6548

2001

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The evolution of the structure of tubulin and its potential consequences for the role and function of microtubules in cells and embryos

The International journal of developmental biology, 2006, Vol.50 (2-3), p.341-358

2006

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Free Energy Calculations on the Binding of Colchicine and Its Derivatives with the [alpha]/[beta]-Tubulin Isoforms

Journal of chemical information and modeling, 2008-09, Vol.48 (9), p.1824

2008

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Effect of Chemical Permeation Enhancers on Stratum Corneum Barrier Lipid Organizational Structure and Interferon Alpha Permeability

Drug delivery through the skin: molecular simulations of barrier lipids to design more effective noninvasive dermal and transdermal delivery systems for small molecules, biologics, and cosmetics

Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: Towards non-invasive glaucoma gene therapy

Pharmaceutical characterization of solid and dispersed carbon nanotubes as nanoexcipients

Conformational Analysis of the Carboxy-Terminal Tails of Human β-Tubulin Isotypes

Comparative modelling of human β tubulin isotypes and implications for drug binding

The Roles of β-Tubulin Mutations and Isotype Expression in Acquired Drug Resistance

Characterization of an inhibitory dynamic pharmacophore for the ERCC1–XPA interaction using a combined molecular dynamics and virtual screening approach

Challenges in neuroprotective nanomedicine development: progress towards noninvasive gene therapy of glaucoma

Probabilistic analysis of the frequencies of amino acid pairs within characterized protein sequences

A Unique Mode of Microtubule Stabilization Induced by Peloruside A

Direct Catalysis of Lysine 48-linked Polyubiquitin Chains by the Ubiquitin-activating Enzyme

Identification and Characterization of an Intermediate Taxol Binding Site Within Microtubule Nanopores and a Mechanism for Tubulin Isotype Binding Selectivity

A Computational Model for Overcoming Drug Resistance Using Selective Dual-Inhibitors for Aurora Kinase A and Its T217D Variant

Free Energy Calculations on the Binding of Colchicine and Its Derivatives with the α/β-Tubulin Isoforms

Microtubule Assembly of Isotypically Purified Tubulin and Its Mixtures

Interactions of laulimalide, peloruside, and their derivatives with the isoforms of β-tubulin

Tubulin electrostatics and isotype specific drug binding

Computer assisted design of second-generation colchicine derivatives

Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing

Homology modeling of tubulin: influence predictions for microtubule's biophysical properties

Discovery and Characterization of the Laulimalide-Microtubule Binding Mode by Mass Shift Perturbation Mapping

Creation of a Pluripotent Ubiquitin-Conjugating Enzyme

The evolution of the structure of tubulin and its potential consequences for the role and function of microtubules in cells and embryos

Free Energy Calculations on the Binding of Colchicine and Its Derivatives with the [alpha]/[beta]-Tubulin Isoforms

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