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Preclinical efficacy and safety of KCNH2-G628S gene therapy for postoperative atrial fibrillation

The Journal of thoracic and cardiovascular surgery, 2017-11, Vol.154 (5), p.1644-1651.e8

2017

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Antibodies Contribute to Effective Vaccination against Respiratory Infection by Type A Francisella tularensis Strains

Infection and Immunity, 2011-04, Vol.79 (4), p.1770-1778

2011

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Expression of either Lethal Toxin or Edema Toxin by Bacillus anthracis Is Sufficient for Virulence in a Rabbit Model of Inhalational Anthrax

Infection and Immunity, 2012-07, Vol.80 (7), p.2414-2425

2012

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Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection

PloS one, 2015-07, Vol.10 (7), p.e0130952

2015

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Identification of an Attenuated Substrain of Francisella tularensis SCHU S4 by Phenotypic and Genotypic Analyses

Pathogens (Basel), 2021-05, Vol.10 (6), p.638

2021

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Safety and biodistribution assessment of sc-rAAV2.5IL-1Ra administered via intra-articular injection in a mono-iodoacetate-induced osteoarthritis rat model

Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.15052, Article 15052

2016

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Intranasal Vaccination Induces Protective Immunity against Intranasal Infection with Virulent Francisella tularensis Biovar A

Infection and Immunity, 2005-05, Vol.73 (5), p.2644-2654

2005

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Aberrant promoter hypermethylation of the Death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens

Cancer research (Chicago, Ill.), 2004-06, Vol.64 (11), p.3844-3848

2004

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Life-span inhalation exposure to mainstream cigarette smoke induces lung cancer in B6C3F1 mice through genetic and epigenetic pathways

Carcinogenesis (New York), 2005-11, Vol.26 (11), p.1999-2009

2005

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The Natural History of Pneumonic Tularemia in Female Fischer 344 Rats after Inhalational Exposure to Aerosolized Francisella tularensis Subspecies tularensis Strain SCHU S4

The American journal of pathology, 2017-02, Vol.187 (2), p.252-267

2017

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Gene Promoter Hypermethylation in Mouse Lung Tumors

Molecular cancer research, 2006-04, Vol.4 (4), p.267-273

2006

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Scientific and Regulatory Policy Committee Points to Consider: Nonclinical Research and Development of In Vivo Gene Therapy Products, Emphasizing Adeno-Associated Virus Vectors

Toxicologic pathology, 2022-01, Vol.50 (1), p.118-146

2022

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Preclinical safety and biodistribution assessment of Ad‐KCNH2‐G628S administered via atrial painting in New Zealand white rabbits

Basic & clinical pharmacology & toxicology, 2023-08, Vol.133 (2), p.179-193

2023

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Cigarette smoke suppresses Th1 cytokine production and increases RSV expression in a neonatal model

American journal of physiology. Lung cellular and molecular physiology, 2006-02, Vol.290 (2), p.L222-L231

2006

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Lethal Factor, but Not Edema Factor, Is Required to Cause Fatal Anthrax in Cynomolgus Macaques after Pulmonary Spore Challenge

The American journal of pathology, 2014-12, Vol.184 (12), p.3205-3216

2014

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Chromatin remodeling by the histone methyltransferase EZH2 drives lung pre-malignancy and is a target for cancer prevention

Clinical epigenetics, 2021-02, Vol.13 (1), p.44, Article 44

2021

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Preclinical efficacy and safety of KCNH2-G628S gene therapy for post-operative atrial fibrillation

The Journal of thoracic and cardiovascular surgery, 2017-05, Vol.154 (5), p.1644-1651.e8

2017

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Preclinical evaluation of a recombinant adeno-associated virus vector expressing human alpha-1 antitrypsin made using a recombinant herpes simplex virus production method

Human gene therapy, 2011-02, Vol.22 (2), p.155

2011

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The SARS-CoV ferret model in an infection–challenge study

Virology (New York, N.Y.), 2008-04, Vol.374 (1), p.151-163

2008

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A Review of the Histopathology of Cigarette Smoke–Induced Lung Cancer in Rats and Mice

International journal of toxicology, 2007-07, Vol.26 (4), p.307-313

2007

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Intrapleural administration of an AAVrh.10 vector coding for human α1-antitrypsin for the treatment of α1-antitrypsin deficiency

Human gene therapy. Clinical development, 2013-12, Vol.24 (4), p.161

2013

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Vaccination of Fischer 344 rats against pulmonary infections by Francisella tularensis type A strains

Vaccine, 2009-07, Vol.27 (34), p.4684-4693

2009

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C-Reactive Protein-Mediated Suppression of Nephrotoxic Nephritis: Role of Macrophages, Complement, and Fcγ Receptors

Journal of Immunology, 2007-01, Vol.178 (1), p.530-538

2007

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Cowpox virus inhibits human dendritic cell immune function by nonlethal, nonproductive infection

Virology (New York, N.Y.), 2011-04, Vol.412 (2), p.411-425

2011

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Granuloma Formation Induced by Low-Dose Chronic Silica Inhalation is Associated with an Anti-Apoptotic Response in Lewis Rats

Journal of Toxicology and Environmental Health, Part A, 2010-01, Vol.73 (10), p.669-683

2010

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Preclinical efficacy and safety of KCNH2-G628S gene therapy for postoperative atrial fibrillation

Antibodies Contribute to Effective Vaccination against Respiratory Infection by Type A Francisella tularensis Strains

Expression of either Lethal Toxin or Edema Toxin by Bacillus anthracis Is Sufficient for Virulence in a Rabbit Model of Inhalational Anthrax

Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection

Identification of an Attenuated Substrain of Francisella tularensis SCHU S4 by Phenotypic and Genotypic Analyses

Safety and biodistribution assessment of sc-rAAV2.5IL-1Ra administered via intra-articular injection in a mono-iodoacetate-induced osteoarthritis rat model

Intranasal Vaccination Induces Protective Immunity against Intranasal Infection with Virulent Francisella tularensis Biovar A

Aberrant promoter hypermethylation of the Death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens

Life-span inhalation exposure to mainstream cigarette smoke induces lung cancer in B6C3F1 mice through genetic and epigenetic pathways

The Natural History of Pneumonic Tularemia in Female Fischer 344 Rats after Inhalational Exposure to Aerosolized Francisella tularensis Subspecies tularensis Strain SCHU S4

Gene Promoter Hypermethylation in Mouse Lung Tumors

Scientific and Regulatory Policy Committee Points to Consider: Nonclinical Research and Development of In Vivo Gene Therapy Products, Emphasizing Adeno-Associated Virus Vectors

Preclinical safety and biodistribution assessment of Ad‐KCNH2‐G628S administered via atrial painting in New Zealand white rabbits

Cigarette smoke suppresses Th1 cytokine production and increases RSV expression in a neonatal model

Lethal Factor, but Not Edema Factor, Is Required to Cause Fatal Anthrax in Cynomolgus Macaques after Pulmonary Spore Challenge

Chromatin remodeling by the histone methyltransferase EZH2 drives lung pre-malignancy and is a target for cancer prevention

Preclinical efficacy and safety of KCNH2-G628S gene therapy for post-operative atrial fibrillation

Preclinical evaluation of a recombinant adeno-associated virus vector expressing human alpha-1 antitrypsin made using a recombinant herpes simplex virus production method

The SARS-CoV ferret model in an infection–challenge study

A Review of the Histopathology of Cigarette Smoke–Induced Lung Cancer in Rats and Mice

Intrapleural administration of an AAVrh.10 vector coding for human α1-antitrypsin for the treatment of α1-antitrypsin deficiency

Vaccination of Fischer 344 rats against pulmonary infections by Francisella tularensis type A strains

C-Reactive Protein-Mediated Suppression of Nephrotoxic Nephritis: Role of Macrophages, Complement, and Fcγ Receptors

Cowpox virus inhibits human dendritic cell immune function by nonlethal, nonproductive infection

Granuloma Formation Induced by Low-Dose Chronic Silica Inhalation is Associated with an Anti-Apoptotic Response in Lewis Rats

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