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Inhibition of Colony-Stimulating-Factor-1 Signaling in vivo with the Orally Bioavailable cFMS Kinase Inhibitor GW2580

Proceedings of the National Academy of Sciences - PNAS, 2005-11, Vol.102 (44), p.16078-16083

2005

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Engineering a “muco‐trapping” ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19

Bioengineering & translational medicine, 2024-07, Vol.9 (4), p.e10650-n/a

2024

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Pharmacokinetics and Safety of FV-100, a Novel Oral Anti-Herpes Zoster Nucleoside Analogue, Administered in Single and Multiple Doses to Healthy Young Adult and Elderly Adult Volunteers

Antimicrobial Agents and Chemotherapy, 2011-06, Vol.55 (6), p.2847-2854

2011

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Characterization of a Protective Monoclonal Antibody Recognizing Staphylococcus aureus MSCRAMM Protein Clumping Factor A

Infection and Immunity, 2003-12, Vol.71 (12), p.6864-6870

2003

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Automated sample preparation facilitated by PhyNexus MEA purification system for oligosaccharide mapping of glycoproteins

Analytical biochemistry, 2007-10, Vol.369 (2), p.202-209

2007

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Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats

The Journal of pharmacology and experimental therapeutics, 2008-07, Vol.326 (1), p.41-50

2008

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Phosphatidylserine-targeting antibodies augment the anti-tumorigenic activity of anti-PD-1 therapy by enhancing immune activation and downregulating pro-oncogenic factors induced by T-cell checkpoint inhibition in murine triple-negative breast cancers

Breast cancer research : BCR, 2016-05, Vol.18 (1), p.50-50, Article 50

2016

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Characterization of a Humanized Monoclonal Antibody Recognizing Clumping Factor A Expressed by Staphylococcus aureus

Infection and Immunity, 2005-08, Vol.73 (8), p.5229-5232

2005

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Monoclonal antibodies specific for Candida albicans Als3 that immunolabel fungal cells in vitro and in vivo and block adhesion to host surfaces

Journal of microbiological methods, 2009-07, Vol.78 (1), p.71-78

2009

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Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma

Cancer immunology research, 2016-06, Vol.4 (6), p.531-540

2016

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Production of monoclonal antibodies using recombinant baculovirus displaying gp64–fusion proteins

Journal of immunological methods, 2000-02, Vol.234 (1), p.123-135

2000

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Site-specific Conjugation on Serine → Cysteine Variant Monoclonal Antibodies

The Journal of biological chemistry, 2000-09, Vol.275 (39), p.30445-30450

2000

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Monoclonal antibodies recognizing the Enterococcus faecalis collagen-binding MSCRAMM Ace: Conditional expression and binding analysis

Microbial pathogenesis, 2007-08, Vol.43 (2), p.55-66

2007

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Abstract 604: PTX-35, a potential first-in-class TNFRSF25 agonist, reduced the suppressive activity of regulatory T cells and enhanced CD4+ T cell effector responses, in the presence of tumor antigens, in a murine melanoma model

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.604-604

2021

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Abstract 3652: Combinational activity of LAG3 and PD-1 targeted therapies is significantly enhanced by the addition of phosphatidylserine targeting antibodies and establishes an anti-tumor memory response in murine triple negative breast cancer

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3652-3652

2017

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Abstract 3657: Phosphatidylserine-targeting antibodies enhance anti-tumor activity of a tumor vaccine in a HPV-induced tumor model

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3657-3657

2017

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Abstract 1651: Targeting phosphatidylserine in combination with adoptive T cell transfer eliminates advanced tumors without off-target toxicities in a melanoma preclinical model

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1651-1651

2017

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Abstract 5116: Phosphatidylserine-targeting antibodies augment anti-tumor activity of PD-1 antibodies and alter immuno-profiles in murine triple negative breast cancers

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.5116-5116

2016

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Effects of pCIneo and pCEP4 expression vectors on transient and stable protein production in human and simian cell lines

Cytotechnology (Dordrecht), 2001-05, Vol.35 (3), p.181-187

2001

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Improved Biodistribution, Tumor Targeting, and Reduced Immunogenicity in Mice with a γ4 Variant of Campath-1H

Proceedings of the National Academy of Sciences - PNAS, 1995-12, Vol.92 (26), p.11980-11984

1995

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A panel of monoclonal antibodies recognizing the Staphylococcus epidermidis fibrinogen-binding MSCRAMM SdrG

Hybridoma (2005), 2007-02, Vol.26 (1), p.28-34

2007

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Optimization of transient gene expression in mammalian cells and potential for scale-up using flow electroporation

Cytotechnology (Dordrecht), 1998-11, Vol.28 (1-3), p.147-155

1998

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DMPK and Metabolism Studies of Nucleoside Phosphoramidates Including INX-08189, A Novel Double Pro-drug and Clinical Candidate for Hepatitis C Virus Therapy

Antiviral research, 2011-05, Vol.90 (2), p.A22-A23

2011

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Novel gene sequences expressed by human melanoma cells identified by molecular subtraction

Cancer research (Chicago, Ill.), 1991-03, Vol.51 (5), p.1418-1425

1991

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Distribution of mono-, di-, and tri-O-acetylated sialic acids in normal and neoplastic colon

Cancer research (Chicago, Ill.), 1988-01, Vol.48 (2), p.483-489

1988

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Inhibition of Colony-Stimulating-Factor-1 Signaling in vivo with the Orally Bioavailable cFMS Kinase Inhibitor GW2580

Engineering a “muco‐trapping” ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19

Pharmacokinetics and Safety of FV-100, a Novel Oral Anti-Herpes Zoster Nucleoside Analogue, Administered in Single and Multiple Doses to Healthy Young Adult and Elderly Adult Volunteers

Characterization of a Protective Monoclonal Antibody Recognizing Staphylococcus aureus MSCRAMM Protein Clumping Factor A

Automated sample preparation facilitated by PhyNexus MEA purification system for oligosaccharide mapping of glycoproteins

Effects of the cFMS kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580) in normal and arthritic rats

Phosphatidylserine-targeting antibodies augment the anti-tumorigenic activity of anti-PD-1 therapy by enhancing immune activation and downregulating pro-oncogenic factors induced by T-cell checkpoint inhibition in murine triple-negative breast cancers

Characterization of a Humanized Monoclonal Antibody Recognizing Clumping Factor A Expressed by Staphylococcus aureus

Monoclonal antibodies specific for Candida albicans Als3 that immunolabel fungal cells in vitro and in vivo and block adhesion to host surfaces

Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma

Production of monoclonal antibodies using recombinant baculovirus displaying gp64–fusion proteins

Site-specific Conjugation on Serine → Cysteine Variant Monoclonal Antibodies

Monoclonal antibodies recognizing the Enterococcus faecalis collagen-binding MSCRAMM Ace: Conditional expression and binding analysis

Abstract 604: PTX-35, a potential first-in-class TNFRSF25 agonist, reduced the suppressive activity of regulatory T cells and enhanced CD4+ T cell effector responses, in the presence of tumor antigens, in a murine melanoma model

Abstract 3652: Combinational activity of LAG3 and PD-1 targeted therapies is significantly enhanced by the addition of phosphatidylserine targeting antibodies and establishes an anti-tumor memory response in murine triple negative breast cancer

Abstract 3657: Phosphatidylserine-targeting antibodies enhance anti-tumor activity of a tumor vaccine in a HPV-induced tumor model

Abstract 1651: Targeting phosphatidylserine in combination with adoptive T cell transfer eliminates advanced tumors without off-target toxicities in a melanoma preclinical model

Abstract 5116: Phosphatidylserine-targeting antibodies augment anti-tumor activity of PD-1 antibodies and alter immuno-profiles in murine triple negative breast cancers

Effects of pCIneo and pCEP4 expression vectors on transient and stable protein production in human and simian cell lines

Improved Biodistribution, Tumor Targeting, and Reduced Immunogenicity in Mice with a γ4 Variant of Campath-1H

A panel of monoclonal antibodies recognizing the Staphylococcus epidermidis fibrinogen-binding MSCRAMM SdrG

Optimization of transient gene expression in mammalian cells and potential for scale-up using flow electroporation

DMPK and Metabolism Studies of Nucleoside Phosphoramidates Including INX-08189, A Novel Double Pro-drug and Clinical Candidate for Hepatitis C Virus Therapy

Novel gene sequences expressed by human melanoma cells identified by molecular subtraction

Distribution of mono-, di-, and tri-O-acetylated sialic acids in normal and neoplastic colon

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