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A Lipid Pathway for Ligand Binding Is Necessary for a Cannabinoid G Protein-coupled Receptor

The Journal of biological chemistry, 2010-06, Vol.285 (23), p.17954-17964

2010

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Towards A Molecular Understanding of The Cannabinoid Related Orphan Receptor GPR18: A Focus on Its Constitutive Activity

International journal of molecular sciences, 2019-05, Vol.20 (9), p.2300

2019

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Identification of Crucial Amino Acid Residues Involved in Agonist Signaling at the GPR55 Receptor

Biochemistry (Easton), 2017-01, Vol.56 (3), p.473-486

2017

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A Closer Look at Anandamide Interaction With TRPV1

Frontiers in molecular biosciences, 2020-07, Vol.7, p.144-144

2020

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GPR6 Structural Insights: Homology Model Construction and Docking Studies

Molecules (Basel, Switzerland), 2020-02, Vol.25 (3), p.725

2020

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Endogenous lipid activated G protein-coupled receptors: Emerging structural features from crystallography and molecular dynamics simulations

Chemistry and physics of lipids, 2013-04, Vol.169, p.46-56

2013

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Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593

Frontiers in pharmacology, 2022-10, Vol.13, p.919605-919605

2022

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Identification of the GPR55 Antagonist Binding Site Using a Novel Set of High-Potency GPR55 Selective Ligands

Biochemistry (Easton), 2013-12, Vol.52 (52), p.9456-9469

2013

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Identification of the GPR55 Agonist Binding Site Using a Novel Set of High-Potency GPR55 Selective Ligands

Biochemistry (Easton), 2011-06, Vol.50 (25), p.5633-5647

2011

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Design, synthesis and biological evaluation of GPR55 agonists

Bioorganic & medicinal chemistry, 2017-08, Vol.25 (16), p.4355-4367

2017

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Molecular Targets of the Phytocannabinoids: A Complex Picture

Phytocannabinoids, 2017, Vol.103, p.103-131

2017

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An Aromatic Microdomain at the Cannabinoid CB1 Receptor Constitutes an Agonist/Inverse Agonist Binding Region

Journal of medicinal chemistry, 2003-11, Vol.46 (24), p.5139-5152

2003

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A dual substrate kinetic model for cytochrome P450BM3-F87G catalysis: simultaneous binding of long chain aldehydes and 4-fluorophenol

Biotechnology letters, 2017-02, Vol.39 (2), p.311-321

2017

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Therapeutic Exploitation of GPR18: Beyond the Cannabinoids?: Miniperspective

Journal of medicinal chemistry, 2020-12, Vol.63 (23), p.14216-14227

2020

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Mutation Studies of Ser7.39 and Ser2.60 in the Human CB1 Cannabinoid Receptor: Evidence for a Serine-Induced Bend in CB1 Transmembrane Helix 7

Molecular pharmacology, 2007-06, Vol.71 (6), p.1512-1524

2007

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Therapeutic Exploitation of GPR18: Beyond the Cannabinoids?

Journal of medicinal chemistry, 2020-12, Vol.63 (23), p.14216-14227

2020

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N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) Interaction with LYS 3.28(192) Is Crucial for Its Inverse Agonism at the Cannabinoid CB1 Receptor

Molecular pharmacology, 2002-12, Vol.62 (6), p.1274-1287

2002

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The Nucleotide-Free State of the Cannabinoid CB2/Gi Complex

Cell, 2020-02, Vol.180 (4), p.603-604

2020

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Methods for the Development of In Silico GPCR Models

Methods in enzymology, 2017, Vol.593, p.405-448

2017

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TRPV1 Activation by Anandamide via a Unique Lipid Pathway

Journal of chemical information and modeling, 2021-12, Vol.61 (12), p.5742-5746

2021

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Pregnenolone Can Protect the Brain from Cannabis Intoxication

Science (American Association for the Advancement of Science), 2014-01, Vol.343 (6166), p.94-98

2014

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Helix 8 Leu in the CB1 Cannabinoid Receptor Contributes to Selective Signal Transduction Mechanisms

The Journal of biological chemistry, 2007-08, Vol.282 (34), p.25100-25113

2007

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Discovery of a Biased Allosteric Modulator for Cannabinoid 1 Receptor: Preclinical Anti-Glaucoma Efficacy

Journal of medicinal chemistry, 2021-06, Vol.64 (12), p.8104-8126

2021

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Design, synthesis, and evaluation of substituted alkylindoles that activate G protein-coupled receptors distinct from the cannabinoid CB1 and CB2 receptors

European journal of medicinal chemistry, 2023-03, Vol.249, p.115123-115123, Article 115123

2023

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A Lipid Pathway for Ligand Binding Is Necessary for a Cannabinoid G Protein-coupled Receptor

Towards A Molecular Understanding of The Cannabinoid Related Orphan Receptor GPR18: A Focus on Its Constitutive Activity

Identification of Crucial Amino Acid Residues Involved in Agonist Signaling at the GPR55 Receptor

A Closer Look at Anandamide Interaction With TRPV1

GPR6 Structural Insights: Homology Model Construction and Docking Studies

Endogenous lipid activated G protein-coupled receptors: Emerging structural features from crystallography and molecular dynamics simulations

Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593

Identification of the GPR55 Antagonist Binding Site Using a Novel Set of High-Potency GPR55 Selective Ligands

Identification of the GPR55 Agonist Binding Site Using a Novel Set of High-Potency GPR55 Selective Ligands

Design, synthesis and biological evaluation of GPR55 agonists

Molecular Targets of the Phytocannabinoids: A Complex Picture

An Aromatic Microdomain at the Cannabinoid CB1 Receptor Constitutes an Agonist/Inverse Agonist Binding Region

A dual substrate kinetic model for cytochrome P450BM3-F87G catalysis: simultaneous binding of long chain aldehydes and 4-fluorophenol

Therapeutic Exploitation of GPR18: Beyond the Cannabinoids?: Miniperspective

Mutation Studies of Ser7.39 and Ser2.60 in the Human CB1 Cannabinoid Receptor: Evidence for a Serine-Induced Bend in CB1 Transmembrane Helix 7

Therapeutic Exploitation of GPR18: Beyond the Cannabinoids?

N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) Interaction with LYS 3.28(192) Is Crucial for Its Inverse Agonism at the Cannabinoid CB1 Receptor

The Nucleotide-Free State of the Cannabinoid CB2/Gi Complex

Methods for the Development of In Silico GPCR Models

TRPV1 Activation by Anandamide via a Unique Lipid Pathway

Pregnenolone Can Protect the Brain from Cannabis Intoxication

Helix 8 Leu in the CB1 Cannabinoid Receptor Contributes to Selective Signal Transduction Mechanisms

Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2‑Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators

Discovery of a Biased Allosteric Modulator for Cannabinoid 1 Receptor: Preclinical Anti-Glaucoma Efficacy

Design, synthesis, and evaluation of substituted alkylindoles that activate G protein-coupled receptors distinct from the cannabinoid CB1 and CB2 receptors

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