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Effects of GBT1118, a voxelotor analog, on bone disease in sickle cell disease mice

Scientific reports, 2024-09, Vol.14 (1), p.22330-14, Article 22330

2024

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Inhibition of FGFR Signaling Partially Rescues Osteoarthritis in Mice Overexpressing High Molecular Weight FGF2 Isoforms

Endocrinology (Philadelphia), 2020-01, Vol.161 (1), p.1

2020

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Fibroblast growth factor-2, bone homeostasis and fracture repair

Current pharmaceutical design, 2013, Vol.19 (19), p.3354-3363

2013

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Gait disturbances and muscle dysfunction in fibroblast growth factor 2 knockout mice

Scientific reports, 2021-05, Vol.11 (1), p.11005-12, Article 11005

2021

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Ablation of low‐molecular‐weight FGF2 isoform accelerates murine osteoarthritis while loss of high‐molecular‐weight FGF2 isoforms offers protection

Journal of cellular physiology, 2019-04, Vol.234 (4), p.4418-4431

2019

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FGF receptor inhibitor BGJ398 partially rescues osteoarthritis-like phenotype in older high molecular weight FGF2 transgenic mice via multiple mechanisms

Scientific reports, 2022-09, Vol.12 (1), p.15968-15968, Article 15968

2022

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Role of fibroblast growth factor 2 and wnt signaling in anabolic effects of parathyroid hormone on bone formation

Journal of cellular physiology, 2012-11, Vol.227 (11), p.3539-3545

2012

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Fibroblast Growth Factor 2 Stimulation of Osteoblast Differentiation and Bone Formation Is Mediated by Modulation of the Wnt Signaling Pathway

The Journal of biological chemistry, 2011-11, Vol.286 (47), p.40575-40583

2011

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Nuclear fibroblast growth factor 2 (FGF2) isoforms inhibit bone marrow stromal cell mineralization through FGF23/FGFR/MAPK in vitro

Journal of bone and mineral research, 2013-01, Vol.28 (1), p.35-45

2013

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Inhibition of FGFR Signaling Partially Rescues Hypophosphatemic Rickets in HMWFGF2 Tg Male Mice

Endocrinology (Philadelphia), 2017-10, Vol.158 (10), p.3629-3646

2017

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Effects of low dose FGF-2 and BMP-2 on healing of calvarial defects in old mice

Experimental gerontology, 2015-04, Vol.64, p.62-69

2015

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Fibroblast Growth Factor 23 Neutralizing Antibody Ameliorates Abnormal Renal Phosphate Handling in Sickle Cell Disease Mice

Endocrinology (Philadelphia), 2023-11, Vol.164 (12)

2023

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Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells

Bone (New York, N.Y.), 2010-08, Vol.47 (2), p.360-370

2010

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Fibroblast Growth Factor-2 Isoform (Low Molecular Weight/18 kDa) Overexpression in Preosteoblast Cells Promotes Bone Regeneration in Critical Size Calvarial Defects in Male Mice

Endocrinology (Philadelphia), 2014-03, Vol.155 (3), p.965-974

2014

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FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation

Bone Reports, 2018-12, Vol.9, p.136-144

2018

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Nuclear Isoforms of Fibroblast Growth Factor 2 Are Novel Inducers of Hypophosphatemia via Modulation of FGF23 and KLOTHO

The Journal of biological chemistry, 2010-01, Vol.285 (4), p.2834-2846

2010

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FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2

Endocrinology (Philadelphia), 2018-06, Vol.159 (6), p.2386-2396

2018

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Reduced expression and function of bone morphogenetic protein-2 in bones of Fgf2 null mice

Journal of cellular biochemistry, 2008-04, Vol.103 (6), p.1975-1988

2008

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Exported 18-kDa Isoform of Fibroblast Growth Factor-2 Is a Critical Determinant of Bone Mass in Mice

The Journal of biological chemistry, 2009-01, Vol.284 (5), p.3170-3182

2009

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Endogenous FGF-2 is critically important in PTH anabolic effects on bone

Journal of cellular physiology, 2009-04, Vol.219 (1), p.143-151

2009

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Endogenous FGF‐2 levels impact FGF‐2/BMP‐2 growth factor delivery dosing in aged murine calvarial bone defects

Journal of biomedical materials research. Part A, 2021-12, Vol.109 (12), p.2545-2555

2021

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Fibroblast growth factor 2 positively regulates expression of activating transcription factor 4 in osteoblasts

Biochemical and biophysical research communications, 2010-01, Vol.391 (1), p.335-339

2010

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FGF-2 enhances Runx-2/Smads nuclear localization in BMP-2 canonical signaling in osteoblasts

Journal of cellular physiology, 2013-11, Vol.228 (11), p.2149-2158

2013

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FGFR Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt Signaling in FGF2 High Molecular Weight Isoform Transgenic Mice

Journal of cellular biochemistry, 2016-09, Vol.117 (9), p.1991-2000

2016

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FGF23 Neutralizing Antibody Partially Improves Bone Mineralization Defect of HMWFGF2 Isoforms in Transgenic Female Mice

Journal of bone and mineral research, 2018-07, Vol.33 (7), p.1347-1361

2018

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Effects of GBT1118, a voxelotor analog, on bone disease in sickle cell disease mice

Inhibition of FGFR Signaling Partially Rescues Osteoarthritis in Mice Overexpressing High Molecular Weight FGF2 Isoforms

Fibroblast growth factor-2, bone homeostasis and fracture repair

Gait disturbances and muscle dysfunction in fibroblast growth factor 2 knockout mice

Ablation of low‐molecular‐weight FGF2 isoform accelerates murine osteoarthritis while loss of high‐molecular‐weight FGF2 isoforms offers protection

FGF receptor inhibitor BGJ398 partially rescues osteoarthritis-like phenotype in older high molecular weight FGF2 transgenic mice via multiple mechanisms

Role of fibroblast growth factor 2 and wnt signaling in anabolic effects of parathyroid hormone on bone formation

Fibroblast Growth Factor 2 Stimulation of Osteoblast Differentiation and Bone Formation Is Mediated by Modulation of the Wnt Signaling Pathway

Nuclear fibroblast growth factor 2 (FGF2) isoforms inhibit bone marrow stromal cell mineralization through FGF23/FGFR/MAPK in vitro

Inhibition of FGFR Signaling Partially Rescues Hypophosphatemic Rickets in HMWFGF2 Tg Male Mice

Effects of low dose FGF-2 and BMP-2 on healing of calvarial defects in old mice

Fibroblast Growth Factor 23 Neutralizing Antibody Ameliorates Abnormal Renal Phosphate Handling in Sickle Cell Disease Mice

Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells

Fibroblast Growth Factor-2 Isoform (Low Molecular Weight/18 kDa) Overexpression in Preosteoblast Cells Promotes Bone Regeneration in Critical Size Calvarial Defects in Male Mice

FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation

Nuclear Isoforms of Fibroblast Growth Factor 2 Are Novel Inducers of Hypophosphatemia via Modulation of FGF23 and KLOTHO

FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2

Reduced expression and function of bone morphogenetic protein-2 in bones of Fgf2 null mice

Exported 18-kDa Isoform of Fibroblast Growth Factor-2 Is a Critical Determinant of Bone Mass in Mice

Endogenous FGF-2 is critically important in PTH anabolic effects on bone

Endogenous FGF‐2 levels impact FGF‐2/BMP‐2 growth factor delivery dosing in aged murine calvarial bone defects

Fibroblast growth factor 2 positively regulates expression of activating transcription factor 4 in osteoblasts

FGF-2 enhances Runx-2/Smads nuclear localization in BMP-2 canonical signaling in osteoblasts

FGFR Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt Signaling in FGF2 High Molecular Weight Isoform Transgenic Mice

FGF23 Neutralizing Antibody Partially Improves Bone Mineralization Defect of HMWFGF2 Isoforms in Transgenic Female Mice

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