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Hyperpolarized 13C metabolic imaging using dissolution dynamic nuclear polarization

Journal of magnetic resonance imaging, 2012-12, Vol.36 (6), p.1314-1328

2012

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Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading

Cancer research (Chicago, Ill.), 2008-10, Vol.68 (20), p.8607-8615

2008

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Dynamic Imaging of Glucose and Lactate Metabolism by 13C-MRS without Hyperpolarization

Scientific reports, 2019-03, Vol.9 (1), p.3410-3410, Article 3410

2019

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In vivo assessment of intracellular redox state in rat liver using hyperpolarized [1‐13C]Alanine

Magnetic resonance in medicine, 2017-05, Vol.77 (5), p.1741-1748

2017

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Metabolic imaging in the anesthetized rat brain using hyperpolarized [1-13C] pyruvate and [1-13C] ethyl pyruvate

Magnetic resonance in medicine, 2010-05, Vol.63 (5), p.1137-1143

2010

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Measuring mitochondrial metabolism in rat brain in vivo using MR Spectroscopy of hyperpolarized [2-13C]pyruvate

NMR in biomedicine, 2013-10, Vol.26 (10), p.1197-1203

2013

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Hyperpolarized C-13 spectroscopic imaging of the TRAMP mouse at 3T-Initial experience

Magnetic resonance in medicine, 2007-12, Vol.58 (6), p.1099-1106

2007

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Cerebral dynamics and metabolism of hyperpolarized [1- C]pyruvate using time-resolved MR spectroscopic imaging

Journal of cerebral blood flow and metabolism, 2010-10, Vol.30 (10), p.1734-1741

2010

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PKM2 activation sensitizes cancer cells to growth inhibition by 2-deoxy-D-glucose

Oncotarget, 2017-10, Vol.8 (53), p.90959-90968

2017

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Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2-13C2]pyruvate in vivo

NMR in biomedicine, 2012-02, Vol.25 (2), p.305-311

2012

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Dynamic and high‐resolution metabolic imaging of hyperpolarized [1‐13C]‐pyruvate in the rat brain using a high‐performance gradient insert

Magnetic resonance in medicine, 2011-05, Vol.65 (5), p.1228-1233

2011

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Proton HR-MAS spectroscopy and quantitative pathologic analysis of MRI/3D-MRSI-targeted postsurgical prostate tissues

Magnetic resonance in medicine, 2003-11, Vol.50 (5), p.944-954

2003

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In vivo measurement of ethanol metabolism in the rat liver using magnetic resonance spectroscopy of hyperpolarized [1-13C]pyruvate

Magnetic resonance in medicine, 2009-08, Vol.62 (2), p.307-313

2009

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In vivo MRSI of hyperpolarized [1-13C]pyruvate metabolism in rat hepatocellular carcinoma

NMR in biomedicine, 2011-06, Vol.24 (5), p.506-513

2011

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Generation of hyperpolarized substrates by secondary labeling with [1,1-¹³C] acetic anhydride

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (14), p.5503-5507

2009

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Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate

Science translational medicine, 2013-08, Vol.5 (198), p.198ra108

2013

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Deuterium metabolic imaging for 3D mapping of glucose metabolism in humans with central nervous system lesions at 3T

Magnetic resonance in medicine, 2024-01, Vol.91 (1), p.39-50

2024

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Investigating the origin of the 13 C lactate signal in the anesthetized healthy rat brain in vivo after hyperpolarized [1- 13 C]pyruvate injection

NMR in biomedicine, 2024-03, Vol.37 (3), p.e5073

2024

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Investigating the origin of the 13C lactate signal in the anesthetized healthy rat brain in vivo after hyperpolarized [1‐13C]pyruvate injection

NMR in biomedicine, 2024-03, Vol.37 (3), p.e5073-n/a

2024

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Proton magnetic resonance spectroscopy assessment of neonatal brain metabolism during cardiopulmonary bypass surgery

NMR in biomedicine, 2022-09, Vol.35 (9), p.e4752-n/a

2022

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Hyperpolarized NMR study of the impact of pyruvate dehydrogenase kinase inhibition on the pyruvate dehydrogenase and TCA flux in type 2 diabetic rat muscle

Pflügers Archiv, 2021-11, Vol.473 (11), p.1761-1773

2021

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Hyperpolarized (13)C-lactate to (13)C-bicarbonate ratio as a biomarker for monitoring the acute response of anti-vascular endothelial growth factor (anti-VEGF) treatment

NMR in biomedicine, 2016-05, Vol.29 (5), p.650-659

2016

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Volumetric spiral chemical shift imaging of hyperpolarized [2-13c]pyruvate in a rat c6 glioma model

Magnetic resonance in medicine, 2016-03, Vol.75 (3), p.973-984

2016

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Exchange-linked dissolution agents in dissolution-DNP (13)C metabolic imaging

Magnetic resonance in medicine, 2013-10, Vol.70 (4), p.936

2013

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Spectral-spatial excitation for rapid imaging of DNP compounds

NMR in biomedicine, 2011-10, Vol.24 (8), p.988-996

2011

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Hyperpolarized 13C metabolic imaging using dissolution dynamic nuclear polarization

Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading

Dynamic Imaging of Glucose and Lactate Metabolism by 13C-MRS without Hyperpolarization

In vivo assessment of intracellular redox state in rat liver using hyperpolarized [1‐13C]Alanine

Metabolic imaging in the anesthetized rat brain using hyperpolarized [1-13C] pyruvate and [1-13C] ethyl pyruvate

Measuring mitochondrial metabolism in rat brain in vivo using MR Spectroscopy of hyperpolarized [2-13C]pyruvate

Hyperpolarized C-13 spectroscopic imaging of the TRAMP mouse at 3T-Initial experience

Cerebral dynamics and metabolism of hyperpolarized [1- C]pyruvate using time-resolved MR spectroscopic imaging

PKM2 activation sensitizes cancer cells to growth inhibition by 2-deoxy-D-glucose

Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2-13C2]pyruvate in vivo

Dynamic and high‐resolution metabolic imaging of hyperpolarized [1‐13C]‐pyruvate in the rat brain using a high‐performance gradient insert

Proton HR-MAS spectroscopy and quantitative pathologic analysis of MRI/3D-MRSI-targeted postsurgical prostate tissues

In vivo measurement of ethanol metabolism in the rat liver using magnetic resonance spectroscopy of hyperpolarized [1-13C]pyruvate

In vivo MRSI of hyperpolarized [1-13C]pyruvate metabolism in rat hepatocellular carcinoma

Generation of hyperpolarized substrates by secondary labeling with [1,1-¹³C] acetic anhydride

Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate

Deuterium metabolic imaging for 3D mapping of glucose metabolism in humans with central nervous system lesions at 3T

Investigating the origin of the 13 C lactate signal in the anesthetized healthy rat brain in vivo after hyperpolarized [1- 13 C]pyruvate injection

Investigating the origin of the 13C lactate signal in the anesthetized healthy rat brain in vivo after hyperpolarized [1‐13C]pyruvate injection

Proton magnetic resonance spectroscopy assessment of neonatal brain metabolism during cardiopulmonary bypass surgery

Hyperpolarized NMR study of the impact of pyruvate dehydrogenase kinase inhibition on the pyruvate dehydrogenase and TCA flux in type 2 diabetic rat muscle

Hyperpolarized (13)C-lactate to (13)C-bicarbonate ratio as a biomarker for monitoring the acute response of anti-vascular endothelial growth factor (anti-VEGF) treatment

Volumetric spiral chemical shift imaging of hyperpolarized [2-13c]pyruvate in a rat c6 glioma model

Exchange-linked dissolution agents in dissolution-DNP (13)C metabolic imaging

Spectral-spatial excitation for rapid imaging of DNP compounds

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