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Shaping of Natural Killer Cell Antitumor Activity by Ex Vivo Cultivation

Frontiers in immunology, 2017-04, Vol.8, p.458-458

2017

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Editorial: Translating NK cell scientific research to clinical product manufacturing

Frontiers in immunology, 2023-08, Vol.14, p.1229417-1229417

2023

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Fully automated expansion and activation of clinical-grade natural killer cells for adoptive immunotherapy

Cytotherapy (Oxford, England), 2015-05, Vol.17 (5), p.621-632

2015

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Development of Automated Separation, Expansion, and Quality Control Protocols for Clinical-Scale Manufacturing of Primary Human NK Cells and Alpharetroviral Chimeric Antigen Receptor Engineering

Human gene therapy. Part B. Methods, 2019-06, Vol.30 (3), p.102-120

2019

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Influence of Irradiated Peripheral Blood Mononuclear Cells on Both Ex Vivo Proliferation of Human Natural Killer Cells and Change in Cellular Property

Frontiers in immunology, 2017-07, Vol.8, p.854-854

2017

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Optimization of Human NK Cell Manufacturing: Fully Automated Separation, Improved Ex Vivo Expansion Using IL-21 with Autologous Feeder Cells, and Generation of Anti-CD123-CAR-Expressing Effector Cells

Human gene therapy, 2017-10, Vol.28 (10), p.897-913

2017

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Highly efficient IL-21 and feeder cell-driven ex vivo expansion of human NK cells with therapeutic activity in a xenograft mouse model of melanoma

Oncoimmunology, 2016-09, Vol.5 (9), p.e1219007-e1219007

2016

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Depletion of T-cell receptor alpha/beta and CD19 positive cells from apheresis products with the CliniMACS device

Cytotherapy (Oxford, England), 2013-10, Vol.15 (10), p.1253-1258

2013

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Fully automated concentration of large scale cultured cells for immune therapy using the clinimacs prodigy

Cytotherapy (Oxford, England), 2017-05, Vol.19 (5), p.e7-e7

2017

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LB13 - Fully automated concentration of large scale cultured cells for immune therapy using the clinimacs prodigy

Cytotherapy (Oxford, England), 2017-05, Vol.19 (5), p.e7-e7

2017

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Standardized and flexible eight colour flow cytometry panels harmonized between different laboratories to study human NK cell phenotype and function

Scientific reports, 2017-03, Vol.7 (1), p.43873-43873, Article 43873

2017

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Natural Killer Group 2D Ligand Depletion Reconstitutes Natural Killer Cell Immunosurveillance of Head and Neck Squamous Cell Carcinoma

Frontiers in immunology, 2017-04, Vol.8, p.387-387

2017

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Automation of cellular therapy product manufacturing: results of a split validation comparing CD34 selection of peripheral blood stem cell apheresis product with a semi-manual vs. an automatic procedure

Journal of translational medicine, 2016-03, Vol.14 (75), p.76-76, Article 76

2016

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Automated CD34+ cell isolation of peripheral blood stem cell apheresis product

Cytotherapy (Oxford, England), 2015-10, Vol.17 (10), p.1465-1471

2015

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Umbilical cord blood NK cells offer multiple advantages for cancer immunotherapy: lessons learned from Glycostem’s orphan drug oNKord

Cell and Gene Therapy Insights, 2021-01, Vol.7 (12), p.1795-1805

Huppert, Volker

2021

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Next Level of Automated Cell Processing System for Flexible Manufacturing of Cellular Products

Blood, 2010-11, Vol.116 (21), p.1186-1186

2010

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Maintenance with Histamine and IL-2 Induces a Marked Expansion of Activated CD56bright NK Cells in Acute Myeloid Leukemia

Blood, 2014-12, Vol.124 (21), p.1422-1422

2014

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Cell-Based Assays Using Leukocyte Populations Isolated Directly From Whole Blood

Blood, 2012-11, Vol.120 (21), p.4842-4842

2012

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Integrated Clinical Scale Manufacturing System for Cellular Products Derived by Magnetic Cell Separation, Centrifugation and Cell Culture

Chemie ingenieur technik, 2013-02, Vol.85 (1-2), p.103-110

2013

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CliniMACS® Cell Enrichment Using NKp46 — A Large Scale, Single-Step NK Cell Isolation Method

Blood, 2007-11, Vol.110 (11), p.3877-3877

2007

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Design of artifical tumor cells to induce Natural Killer cell proliferation (42.13)

The Journal of immunology (1950), 2009-04, Vol.182 (1_Supplement), p.42-42.13

2009

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Cell Separation System for Fully Automated Clinical Scale Separation of CD133+ Cells From Bone Marrow Aspirates

Blood, 2010-11, Vol.116 (21), p.1188-1188

2010

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KIR Positive Subsets of Human CD56+CD3+ NKT Cells Are Different in Frequency from Equivalant KIR Positive CD56+CD3- NK Cell Subsets

Blood, 2007-11, Vol.110 (11), p.3878-3878

2007

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High Numbers of NK Cell Clones Can Be Generated by Limiting Dilution in SCGM Medium Supplemented with IL-2, IL-15 and Anti-NKp46 Antibody 9E2

Blood, 2007-11, Vol.110 (11), p.3876-3876

2007

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Transplantation of TcRαβ/CD19 Depleted Stem Cells From Haploidentical Donors: Robust Engraftment and Rapid Immune Reconstitution In Children with High Risk Leukemia

Blood, 2011-11, Vol.118 (21), p.1005-1005

2011

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Shaping of Natural Killer Cell Antitumor Activity by Ex Vivo Cultivation

Editorial: Translating NK cell scientific research to clinical product manufacturing

Fully automated expansion and activation of clinical-grade natural killer cells for adoptive immunotherapy

Development of Automated Separation, Expansion, and Quality Control Protocols for Clinical-Scale Manufacturing of Primary Human NK Cells and Alpharetroviral Chimeric Antigen Receptor Engineering

Influence of Irradiated Peripheral Blood Mononuclear Cells on Both Ex Vivo Proliferation of Human Natural Killer Cells and Change in Cellular Property

Optimization of Human NK Cell Manufacturing: Fully Automated Separation, Improved Ex Vivo Expansion Using IL-21 with Autologous Feeder Cells, and Generation of Anti-CD123-CAR-Expressing Effector Cells

Highly efficient IL-21 and feeder cell-driven ex vivo expansion of human NK cells with therapeutic activity in a xenograft mouse model of melanoma

Depletion of T-cell receptor alpha/beta and CD19 positive cells from apheresis products with the CliniMACS device

Fully automated concentration of large scale cultured cells for immune therapy using the clinimacs prodigy

LB13 - Fully automated concentration of large scale cultured cells for immune therapy using the clinimacs prodigy

Standardized and flexible eight colour flow cytometry panels harmonized between different laboratories to study human NK cell phenotype and function

Natural Killer Group 2D Ligand Depletion Reconstitutes Natural Killer Cell Immunosurveillance of Head and Neck Squamous Cell Carcinoma

Automation of cellular therapy product manufacturing: results of a split validation comparing CD34 selection of peripheral blood stem cell apheresis product with a semi-manual vs. an automatic procedure

Automated CD34+ cell isolation of peripheral blood stem cell apheresis product

Umbilical cord blood NK cells offer multiple advantages for cancer immunotherapy: lessons learned from Glycostem’s orphan drug oNKord

Next Level of Automated Cell Processing System for Flexible Manufacturing of Cellular Products

Maintenance with Histamine and IL-2 Induces a Marked Expansion of Activated CD56bright NK Cells in Acute Myeloid Leukemia

Cell-Based Assays Using Leukocyte Populations Isolated Directly From Whole Blood

Integrated Clinical Scale Manufacturing System for Cellular Products Derived by Magnetic Cell Separation, Centrifugation and Cell Culture

CliniMACS® Cell Enrichment Using NKp46 — A Large Scale, Single-Step NK Cell Isolation Method

Design of artifical tumor cells to induce Natural Killer cell proliferation (42.13)

Cell Separation System for Fully Automated Clinical Scale Separation of CD133+ Cells From Bone Marrow Aspirates

KIR Positive Subsets of Human CD56+CD3+ NKT Cells Are Different in Frequency from Equivalant KIR Positive CD56+CD3- NK Cell Subsets

High Numbers of NK Cell Clones Can Be Generated by Limiting Dilution in SCGM Medium Supplemented with IL-2, IL-15 and Anti-NKp46 Antibody 9E2

Transplantation of TcRαβ/CD19 Depleted Stem Cells From Haploidentical Donors: Robust Engraftment and Rapid Immune Reconstitution In Children with High Risk Leukemia

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