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Single- and Multiple-Dose Pharmacokinetics of Caspofungin in Healthy Men

Antimicrobial Agents and Chemotherapy, 2002-03, Vol.46 (3), p.739-745

2002

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Safety, tolerability and pharmacokinetics of AFN-1252 administered as immediate release tablets in healthy subjects

Future microbiology, 2015-11, Vol.10 (11), p.1805-1813

2015

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Results of two Phase 1, Randomized, Double-blind, Placebo-controlled, Studies (Ascending Single-dose and Multiple-dose Studies) to Determine the Safety, Tolerability, and Pharmacokinetics of Orally Administered LX9211 in Healthy Participants

Clinical therapeutics, 2021-06, Vol.43 (6), p.1029-1050

2021

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The Effect of Verapamil, a P-gp Inhibitor, on the Pharmacokinetics, Safety, and Tolerability of Omadacycline in Healthy Adults: A Phase I, Open-Label, Single-Sequence Study

European journal of drug metabolism and pharmacokinetics, 2021-01, Vol.46 (1), p.85-92

2021

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Integration of modeling and simulation to support changes to ondansetron dosing following a randomized, double-blind, placebo-, and active-controlled thorough QT study

Journal of clinical pharmacology, 2014-11, Vol.54 (11), p.1221-1229

2014

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Absolute Bioavailability and Pharmacokinetics of Treprostinil Sodium Administered by Acute Subcutaneous Infusion

Journal of clinical pharmacology, 2004-01, Vol.44 (1), p.83-88

2004

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FTY720: Placebo-Controlled Study of the Effect on Cardiac Rate and Rhythm in Healthy Subjects

Journal of clinical pharmacology, 2006-08, Vol.46 (8), p.895-904

2006

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Evaluation of Eluxadoline Effect on Cardiac Repolarization

Clinical pharmacology in drug development, 2018-09, Vol.7 (7), p.727-736

2018

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Effects of three fluoroquinolones on QT interval in healthy adults after single doses

Clinical pharmacology and therapeutics, 2003-04, Vol.73 (4), p.292-303

2003

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Effect of pitavastatin vs. rosuvastatin on international normalized ratio in healthy volunteers on steady-state warfarin

Current medical research and opinion, 2012-02, Vol.28 (2), p.187-194

2012

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The ability of atropine to prevent and reverse the negative chronotropic effect of fingolimod in healthy subjects

British journal of clinical pharmacology, 2008-08, Vol.66 (2), p.199-206

2008

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Effect of the thrombin receptor antagonist (PAR-1) vorapaxar on QT/QTc interval in healthy volunteers: A randomized, placebo- and positive-controlled, parallel group trial

Clinical pharmacology in drug development, 2014-01, Vol.3 (1), p.18-24

2014

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A Mechanistic Study to Assess Whether Isoproterenol Can Reverse the Negative Chronotropic Effect of Fingolimod

Journal of clinical pharmacology, 2008-03, Vol.48 (3), p.303-310

2008

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Lack of Drug-Drug Interaction between Mipomersen and Warfarin in Healthy Volunteers

Journal of clinical lipidology, 2013-05, Vol.7 (3), p.276-277

2013

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Single- and Multiple-Dose Pharmacokinetics of Etoricoxib, a Selective Inhibitor of Cyclooxygenase-2, in Man

Journal of clinical pharmacology, 2003-03, Vol.43 (3), p.268-276

2003

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Pharmacokinetics of palonosetron in combination with aprepitant in healthy volunteers

Current medical research and opinion, 2005-04, Vol.21 (4), p.595-601

2005

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Evaluation of Safety and Pharmacokinetics of Consecutive Multiple-Day Dosing of Palonosetron in Healthy Subjects

Journal of clinical pharmacology, 2005-05, Vol.45 (5), p.589-596

2005

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Pharmacokinetics of Treprostinil Sodium Administered by 28-Day Chronic Continuous Subcutaneous Infusion

Journal of clinical pharmacology, 2004-05, Vol.44 (5), p.503-509

2004

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The Effect of Etoricoxib on the Pharmacodynamics and Pharmacokinetics of Warfarin

Journal of clinical pharmacology, 2007-05, Vol.47 (5), p.620-627

2007

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The effect of rofecoxib on the pharmacodynamics and pharmacokinetics of warfarin

Clinical pharmacology and therapeutics, 2000-12, Vol.68 (6), p.626-636

2000

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Effect of Continuous Subcutaneous Treprostinil Therapy on the Pharmacodynamics and Pharmacokinetics of Warfarin

Journal of cardiovascular pharmacology, 2003-06, Vol.41 (6), p.908-915

2003

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A Double-Blind, Placebo-Controlled, and Multiple Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Ono-7746 in Healthy Subjects

Blood, 2011-11, Vol.118 (21), p.4828-4828

2011

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Single Oral Doses of a Novel Thrombopoietin Mimetic ONO-7746 Increase Platelet Counts In Healthy Subjects

Blood, 2011-11, Vol.118 (21), p.4827-4827

2011

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Effect of the acyl-CoA: cholesterol acyltransferase inhibitor DuP 128 on cholesterol absorption and serum cholesterol in humans

Clinical pharmacology and therapeutics, 1994-07, Vol.56 (1), p.65-74

1994

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Pharmacokinetics, Safety, and Tolerability of Single Intravenous Infusions of an Adenosine Agonist, AMP 579, in Healthy Male Volunteers

Journal of clinical pharmacology, 1999-10, Vol.39 (10), p.1044-1052

1999

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Single- and Multiple-Dose Pharmacokinetics of Caspofungin in Healthy Men

Safety, tolerability and pharmacokinetics of AFN-1252 administered as immediate release tablets in healthy subjects

Results of two Phase 1, Randomized, Double-blind, Placebo-controlled, Studies (Ascending Single-dose and Multiple-dose Studies) to Determine the Safety, Tolerability, and Pharmacokinetics of Orally Administered LX9211 in Healthy Participants

The Effect of Verapamil, a P-gp Inhibitor, on the Pharmacokinetics, Safety, and Tolerability of Omadacycline in Healthy Adults: A Phase I, Open-Label, Single-Sequence Study

Integration of modeling and simulation to support changes to ondansetron dosing following a randomized, double-blind, placebo-, and active-controlled thorough QT study

Absolute Bioavailability and Pharmacokinetics of Treprostinil Sodium Administered by Acute Subcutaneous Infusion

FTY720: Placebo-Controlled Study of the Effect on Cardiac Rate and Rhythm in Healthy Subjects

Evaluation of Eluxadoline Effect on Cardiac Repolarization

Effects of three fluoroquinolones on QT interval in healthy adults after single doses

Effect of pitavastatin vs. rosuvastatin on international normalized ratio in healthy volunteers on steady-state warfarin

The ability of atropine to prevent and reverse the negative chronotropic effect of fingolimod in healthy subjects

Effect of the thrombin receptor antagonist (PAR-1) vorapaxar on QT/QTc interval in healthy volunteers: A randomized, placebo- and positive-controlled, parallel group trial

A Mechanistic Study to Assess Whether Isoproterenol Can Reverse the Negative Chronotropic Effect of Fingolimod

Lack of Drug-Drug Interaction between Mipomersen and Warfarin in Healthy Volunteers

Single- and Multiple-Dose Pharmacokinetics of Etoricoxib, a Selective Inhibitor of Cyclooxygenase-2, in Man

Pharmacokinetics of palonosetron in combination with aprepitant in healthy volunteers

Evaluation of Safety and Pharmacokinetics of Consecutive Multiple-Day Dosing of Palonosetron in Healthy Subjects

Pharmacokinetics of Treprostinil Sodium Administered by 28-Day Chronic Continuous Subcutaneous Infusion

The Effect of Etoricoxib on the Pharmacodynamics and Pharmacokinetics of Warfarin

The effect of rofecoxib on the pharmacodynamics and pharmacokinetics of warfarin

Effect of Continuous Subcutaneous Treprostinil Therapy on the Pharmacodynamics and Pharmacokinetics of Warfarin

A Double-Blind, Placebo-Controlled, and Multiple Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Ono-7746 in Healthy Subjects

Single Oral Doses of a Novel Thrombopoietin Mimetic ONO-7746 Increase Platelet Counts In Healthy Subjects

Effect of the acyl-CoA: cholesterol acyltransferase inhibitor DuP 128 on cholesterol absorption and serum cholesterol in humans

Pharmacokinetics, Safety, and Tolerability of Single Intravenous Infusions of an Adenosine Agonist, AMP 579, in Healthy Male Volunteers

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