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The function and regulation of acid‐sensing ion channels (ASICs) and the epithelial Na+ channel (ENaC): IUPHAR Review 19

British journal of pharmacology, 2016-09, Vol.173 (18), p.2671-2701

2016

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ENaC activation by proteases

Acta Physiologica, 2022-05, Vol.235 (1), p.e13811-n/a

2022

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The cells and peripheral representation of sodium taste in mice

Nature (London), 2010-03, Vol.464 (7286), p.297-301

2010

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Analysis of the Hypoxic Response in a Mouse Cortical Collecting Duct-Derived Cell Line Suggests That Esrra Is Partially Involved in Hif1α-Mediated Hypoxia-Inducible Gene Expression in mCCDcl1 Cells

International journal of molecular sciences, 2022-06, Vol.23 (13), p.7262

2022

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Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype

Kidney international, 2019-02, Vol.95 (2), p.375-387

2019

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The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice

The Journal of clinical investigation, 2010-05, Vol.120 (5), p.1627-1635

2010

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Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel

Scientific reports, 2022-09, Vol.12 (1), p.15955-15955, Article 15955

2022

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Colon-Specific Deletion of Epithelial Sodium Channel Causes Sodium Loss and Aldosterone Resistance

Journal of the American Society of Nephrology, 2014-07, Vol.25 (7), p.1453-1464

2014

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Regulation of blood pressure and renal function by NCC and ENaC: lessons from genetically engineered mice

Current opinion in pharmacology, 2015-04, Vol.21, p.60-72

2015

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The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin

eLife, 2015-12, Vol.4, p.e08887

2015

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A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors

Nature communications, 2018-03, Vol.9 (1), p.1199-15, Article 1199

2018

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epidermal barrier function is dependent on the serine protease CAP1/Prss8

The Journal of cell biology, 2005-08, Vol.170 (3), p.487-496

2005

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Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis

Inflammatory bowel diseases, 2016-12, Vol.22 (12), p.2824-2839

2016

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Kidney-Specific CAP1/Prss8-Deficient Mice Maintain ENaC-Mediated Sodium Balance through an Aldosterone Independent Pathway

International journal of molecular sciences, 2022-06, Vol.23 (12), p.6745

2022

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Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion

Scientific reports, 2019-12, Vol.9 (1), p.19540-15, Article 19540

2019

Volltextzugriff (PDF)

The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases

Journal of virology, 2016-05, Vol.90 (9), p.4298-4307

2016

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Salt-Sensitive Hypertension in GR +/- Rats Is Accompanied with Dysregulation in Adrenal Soluble Epoxide Hydrolase and Polyunsaturated Fatty Acid Pathways

International journal of molecular sciences, 2021-12, Vol.22 (24), p.13218

2021

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Epithelial sodium channel and the control of sodium balance: interaction between genetic and environmental factors

Annual review of physiology, 2002-01, Vol.64 (1), p.877-897

2002

Volltextzugriff (PDF)

Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5

The Journal of clinical investigation, 2003-12, Vol.112 (12), p.1906-1914

2003

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Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4

PloS one, 2015-08, Vol.10 (8), p.e0135224

2015

Volltextzugriff (PDF)

Hypoxia-induced inhibition of epithelial Na(+) channels in the lung. Role of Nedd4-2 and the ubiquitin-proteasome pathway

American journal of respiratory cell and molecular biology, 2014-03, Vol.50 (3), p.526-537

2014

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Lessons learned about epithelial sodium channels from transgenic mouse models

Current opinion in nephrology and hypertension, 2022-09, Vol.31 (5), p.493

2022

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Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation

PLoS genetics, 2012-08, Vol.8 (8), p.e1002937-e1002937

2012

Volltextzugriff (PDF)

Kidney-Specific Membrane-Bound Serine Proteases CAP1/Prss8 and CAP3/St14 Affect ENaC Subunit Abundances but Not Its Activity

Cells (Basel, Switzerland), 2023-09, Vol.12 (19), p.2342

2023

Volltextzugriff (PDF)

Mutations of the Serine Protease CAP1/Prss8 Lead to Reduced Embryonic Viability, Skin Defects, and Decreased ENaC Activity

The American journal of pathology, 2012-08, Vol.181 (2), p.605-615

2012

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The function and regulation of acid‐sensing ion channels (ASICs) and the epithelial Na+ channel (ENaC): IUPHAR Review 19

ENaC activation by proteases

The cells and peripheral representation of sodium taste in mice

Analysis of the Hypoxic Response in a Mouse Cortical Collecting Duct-Derived Cell Line Suggests That Esrra Is Partially Involved in Hif1α-Mediated Hypoxia-Inducible Gene Expression in mCCDcl1 Cells

Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype

The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice

Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel

Colon-Specific Deletion of Epithelial Sodium Channel Causes Sodium Loss and Aldosterone Resistance

Regulation of blood pressure and renal function by NCC and ENaC: lessons from genetically engineered mice

The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin

A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors

epidermal barrier function is dependent on the serine protease CAP1/Prss8

Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis

Kidney-Specific CAP1/Prss8-Deficient Mice Maintain ENaC-Mediated Sodium Balance through an Aldosterone Independent Pathway

Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion

The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases

Salt-Sensitive Hypertension in GR +/- Rats Is Accompanied with Dysregulation in Adrenal Soluble Epoxide Hydrolase and Polyunsaturated Fatty Acid Pathways

Epithelial sodium channel and the control of sodium balance: interaction between genetic and environmental factors

Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5

Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4

Hypoxia-induced inhibition of epithelial Na(+) channels in the lung. Role of Nedd4-2 and the ubiquitin-proteasome pathway

Lessons learned about epithelial sodium channels from transgenic mouse models

Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation

Kidney-Specific Membrane-Bound Serine Proteases CAP1/Prss8 and CAP3/St14 Affect ENaC Subunit Abundances but Not Its Activity

Mutations of the Serine Protease CAP1/Prss8 Lead to Reduced Embryonic Viability, Skin Defects, and Decreased ENaC Activity

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