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Abstract 1068: Anti-DR5 agonist IgM antibody IGM-8444 combined with SMAC mimetic birinapant induces strong synergistic tumor cytotoxicity

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.1068-1068

2022

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Abstract 1899: Novel combinations of aplitabart, a DR5 agonist IgM antibody, with ADCs or chemotherapeutic agents lead to robust anti-tumor responses in solid tumor models

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.1899-1899

2024

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Abstract 2740: High-throughput and sensitive quantification of circulating tumor DNA

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2740-2740

2017

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Abstract 52: Mechanistic evaluation of anti-DR5 IgM antibody IGM-8444 with potent tumor cytotoxicity, without in vitro hepatotoxicity

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.52-52

2021

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Abstract 6123: Characterization of the synergistic tumor cytotoxicity of agonistic DR5 IgM antibody IGM-8444 with chemotherapeutic agents

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.6123-6123

2023

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Abstract CT009: Targeting MUC16 with the THIOMABTM-drug conjugate DMUC4064A in patients with platinum-resistant ovarian cancer: a Phase I escalation study

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.CT009-CT009

2017

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Abstract CT036: Targeting MUC16 with the THIOMABTM-drug conjugate DMUC4064A in patients with platinum-resistant ovarian cancer: A phase I expansion study

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.CT036-CT036

2018

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Abstract P2-11-05: ER pathway activity signature as a biomarker for endocrine agent GDC-9545

Cancer research (Chicago, Ill.), 2020-02, Vol.80 (4_Supplement), p.P2-P2-11-05

2020

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Abstract P5-11-07: Real-world predictors of first-line treatment and descriptive outcomes in HR+/HER2− metastatic breast cancer patients in the US

Cancer research (Chicago, Ill.), 2020-02, Vol.80 (4_Supplement), p.P5-P5-11-07

2020

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Activation of caspases triggered by cytochrome c in vitro

FEBS letters, 1998-04, Vol.426 (1), p.151-154

1998

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Activation of caspases triggered by cytochrome c in vitro 1

FEBS letters, 1998-04, Vol.426 (1), p.151-154

1998

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The Anti-Tumor Activity of Igm-8444, an Agonistic Death Receptor 5 (DR5) IgM Antibody, Is Sensitized in Combination with Chemotherapy and Bcl-2 Inhibitors in NHL and AML

Blood, 2020-11, Vol.136 (Supplement 1), p.43-44

2020

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Apoptosis

Chemistry & biology, 2000-02, Vol.7 (2), p.R48-R49

Humke, Eric W

2000

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Caspase-9 Can Be Activated without Proteolytic Processing

The Journal of biological chemistry, 1999-03, Vol.274 (13), p.8359-8362

1999

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Caspase regulation in inflammation

Humke, Eric W

2004

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Corrigendum to: Activation of caspases triggered by cytochrome c in vitro (FEBS 20097) : [ FEBS Letters 426 (1998) 151–154]

FEBS letters, 1998-05, Vol.428 (3), p.309-309

1998

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ERICE, a Novel FLICE-activatable Caspase

The Journal of biological chemistry, 1998-06, Vol.273 (25), p.15702-15707

1998

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The Evolving Role of Chemotherapy and Predictive Markers in Early-stage Non-small-cell Lung Cancer

European oncology & haematology, 2011, Vol.7 (2), p.109

2011

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High-Throughput and Sensitive Quantification of Circulating Tumor DNA by Microfluidic-Based Multiplex PCR and Next-Generation Sequencing

The Journal of molecular diagnostics : JMD, 2017-11, Vol.19 (6), p.921-932

2017

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ICEBERG

Cell, 2000-09, Vol.103 (1), p.99-111

2000

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ICEBERG: A Novel Inhibitor of Interleukin-1β Generation

Cell, 2000-09, Vol.103 (1), p.99-111

2000

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Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips

Lab on a chip, 2014-01, Vol.14 (1), p.78-88

2014

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Kif3a is necessary for initiation and maintenance of medulloblastoma

Carcinogenesis (New York), 2013-06, Vol.34 (6), p.1382-1392

2013

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Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer

Trends in molecular medicine, 2010-08, Vol.16 (8), p.337-348

2010

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Abstract 1068: Anti-DR5 agonist IgM antibody IGM-8444 combined with SMAC mimetic birinapant induces strong synergistic tumor cytotoxicity

Abstract 1899: Novel combinations of aplitabart, a DR5 agonist IgM antibody, with ADCs or chemotherapeutic agents lead to robust anti-tumor responses in solid tumor models

Abstract 2740: High-throughput and sensitive quantification of circulating tumor DNA

Abstract 52: Mechanistic evaluation of anti-DR5 IgM antibody IGM-8444 with potent tumor cytotoxicity, without in vitro hepatotoxicity

Abstract 6123: Characterization of the synergistic tumor cytotoxicity of agonistic DR5 IgM antibody IGM-8444 with chemotherapeutic agents

Abstract CT009: Targeting MUC16 with the THIOMABTM-drug conjugate DMUC4064A in patients with platinum-resistant ovarian cancer: a Phase I escalation study

Abstract CT036: Targeting MUC16 with the THIOMABTM-drug conjugate DMUC4064A in patients with platinum-resistant ovarian cancer: A phase I expansion study

Abstract P2-11-05: ER pathway activity signature as a biomarker for endocrine agent GDC-9545

Abstract P5-11-07: Real-world predictors of first-line treatment and descriptive outcomes in HR+/HER2− metastatic breast cancer patients in the US

Activation of caspases triggered by cytochrome c in vitro

Activation of caspases triggered by cytochrome c in vitro 1

The Anti-Tumor Activity of Igm-8444, an Agonistic Death Receptor 5 (DR5) IgM Antibody, Is Sensitized in Combination with Chemotherapy and Bcl-2 Inhibitors in NHL and AML

Apoptosis

Caspase-9 Can Be Activated without Proteolytic Processing

Caspase regulation in inflammation

Corrigendum to: Activation of caspases triggered by cytochrome c in vitro (FEBS 20097) : [ FEBS Letters 426 (1998) 151–154]

ERICE, a Novel FLICE-activatable Caspase

The Evolving Role of Chemotherapy and Predictive Markers in Early-stage Non-small-cell Lung Cancer

High-Throughput and Sensitive Quantification of Circulating Tumor DNA by Microfluidic-Based Multiplex PCR and Next-Generation Sequencing

ICEBERG

ICEBERG: A Novel Inhibitor of Interleukin-1β Generation

Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips

Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochipsElectronic supplementary information (ESI) available: Fig. S1-S12, Movies S1-S3. See DOI: 10.1039/c3lc50580d

Kif3a is necessary for initiation and maintenance of medulloblastoma

Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer

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