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Cigarette Smoke Silences Innate Lymphoid Cell Function and Facilitates an Exacerbated Type I Interleukin-33-Dependent Response to Infection

Immunity (Cambridge, Mass.), 2015-03, Vol.42 (3), p.566-579

2015

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IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity

Nature immunology, 2016-06, Vol.17 (6), p.646-655

2016

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c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies

Nature immunology, 2019-08, Vol.20 (8), p.992-1003

2019

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Novel mechanisms of action contributing to benralizumab's potent anti-eosinophilic activity

The European respiratory journal, 2022-03, Vol.59 (3), p.2004306

2022

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IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration

Nature communications, 2020-09, Vol.11 (1), p.4786-4786, Article 4786

2020

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S100A9 induced inflammatory responses are mediated by distinct damage associated molecular patterns (DAMP) receptors in vitro and in vivo

PloS one, 2015-02, Vol.10 (2), p.e0115828-e0115828

2015

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IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization

Journal of allergy and clinical immunology, 2013-01, Vol.131 (1), p.187-200.e8

2013

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Eosinophils, basophils and type 2 immune microenvironments in COPD-affected lung tissue

The European respiratory journal, 2020-05, Vol.55 (5), p.1900110

2020

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MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Journal of allergy and clinical immunology, 2010-06, Vol.125 (6), p.1344-1353.e2

2010

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Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo

The Journal of experimental medicine, 2014-07, Vol.211 (8), p.1657-1672

2014

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A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure

PloS one, 2014-02, Vol.9 (2), p.e88714

2014

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Proteomic profiling of serum identifies a molecular signature that correlates with clinical outcomes in COPD

PloS one, 2022-12, Vol.17 (12), p.e0277357-e0277357

2022

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Tissue kallikrein regulates alveolar macrophage apoptosis early in influenza virus infection

American journal of physiology. Lung cellular and molecular physiology, 2019-06, Vol.316 (6), p.L1127-L1140

2019

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CCR3 is a target for age-related macular degeneration diagnosis and therapy

Nature (London), 2009-07, Vol.460 (7252), p.225-230

2009

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IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice

PloS one, 2011-12, Vol.6 (12), p.e28457-e28457

2011

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A Critical Role for Eosinophils in Allergic Airways Remodeling

Science (American Association for the Advancement of Science), 2004-09, Vol.305 (5691), p.1776-1779

2004

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Kallikrein-Related Peptidase 5 Contributes to H3N2 Influenza Virus Infection in Human Lungs

Journal of virology, 2017-08, Vol.91 (16)

2017

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Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice

Journal of allergy and clinical immunology, 2011-06, Vol.127 (6), p.1552-1561.e1

2011

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Persistence of pulmonary tertiary lymphoid tissues and anti-nuclear antibodies following cessation of cigarette smoke exposure

Respiratory research, 2014-04, Vol.15 (1), p.49-49, Article 49

2014

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The Murine CCR3 Receptor Regulates Both the Role of Eosinophils and Mast Cells in Allergen-Induced Airway Inflammation and Hyperresponsiveness

Proceedings of the National Academy of Sciences - PNAS, 2002-02, Vol.99 (3), p.1479-1484

2002

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Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

Nature immunology, 2016-06, Vol.17 (6), p.626-635

2016

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A role for the C3a anaphylatoxin receptor in the effector phase of asthma

Nature (London), 2000-08, Vol.406 (6799), p.998-1001

2000

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Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice

Respiratory research, 2012-09, Vol.13 (1), p.81-81, Article 81

2012

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Isolation, Culture, and Induction of Plasticity in ILC2s

Methods in molecular biology (Clifton, N.J.), 2020, Vol.2121, p.115

2020

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Essential role for the C5a receptor in regulating the effector phase of synovial infiltration and joint destruction in experimental arthritis

The Journal of experimental medicine, 2002-12, Vol.196 (11), p.1461-1471

2002

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Cigarette Smoke Silences Innate Lymphoid Cell Function and Facilitates an Exacerbated Type I Interleukin-33-Dependent Response to Infection

IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity

c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies

Novel mechanisms of action contributing to benralizumab's potent anti-eosinophilic activity

IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration

S100A9 induced inflammatory responses are mediated by distinct damage associated molecular patterns (DAMP) receptors in vitro and in vivo

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization

Eosinophils, basophils and type 2 immune microenvironments in COPD-affected lung tissue

MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo

A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure

Proteomic profiling of serum identifies a molecular signature that correlates with clinical outcomes in COPD

Tissue kallikrein regulates alveolar macrophage apoptosis early in influenza virus infection

CCR3 is a target for age-related macular degeneration diagnosis and therapy

IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice

A Critical Role for Eosinophils in Allergic Airways Remodeling

Kallikrein-Related Peptidase 5 Contributes to H3N2 Influenza Virus Infection in Human Lungs

Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice

Persistence of pulmonary tertiary lymphoid tissues and anti-nuclear antibodies following cessation of cigarette smoke exposure

The Murine CCR3 Receptor Regulates Both the Role of Eosinophils and Mast Cells in Allergen-Induced Airway Inflammation and Hyperresponsiveness

Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

A role for the C3a anaphylatoxin receptor in the effector phase of asthma

Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice

Isolation, Culture, and Induction of Plasticity in ILC2s

Essential role for the C5a receptor in regulating the effector phase of synovial infiltration and joint destruction in experimental arthritis

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