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Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling

European journal of pharmaceutical sciences, 2014-12, Vol.65, p.156-166

2014

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MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid

International journal of cancer, 2005-09, Vol.116 (5), p.824-829

2005

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In silico identification of potential cholestasis-inducing agents via modeling of Na(+)-dependent taurocholate cotransporting polypeptide substrate specificity

Toxicological sciences, 2012-09, Vol.129 (1), p.35-48

2012

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Evaluation of BepanGel Hydrogel Efficacy and Tolerability Using an Abrasive Wound Model in a Within-Person, Single-Center, Randomized, Investigator-Blind Clinical Investigation

Dermatology and therapy, 2020-10, Vol.10 (5), p.1075-1088

2020

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Evidence for Two Interacting Ligand Binding Sites in Human Multidrug Resistance Protein 2 (ATP Binding Cassette C2)

The Journal of biological chemistry, 2003-06, Vol.278 (26), p.23538-23544

2003

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Interaction of fluvastatin with the liver-specific Na +-dependent taurocholate cotransporting polypeptide (NTCP)

European journal of pharmaceutical sciences, 2011-11, Vol.44 (4), p.487-496

2011

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Semi-mechanistic physiologically-based pharmacokinetic modeling of clinical glibenclamide pharmacokinetics and drug–drug-interactions

European journal of pharmaceutical sciences, 2013-08, Vol.49 (5), p.819-828

2013

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Assessing safety and efficacy of directed P-glycoprotein inhibition to improve the pharmacokinetic properties of saquinavir coadministered with ritonavir

The Journal of pharmacology and experimental therapeutics, 2003-02, Vol.304 (2), p.596

2003

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Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

The Journal of clinical investigation, 1999-11, Vol.104 (10), p.1441-1447

1999

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Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs

AIDS (London), 2002-11, Vol.16 (17), p.2295-2301

2002

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Low systemic exposure of oral docetaxel in mice resulting from extensive first-pass metabolism is boosted by ritonavir

Cancer research (Chicago, Ill.), 2002-11, Vol.62 (21), p.6158-6164

2002

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Stable overexpression of Pregnane X receptor in HepG2 cells increases its potential for bioartificial liver application

Liver transplantation, 2010-09, Vol.16 (9), p.1075-1085

2010

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Significance of P-glycoprotein for the pharmacology and clinical use of HIV protease inhibitors

AIDS (London), 2000-02, Vol.14 (3), p.237-242

2000

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In vivo visualization and quantification of (Disturbed) Oatp-mediated hepatic uptake and Mrp2-mediated biliary excretion of 99mTc-mebrofenin in mice

The Journal of nuclear medicine (1978), 2013-04, Vol.54 (4), p.624

2013

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P-Glycoprotein Limits Oral Availability, Brain, and Fetal Penetration of Saquinavir Even with High Doses of Ritonavir

Molecular pharmacology, 2001-04, Vol.59 (4), p.806-813

2001

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In Vivo Visualization and Quantification of (Disturbed) Oatp-Mediated Hepatic Uptake and Mrp2-Mediated Biliary Excretion of 99m Tc-Mebrofenin in Mice

Journal of Nuclear Medicine, 2013-04, Vol.54 (4), p.624-630

2013

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In Vivo Visualization and Quantification of (Disturbed) Oatp-Mediated Hepatic Uptake and Mrp2-Mediated Biliary Excretion of ^sup 99m^Tc-Mebrofenin in Mice

The Journal of nuclear medicine (1978), 2013-04, Vol.54 (4), p.624

2013

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Stable overexpression of Pregnane X receptor in HepG2 cells increases its potential for bioartificial liver application: PXR Overexpression in HEPG2 for a Bioartificial Liver

Liver transplantation, 2010-09, Vol.16 (9), p.1075-1085

2010

Volltextzugriff (PDF)

Significance of P-glycoprotein for the pharmacology and clinical use of HIV protease inhibitors

AIDS (London), 2000-02, Vol.14 (3), p.235-236

2000

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Trends in Use and Perceptions About Triplet Chemotherapy Plus Bevacizumab for Metastatic Colorectal Cancer

JAMA network open, 2021-09, Vol.4 (9), p.e2124766

2021

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Cost-effectiveness of apixaban compared to other anticoagulants in patients with atrial fibrillation in the real-world and trial settings

PloS one, 2019-09, Vol.14 (9), p.e0222658

2019

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Deep learning–assisted prostate cancer detection on bi-parametric MRI: minimum training data size requirements and effect of prior knowledge

European radiology, 2022-04, Vol.32 (4), p.2224-2234

2022

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Neonatal neuroimaging findings in inborn errors of metabolism

Journal of magnetic resonance imaging, 2013-02, Vol.37 (2), p.294-312

2013

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Domains and determinants of retirement timing: A systematic review of longitudinal studies

BMC public health, 2018-08, Vol.18 (1), p.1083-1083, Article 1083

2018

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Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling

MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid

In silico identification of potential cholestasis-inducing agents via modeling of Na(+)-dependent taurocholate cotransporting polypeptide substrate specificity

Evaluation of BepanGel Hydrogel Efficacy and Tolerability Using an Abrasive Wound Model in a Within-Person, Single-Center, Randomized, Investigator-Blind Clinical Investigation

Evidence for Two Interacting Ligand Binding Sites in Human Multidrug Resistance Protein 2 (ATP Binding Cassette C2)

Interaction of fluvastatin with the liver-specific Na +-dependent taurocholate cotransporting polypeptide (NTCP)

Semi-mechanistic physiologically-based pharmacokinetic modeling of clinical glibenclamide pharmacokinetics and drug–drug-interactions

Assessing safety and efficacy of directed P-glycoprotein inhibition to improve the pharmacokinetic properties of saquinavir coadministered with ritonavir

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs

Low systemic exposure of oral docetaxel in mice resulting from extensive first-pass metabolism is boosted by ritonavir

Stable overexpression of Pregnane X receptor in HepG2 cells increases its potential for bioartificial liver application

Significance of P-glycoprotein for the pharmacology and clinical use of HIV protease inhibitors

In vivo visualization and quantification of (Disturbed) Oatp-mediated hepatic uptake and Mrp2-mediated biliary excretion of 99mTc-mebrofenin in mice

P-Glycoprotein Limits Oral Availability, Brain, and Fetal Penetration of Saquinavir Even with High Doses of Ritonavir

A DGGE system for comprehensive mutation screening of BRCA1 and BRCA2: application in a Dutch cancer clinic setting

In Vivo Visualization and Quantification of (Disturbed) Oatp-Mediated Hepatic Uptake and Mrp2-Mediated Biliary Excretion of 99m Tc-Mebrofenin in Mice

In Vivo Visualization and Quantification of (Disturbed) Oatp-Mediated Hepatic Uptake and Mrp2-Mediated Biliary Excretion of ^sup 99m^Tc-Mebrofenin in Mice

Stable overexpression of Pregnane X receptor in HepG2 cells increases its potential for bioartificial liver application: PXR Overexpression in HEPG2 for a Bioartificial Liver

Significance of P-glycoprotein for the pharmacology and clinical use of HIV protease inhibitors

Trends in Use and Perceptions About Triplet Chemotherapy Plus Bevacizumab for Metastatic Colorectal Cancer

Cost-effectiveness of apixaban compared to other anticoagulants in patients with atrial fibrillation in the real-world and trial settings

Deep learning–assisted prostate cancer detection on bi-parametric MRI: minimum training data size requirements and effect of prior knowledge

Neonatal neuroimaging findings in inborn errors of metabolism

Domains and determinants of retirement timing: A systematic review of longitudinal studies

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