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In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies

Cellular and molecular life sciences : CMLS, 2014-10, Vol.71 (20), p.4007-4026

2014

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Cellular senescence in malignant cells promotes tumor progression in mouse and patient Glioblastoma

Nature communications, 2023-01, Vol.14 (1), p.441-441, Article 441

2023

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Id4 promotes the elimination of the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal stem cells

eLife, 2019-09, Vol.8

2019

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Acquisition of Granule Neuron Precursor Identity Is a Critical Determinant of Progenitor Cell Competence to Form Shh-Induced Medulloblastoma

Cancer cell, 2008-08, Vol.14 (2), p.123-134

2008

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A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas

Nature communications, 2018-06, Vol.9 (1), p.2371-9, Article 2371

2018

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Olig2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma

Neuron (Cambridge, Mass.), 2007-02, Vol.53 (4), p.503-517

2007

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ID4 Is Required for Normal Ependymal Cell Development

Frontiers in neuroscience, 2021-04, Vol.15, p.668243-668243

2021

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The Central Nervous System-Restricted Transcription Factor Olig2 Opposes p53 Responses to Genotoxic Damage in Neural Progenitors and Malignant Glioma

Cancer cell, 2011-03, Vol.19 (3), p.359-371

2011

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RNA Profiling of the Human and Mouse Spinal Cord Stem Cell Niches Reveals an Embryonic-like Regionalization with MSX1+ Roof-Plate-Derived Cells

Stem cell reports, 2019-05, Vol.12 (5), p.1159-1177

2019

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PAK3 is a key signature gene of the glioma proneural subtype and affects its proliferation, differentiation and growth

Cellular oncology (Dordrecht), 2021-12, Vol.44 (6), p.1257-1271

2021

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GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity

Oncotarget, 2016-11, Vol.7 (48), p.79101-79116

2016

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Disruption of CK2β in Embryonic Neural Stem Cells Compromises Proliferation and Oligodendrogenesis in the Mouse Telencephalon

Molecular and Cellular Biology, 2010-06, Vol.30 (11), p.2737-2749

2010

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Cell of Origin of Brain and Spinal Cord Tumors

Advances in experimental medicine and biology, 2023, Vol.1394, p.85-101

2023

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Biosynthesis, Post-translation Modification, and Functional Characterization of Drm/Gremlin

The Journal of biological chemistry, 2000-03, Vol.275 (12), p.8785-8793

2000

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Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (22), p.8710-8715

2012

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Defects in chicken neuroretina misexpressing the BMP antagonist Drm/Gremlin

Developmental biology, 2005-07, Vol.283 (2), p.335-344

2005

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Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma

The Journal of clinical investigation, 2012-03, Vol.122 (3), p.911-922

2012

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TCF12 is mutated in anaplastic oligodendroglioma

Nature communications, 2015-06, Vol.6 (1), p.7207-7207, Article 7207

2015

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Novel regulation of PDGFRα activation in Glioblastoma

The FASEB journal, 2012-04, Vol.26 (S1)

2012

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GENE-54. A NOVEL MUTATION IN PRKCA IS THE MAJOR DRIVER OF CHORDOID GLIOMAS

Neuro-oncology (Charlottesville, Va.), 2017-11, Vol.19 (suppl_6), p.vi104-vi104

2017

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ANGI-04Olig2 REGULATES Wnt7b EXPRESSION AND VASCULATURE CHARACTERISTICS IN GLIOMA

Neuro-oncology (Charlottesville, Va.), 2015-11, Vol.17 (suppl 5), p.v41.4-v41

2015

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Heparan sulfate sulfatase SULF2 regulates PDGFR[alpha] signaling and growth in human and mouse malignant glioma

The Journal of clinical investigation, 2012-03, Vol.122 (3), p.911

2012

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Cooperative interactions of BRAF^sup V600E^ kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (22), p.8710

2012

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In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies

Cellular senescence in malignant cells promotes tumor progression in mouse and patient Glioblastoma

Id4 promotes the elimination of the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal stem cells

Acquisition of Granule Neuron Precursor Identity Is a Critical Determinant of Progenitor Cell Competence to Form Shh-Induced Medulloblastoma

A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas

Olig2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma

ID4 Is Required for Normal Ependymal Cell Development

The Central Nervous System-Restricted Transcription Factor Olig2 Opposes p53 Responses to Genotoxic Damage in Neural Progenitors and Malignant Glioma

RNA Profiling of the Human and Mouse Spinal Cord Stem Cell Niches Reveals an Embryonic-like Regionalization with MSX1+ Roof-Plate-Derived Cells

PAK3 is a key signature gene of the glioma proneural subtype and affects its proliferation, differentiation and growth

GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity

Disruption of CK2β in Embryonic Neural Stem Cells Compromises Proliferation and Oligodendrogenesis in the Mouse Telencephalon

Cell of Origin of Brain and Spinal Cord Tumors

Biosynthesis, Post-translation Modification, and Functional Characterization of Drm/Gremlin

Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy

Defects in chicken neuroretina misexpressing the BMP antagonist Drm/Gremlin

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

Isocitrate dehydrogenase wt and IDHmut adult-type diffuse gliomas display distinct alterations in ribosome biogenesis and 2’O-methylation of ribosomal RNA

Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma

TCF12 is mutated in anaplastic oligodendroglioma

Novel regulation of PDGFRα activation in Glioblastoma

GENE-54. A NOVEL MUTATION IN PRKCA IS THE MAJOR DRIVER OF CHORDOID GLIOMAS

ANGI-04Olig2 REGULATES Wnt7b EXPRESSION AND VASCULATURE CHARACTERISTICS IN GLIOMA

Heparan sulfate sulfatase SULF2 regulates PDGFR[alpha] signaling and growth in human and mouse malignant glioma

Cooperative interactions of BRAF^sup V600E^ kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy

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