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Review of Synthetic Routes and Final Forms of Integrase Inhibitors Dolutegravir, Cabotegravir, and Bictegravir

Organic process research & development, 2019-05, Vol.23 (5), p.716-729

Hughes, David L

2019

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Review of Synthetic Routes and Crystalline Forms of the Antiandrogen Oncology Drugs Enzalutamide, Apalutamide, and Darolutamide

Organic process research & development, 2020-03, Vol.24 (3), p.347-362

Hughes, David L

2020

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Patent Review of Manufacturing Routes to Oncology Drugs: Carfilzomib, Osimertinib, and Venetoclax

Organic process research & development, 2016-12, Vol.20 (12), p.2028-2042

Hughes, David L

2016

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Applications of Flow Chemistry in Drug Development: Highlights of Recent Patent Literature

Organic process research & development, 2018-01, Vol.22 (1), p.13-20

Hughes, David L

2018

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Patent Review of Manufacturing Routes to Recently Approved Oncology Drugs: Ibrutinib, Cobimetinib, and Alectinib

Organic process research & development, 2016-11, Vol.20 (11), p.1855-1869

Hughes, David L

2016

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Applications of Flow Chemistry in the Pharmaceutical Industry—Highlights of the Recent Patent Literature

Organic process research & development, 2020-10, Vol.24 (10), p.1850-1860

Hughes, David L.

2020

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A Thermally Stable Gold(III) Hydride: Synthesis, Reactivity, and Reductive Condensation as a Route to Gold(II) Complexes

Angewandte Chemie (International ed.), 2012-10, Vol.51 (42), p.10643-10646

International ed. in English, 2012

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Tweaking the bridge in metallocene Zr()/W() bimetallic hydrides

Dalton transactions : an international journal of inorganic chemistry, 2023-01, Vol.52 (2), p.394-48

2023

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Biocatalysis in Drug DevelopmentHighlights of the Recent Patent Literature

Organic process research & development, 2018-09, Vol.22 (9), p.1063-1080

Hughes, David L

2018

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Discovery and development of first in class antifungal caspofungin (CANCIDAS®)-A case study

Natural product reports, 2014-01, Vol.31 (1), p.15-34

2014

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Asymmetric Organocatalysis in Drug DevelopmentHighlights of Recent Patent Literature

Organic process research & development, 2018-05, Vol.22 (5), p.574-584

Hughes, David L

2018

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Quest for a Cure: Potential Small-Molecule Treatments for COVID-19, Part 2

Organic process research & development, 2021-05, Vol.25 (5), p.1089-1111

Hughes, David L

2021

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The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations

Journal of biomolecular structure & dynamics, 2023-12, Vol.ahead-of-print (ahead-of-print), p.1-15

2023

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Straightforward and Controlled Synthesis of Porphyrin–Phthalocyanine–Porphyrin Heteroleptic Triple‐Decker Assemblies

Chemistry : a European journal, 2020-08, Vol.26 (47), p.10724-10728

2020

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Patent Review of Manufacturing Routes to Recently Approved PARP Inhibitors: Olaparib, Rucaparib, and Niraparib

Organic process research & development, 2017-09, Vol.21 (9), p.1227-1244

Hughes, David L

2017

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Discotic Triphenylene Twins Linked through Thiophene Bridges: Controlling Nematic Behavior in an Intriguing Class of Functional Organic Materials

Journal of organic chemistry, 2012-05, Vol.77 (9), p.4288-4297

2012

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Review of the Patent Literature: Synthesis and Final Forms of Antiviral Drugs Tecovirimat and Baloxavir Marboxil

Organic process research & development, 2019-07, Vol.23 (7), p.1298-1307

Hughes, David L

2019

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Quest for a COVID-19 Cure by Repurposing Small-Molecule Drugs: Mechanism of Action, Clinical Development, Synthesis at Scale, and Outlook for Supply

Organic process research & development, 2020-06, Vol.24 (6), p.940-976

2020

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Patent Review of Synthetic Routes and Crystalline Forms of the CFTR-Modulator Drugs Ivacaftor, Lumacaftor, Tezacaftor, and Elexacaftor

Organic process research & development, 2019-11, Vol.23 (11), p.2302-2322

Hughes, David L

2019

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An Oxalate-Bridged Copper(II) Complex Combining Monodentate Benzoate, 2,2'-bipyridine and Aqua Ligands: Synthesis, Crystal Structure and Investigation of Magnetic Properties

Molecules (Basel, Switzerland), 2020-04, Vol.25 (8), p.1898

2020

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An Electrochemical Study of Frustrated Lewis Pairs: A Metal-Free Route to Hydrogen Oxidation

Journal of the American Chemical Society, 2014-04, Vol.136 (16), p.6031-6036

2014

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Are Heterogeneous Catalysts Precursors to Homogeneous Catalysts?

Journal of the American Chemical Society, 2001-10, Vol.123 (41), p.10139-10140

2001

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Review of Synthetic Routes and Crystalline Forms of the Oncology Drugs Capmatinib, Selpercatinib, and Pralsetinib

Organic process research & development, 2021-10, Vol.25 (10), p.2192-2204

Hughes, David L

2021

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Synthesis of a Class of Core-Modified Aza-BODIPY Derivatives

Journal of organic chemistry, 2014-09, Vol.79 (18), p.8932-8936

2014

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A Rare Example of Four-Coordinate Nonoxido Vanadium(IV) Alkoxide in the Solid State: Structure, Spectroscopy, and Magnetization Dynamics

Inorganic chemistry, 2018-09, Vol.57 (18), p.11393-11403

2018

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Review of Synthetic Routes and Final Forms of Integrase Inhibitors Dolutegravir, Cabotegravir, and Bictegravir

Review of Synthetic Routes and Crystalline Forms of the Antiandrogen Oncology Drugs Enzalutamide, Apalutamide, and Darolutamide

Patent Review of Manufacturing Routes to Oncology Drugs: Carfilzomib, Osimertinib, and Venetoclax

Applications of Flow Chemistry in Drug Development: Highlights of Recent Patent Literature

Patent Review of Manufacturing Routes to Recently Approved Oncology Drugs: Ibrutinib, Cobimetinib, and Alectinib

Applications of Flow Chemistry in the Pharmaceutical Industry—Highlights of the Recent Patent Literature

A Thermally Stable Gold(III) Hydride: Synthesis, Reactivity, and Reductive Condensation as a Route to Gold(II) Complexes

Tweaking the bridge in metallocene Zr()/W() bimetallic hydrides

Biocatalysis in Drug DevelopmentHighlights of the Recent Patent Literature

Discovery and development of first in class antifungal caspofungin (CANCIDAS®)-A case study

Asymmetric Organocatalysis in Drug DevelopmentHighlights of Recent Patent Literature

Quest for a Cure: Potential Small-Molecule Treatments for COVID-19, Part 2

The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations

Straightforward and Controlled Synthesis of Porphyrin–Phthalocyanine–Porphyrin Heteroleptic Triple‐Decker Assemblies

Patent Review of Manufacturing Routes to Recently Approved PARP Inhibitors: Olaparib, Rucaparib, and Niraparib

Discotic Triphenylene Twins Linked through Thiophene Bridges: Controlling Nematic Behavior in an Intriguing Class of Functional Organic Materials

Review of the Patent Literature: Synthesis and Final Forms of Antiviral Drugs Tecovirimat and Baloxavir Marboxil

Quest for a COVID-19 Cure by Repurposing Small-Molecule Drugs: Mechanism of Action, Clinical Development, Synthesis at Scale, and Outlook for Supply

Patent Review of Synthetic Routes and Crystalline Forms of the CFTR-Modulator Drugs Ivacaftor, Lumacaftor, Tezacaftor, and Elexacaftor

An Oxalate-Bridged Copper(II) Complex Combining Monodentate Benzoate, 2,2'-bipyridine and Aqua Ligands: Synthesis, Crystal Structure and Investigation of Magnetic Properties

An Electrochemical Study of Frustrated Lewis Pairs: A Metal-Free Route to Hydrogen Oxidation

Are Heterogeneous Catalysts Precursors to Homogeneous Catalysts?

Review of Synthetic Routes and Crystalline Forms of the Oncology Drugs Capmatinib, Selpercatinib, and Pralsetinib

Synthesis of a Class of Core-Modified Aza-BODIPY Derivatives

A Rare Example of Four-Coordinate Nonoxido Vanadium(IV) Alkoxide in the Solid State: Structure, Spectroscopy, and Magnetization Dynamics

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