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Applications of tumor chip technology

Lab on a chip, 2018-09, Vol.18 (19), p.2893-2912

2018

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Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels

Lab on a chip, 2016-01, Vol.16 (2), p.282-290

2016

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A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications

Lab on a chip, 2017-01, Vol.17 (3), p.511-520

2017

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Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis

Nature communications, 2020-10, Vol.11 (1), p.5400-5400, Article 5400

2020

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Organotypic stromal cells impact endothelial cell transcriptome in 3D microvessel networks

Scientific reports, 2022-11, Vol.12 (1), p.20434-16, Article 20434

2022

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A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays

Lab on a chip, 2013-08, Vol.13 (15), p.2990-2998

2013

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Targeting tumor-stromal interactions in triple-negative breast cancer using a human vascularized micro-tumor model

Breast cancer research : BCR, 2024-01, Vol.26 (1), p.5-5, Article 5

2024

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Endothelial-stromal interactions in angiogenesis

Current opinion in hematology, 2008-05, Vol.15 (3), p.204-209

Hughes, Christopher C W

2008

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TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype

Blood, 2008-05, Vol.111 (10), p.4997-5007

2008

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Exosomes as a Source of Biomarkers for Gastrointestinal Cancers

Cancers, 2023-02, Vol.15 (4), p.1263

2023

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mTORC2 mediates CXCL12-induced angiogenesis

Angiogenesis (London), 2016-07, Vol.19 (3), p.359-371

2016

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3D microtumors in vitro supported by perfused vascular networks

Scientific reports, 2016-08, Vol.6 (1), p.31589-31589, Article 31589

2016

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Of Mice and Not Men: Differences between Mouse and Human Immunology

The Journal of immunology (1950), 2004-03, Vol.172 (5), p.2731-2738

2004

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Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis

The FASEB journal, 2005-06, Vol.19 (8), p.1027-1029

2005

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Crosstalk Between Vascular Endothelial Growth Factor, Notch, and Transforming Growth Factor-β in Vascular Morphogenesis

Circulation research, 2008-03, Vol.102 (6), p.637-652

2008

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The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation

Molecular biology of the cell, 2011-10, Vol.22 (20), p.3791-3800

2011

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A modular microfluidic system based on a multilayered configuration to generate large-scale perfusable microvascular networks

Microsystems & nanoengineering, 2021, Vol.7 (1), p.4-4, Article 4

2021

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The vascular niche in next generation microphysiological systems

Lab on a chip, 2021-09, Vol.21 (17), p.3244-3262

2021

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In vitro perfused human capillary networks

Tissue engineering. Part C, Methods, 2013-09, Vol.19 (9), p.730-737

2013

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BMP9 induces EphrinB2 expression in endothelial cells through an Alk1-BMPRII/ActRII-ID1/ID3-dependent pathway: implications for hereditary hemorrhagic telangiectasia type II

Angiogenesis (London), 2012-09, Vol.15 (3), p.497-509

2012

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Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth

Biomaterials, 2017-02, Vol.116, p.118-129

2017

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Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering

Acta biomaterialia, 2016-10, Vol.43, p.122-138

2016

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Three-Dimensional Adult Cardiac Extracellular Matrix Promotes Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Tissue engineering. Part A, 2016-08, Vol.22 (15-16), p.1016-1025

2016

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Wnt Signaling Induces Matrix Metalloproteinase Expression and Regulates T Cell Transmigration

Immunity (Cambridge, Mass.), 2007-02, Vol.26 (2), p.227-239

2007

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GNAQ mutations drive port wine birthmark-associated Sturge-Weber syndrome: A review of pathobiology, therapies, and current models

Frontiers in human neuroscience, 2022-11, Vol.16, p.1006027-1006027

2022

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Applications of tumor chip technology

Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels

A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications

Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis

Organotypic stromal cells impact endothelial cell transcriptome in 3D microvessel networks

A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays

Targeting tumor-stromal interactions in triple-negative breast cancer using a human vascularized micro-tumor model

Endothelial-stromal interactions in angiogenesis

TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype

Exosomes as a Source of Biomarkers for Gastrointestinal Cancers

mTORC2 mediates CXCL12-induced angiogenesis

3D microtumors in vitro supported by perfused vascular networks

Of Mice and Not Men: Differences between Mouse and Human Immunology

Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis

Crosstalk Between Vascular Endothelial Growth Factor, Notch, and Transforming Growth Factor-β in Vascular Morphogenesis

The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation

A modular microfluidic system based on a multilayered configuration to generate large-scale perfusable microvascular networks

The vascular niche in next generation microphysiological systems

In vitro perfused human capillary networks

BMP9 induces EphrinB2 expression in endothelial cells through an Alk1-BMPRII/ActRII-ID1/ID3-dependent pathway: implications for hereditary hemorrhagic telangiectasia type II

Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth

Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering

Three-Dimensional Adult Cardiac Extracellular Matrix Promotes Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Wnt Signaling Induces Matrix Metalloproteinase Expression and Regulates T Cell Transmigration

GNAQ mutations drive port wine birthmark-associated Sturge-Weber syndrome: A review of pathobiology, therapies, and current models

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