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Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial

The Lancet (British edition), 2015-05, Vol.385 (9982), p.2077-2087

2015

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A phase I ascending single-dose study of the safety, tolerability, and pharmacokinetics of bosutinib (SKI-606) in healthy adult subjects

Cancer chemotherapy and pharmacology, 2012-01, Vol.69 (1), p.221-227

2012

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Effect of Ketoconazole on the Pharmacokinetics of Oral Bosutinib in Healthy Subjects

Journal of clinical pharmacology, 2011-12, Vol.51 (12), p.1721-1727

2011

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Severe gastrointestinal toxicity with administration of trametinib in combination with dabrafenib and ipilimumab

Pigment cell and melanoma research, 2015-09, Vol.28 (5), p.611-612

2015

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Long-Range Disruption of Gene Expression by a Selectable Marker Cassette

Proceedings of the National Academy of Sciences - PNAS, 1996-11, Vol.93 (23), p.13090-13095

1996

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Safety, Pharmacokinetics, and Pharmacodynamics of the TLR4 Agonist GSK1795091 in Healthy Individuals: Results from a Randomized, Double-blind, Placebo-controlled, Ascending Dose Study

Clinical therapeutics, 2020-08, Vol.42 (8), p.1519-1534.e33

2020

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Pharmacokinetics of oral neratinib during co‐administration of ketoconazole in healthy subjects

British journal of clinical pharmacology, 2011-04, Vol.71 (4), p.522-527

2011

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A randomized, crossover, placebo- and moxifloxacin-controlled study to evaluate the effects of bosutinib (SKI-606), a dual Src/Abl tyrosine kinase inhibitor, on cardiac repolarization in healthy adult subjects

International journal of cancer, 2012-08, Vol.131 (3), p.E304-E311

2012

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Fusion-Protein Truncation Provides New Insights into Leukemogenesis

Proceedings of the National Academy of Sciences - PNAS, 2004-12, Vol.101 (49), p.16985-16986

2004

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A double-blind, randomized, multiple-dose, parallel-group study to characterize the occurrence of diarrhea following two different dosing regimens of neratinib, an irreversible pan-ErbB receptor tyrosine kinase inhibitor

Cancer chemotherapy and pharmacology, 2012-07, Vol.70 (1), p.191-199

2012

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ETO interacting proteins

Oncogene, 2004-05, Vol.23 (24), p.4270-4274

2004

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HDAC4: A corepressor controlling bone development

Cell, 2004-11, Vol.119 (4), p.448-449

Hug, Bruce A.

2004

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Oligomerization of ETO Is Obligatory for Corepressor Interaction

Molecular and Cellular Biology, 2001-01, Vol.21 (1), p.156-163

2001

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Characterization of tumor antigen expression and myeloid immune profiles to inform the development of immune stimulating antibody conjugates (ISACs)

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.2557-2557

2022

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Cooperative function of Aml1-ETO corepressor recruitment domains in the expansion of primary bone marrow cells

Cancer research (Chicago, Ill.), 2002-05, Vol.62 (10), p.2906-2912

2002

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A phase Ib single-arm study of bintrafusp alfa for the treatment of pretreated, locally advanced/unresectable or metastatic urothelial cancer

Journal of clinical oncology, 2021-02, Vol.39 (6_suppl), p.TPS501-TPS501

2021

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Endothelial cells in physiology and in the pathophysiology of vascular disorders

Blood, 1998-05, Vol.91 (10), p.3527-3561

1998

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Randomized Phase IIIb Study Of Rapid Vitamin K Antagonist Reversal In Patients Requiring An Urgent Surgical Procedure: Four-Factor Prothrombin Complex Concentrate Is Superior To Plasma

Blood, 2013-11, Vol.122 (21), p.3588-3588

2013

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HDAC4

Cell, 2004-11, Vol.119 (4), p.448-449

Hug, Bruce A.

2004

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Abstract 4707: Genetically engineered NY-ESO-1-specific T cells in HLA-A2+ patients with synovial sarcoma

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4707-4707

2015

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Phase 1 study of the BRAF inhibitor dabrafenib (D) with or without the MEK inhibitor trametinib (T) in combination with ipilimumab (Ipi) for V600E/K mutation–positive unresectable or metastatic melanoma (MM)

Journal of clinical oncology, 2014-05, Vol.32 (15_suppl), p.2511-2511

2014

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A Chromatin Immunoprecipitation Screen Reveals Protein Kinase Cβ as a Direct RUNX1 Target Gene

The Journal of biological chemistry, 2004-01, Vol.279 (2), p.825-830

2004

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ETO interacting proteins: The RUNX gene family

Oncogene, 2004, Vol.23 (24), p.4270-4274

2004

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Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3

Molecular and Cellular Biology, 1996-06, Vol.16 (6), p.2906-2912

1996

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A chromatin immunoprecipitation screen reveals protein kinase Cbeta as a direct RUNX1 target gene

The Journal of biological chemistry, 2004-01, Vol.279 (2), p.825-830

2004

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Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial

A phase I ascending single-dose study of the safety, tolerability, and pharmacokinetics of bosutinib (SKI-606) in healthy adult subjects

Effect of Ketoconazole on the Pharmacokinetics of Oral Bosutinib in Healthy Subjects

Severe gastrointestinal toxicity with administration of trametinib in combination with dabrafenib and ipilimumab

Long-Range Disruption of Gene Expression by a Selectable Marker Cassette

Safety, Pharmacokinetics, and Pharmacodynamics of the TLR4 Agonist GSK1795091 in Healthy Individuals: Results from a Randomized, Double-blind, Placebo-controlled, Ascending Dose Study

Pharmacokinetics of oral neratinib during co‐administration of ketoconazole in healthy subjects

A randomized, crossover, placebo- and moxifloxacin-controlled study to evaluate the effects of bosutinib (SKI-606), a dual Src/Abl tyrosine kinase inhibitor, on cardiac repolarization in healthy adult subjects

Fusion-Protein Truncation Provides New Insights into Leukemogenesis

A double-blind, randomized, multiple-dose, parallel-group study to characterize the occurrence of diarrhea following two different dosing regimens of neratinib, an irreversible pan-ErbB receptor tyrosine kinase inhibitor

ETO interacting proteins

HDAC4: A corepressor controlling bone development

Oligomerization of ETO Is Obligatory for Corepressor Interaction

Characterization of tumor antigen expression and myeloid immune profiles to inform the development of immune stimulating antibody conjugates (ISACs)

Cooperative function of Aml1-ETO corepressor recruitment domains in the expansion of primary bone marrow cells

A phase Ib single-arm study of bintrafusp alfa for the treatment of pretreated, locally advanced/unresectable or metastatic urothelial cancer

Endothelial cells in physiology and in the pathophysiology of vascular disorders

Randomized Phase IIIb Study Of Rapid Vitamin K Antagonist Reversal In Patients Requiring An Urgent Surgical Procedure: Four-Factor Prothrombin Complex Concentrate Is Superior To Plasma

HDAC4

Abstract 4707: Genetically engineered NY-ESO-1-specific T cells in HLA-A2+ patients with synovial sarcoma

Phase 1 study of the BRAF inhibitor dabrafenib (D) with or without the MEK inhibitor trametinib (T) in combination with ipilimumab (Ipi) for V600E/K mutation–positive unresectable or metastatic melanoma (MM)

A Chromatin Immunoprecipitation Screen Reveals Protein Kinase Cβ as a Direct RUNX1 Target Gene

ETO interacting proteins: The RUNX gene family

Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3

A chromatin immunoprecipitation screen reveals protein kinase Cbeta as a direct RUNX1 target gene

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