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Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis

Annual review of nutrition, 2016-07, Vol.36 (1), p.275-299

2016

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Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr−/− mice

Journal of lipid research, 2018-09, Vol.59 (9), p.1714-1728

2018

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Polygenic Versus Monogenic Causes of Hypercholesterolemia Ascertained Clinically

Arteriosclerosis, thrombosis, and vascular biology, 2016-12, Vol.36 (12), p.2439

2016

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Antiatherogenic properties of flavonoids: Implications for cardiovascular health

Canadian journal of cardiology, 2010-03, Vol.26, p.17A-21A

2010

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Nobiletin Prevents High-Fat Diet-Induced Dysregulation of Intestinal Lipid Metabolism and Attenuates Postprandial Lipemia

Arteriosclerosis, thrombosis, and vascular biology, 2022-02, Vol.42 (2), p.127

2022

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Naringenin Prevents Dyslipidemia, Apolipoprotein B Overproduction, and Hyperinsulinemia in LDL Receptor–Null Mice With Diet-Induced Insulin Resistance

Diabetes (New York, N.Y.), 2009-10, Vol.58 (10), p.2198-2210

2009

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The citrus flavonoid nobiletin confers protection from metabolic dysregulation in high-fat-fed mice independent of AMPK[S]

Journal of lipid research, 2020-03, Vol.61 (3), p.387-402

2020

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Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr−/− mice[S]

Journal of lipid research, 2013-03, Vol.54 (3), p.711-724

2013

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Naringenin Prevents Obesity, Hepatic Steatosis, and Glucose Intolerance in Male Mice Independent of Fibroblast Growth Factor 21

Endocrinology (Philadelphia), 2015-06, Vol.156 (6), p.2087-2102

2015

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Fibroblast Growth Factor 21 Reduces the Severity of Cerulein-Induced Pancreatitis in Mice

Gastroenterology (New York, N.Y. 1943), 2009-11, Vol.137 (5), p.1795-1804

2009

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Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice

Arteriosclerosis, thrombosis, and vascular biology, 2010-04, Vol.30 (4), p.742

2010

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PPARδ activation attenuates hepatic steatosis in Ldlr−/− mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity

Journal of lipid research, 2014-07, Vol.55 (7), p.1254-1266

2014

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ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia

Current opinion in lipidology, 2017-04, Vol.28 (2), p.193-200

2017

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Citrus flavonoids and lipid metabolism

Current opinion in lipidology, 2013-02, Vol.24 (1), p.34-40

2013

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Bempedoic acid: effects on lipoprotein metabolism and atherosclerosis

Current opinion in lipidology, 2019-02, Vol.30 (1), p.1

2019

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molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin

Journal of lipid research, 2007-03, Vol.48 (3), p.699-708

2007

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NPC1L1: evolution from pharmacological target to physiological sterol transporter

Arteriosclerosis, thrombosis, and vascular biology, 2006-11, Vol.26 (11), p.2433

2006

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Selective Up-regulation of LXR-regulated Genes ABCA1, ABCG1, and APOE in Macrophages through Increased Endogenous Synthesis of 24(S),25-Epoxycholesterol

The Journal of biological chemistry, 2007-02, Vol.282 (8), p.5207-5216

2007

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Inhibition of Microsomal Triglyceride Transfer Protein Expression and Apolipoprotein B100 Secretion by the Citrus Flavonoid Naringenin and by Insulin Involves Activation of the Mitogen-Activated Protein Kinase Pathway in Hepatocytes

Diabetes (New York, N.Y.), 2005-06, Vol.54 (6), p.1676-1683

2005

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Peroxisome proliferator-activated receptor δ: a multifaceted metabolic player

Current opinion in lipidology, 2013-04, Vol.24 (2), p.171-177

2013

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Lipid Incorporation Inhibits Src-Dependent Assembly of Fibronectin and Type I Collagen by Vascular Smooth Muscle Cells

Circulation research, 2009-04, Vol.104 (7), p.832-841

2009

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Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation

PPAR Research, 2012-01, Vol.2012, p.857142-9

2012

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Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP

Journal of lipid research, 2001-05, Vol.42 (5), p.725-734

2001

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PCSK9: Regulation and Target for Drug Development for Dyslipidemia

Annual review of pharmacology and toxicology, 2017-01, Vol.57, p.223

2017

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Apolipoprotein C-III: Going Back to the Future for a Lipid Drug Target

Circulation research, 2013-05, Vol.112 (11), p.1405-1408

2013

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Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis

Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr−/− mice

Polygenic Versus Monogenic Causes of Hypercholesterolemia Ascertained Clinically

Antiatherogenic properties of flavonoids: Implications for cardiovascular health

Nobiletin Prevents High-Fat Diet-Induced Dysregulation of Intestinal Lipid Metabolism and Attenuates Postprandial Lipemia

Naringenin Prevents Dyslipidemia, Apolipoprotein B Overproduction, and Hyperinsulinemia in LDL Receptor–Null Mice With Diet-Induced Insulin Resistance

The citrus flavonoid nobiletin confers protection from metabolic dysregulation in high-fat-fed mice independent of AMPK[S]

Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr−/− mice[S]

Naringenin Prevents Obesity, Hepatic Steatosis, and Glucose Intolerance in Male Mice Independent of Fibroblast Growth Factor 21

Fibroblast Growth Factor 21 Reduces the Severity of Cerulein-Induced Pancreatitis in Mice

Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice

PPARδ activation attenuates hepatic steatosis in Ldlr−/− mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity

ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia

Citrus flavonoids and lipid metabolism

Bempedoic acid: effects on lipoprotein metabolism and atherosclerosis

molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin

NPC1L1: evolution from pharmacological target to physiological sterol transporter

Selective Up-regulation of LXR-regulated Genes ABCA1, ABCG1, and APOE in Macrophages through Increased Endogenous Synthesis of 24(S),25-Epoxycholesterol

Inhibition of Microsomal Triglyceride Transfer Protein Expression and Apolipoprotein B100 Secretion by the Citrus Flavonoid Naringenin and by Insulin Involves Activation of the Mitogen-Activated Protein Kinase Pathway in Hepatocytes

Peroxisome proliferator-activated receptor δ: a multifaceted metabolic player

Lipid Incorporation Inhibits Src-Dependent Assembly of Fibronectin and Type I Collagen by Vascular Smooth Muscle Cells

Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation

Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP

PCSK9: Regulation and Target for Drug Development for Dyslipidemia

Apolipoprotein C-III: Going Back to the Future for a Lipid Drug Target

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